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Results for: Pharmacology

SCCM Pod-526 CCM: Alteplase Dosing in Pulmonary Embolism

Host Samantha Gambles Farr, MSN, AG-ACNP, FNP-C, RNFA, is joined by Roman Melamed, MD, to discuss the comparative effectiveness of reduced-dose versus...

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SCCM Pod-522 PCCM: Early Adrenaline Infusion Versus Standard Fluid Resuscitation in Children With Septic Shock

Host Elizabeth H. Mack, MD, MS, FCCM, is joined by Luregn J. Schlapbach, MD, PhD, FCICM, to discuss the Pediatric Critical Care Medicine arti...


Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage

A Statement for Healthcare Professionals from the Neurocritical Care Society and Society of Critical Care Medicine​.


Guidelines for Sustained Neuromuscular Blockade in the Adult Critically Ill Patient

An SSCM/ASHP Joint Guideline, this is an update to the 2002 version of "Clinical practice guidelines for sustained neuromuscular blockade in...


Timing of Antibiotics in Septic Patients With Septic Arthritis

When should antibiotics be administered in septic patients with septic arthritis? This Concise Critical Appraisal reviews a recent study that sought t...

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Push-Dose Vasopressor Safety and Efficacy

Are push-dose vasopressors (PDPs) safe and effective for patients with hypotension outside the operating room? This Concise Critical Appraisal covers ...

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Concise Critical Appraisal: Hydrocortisone and Fludrocortisone Versus Hydrocortisone Only

Is hydrocortisone for septic shock best used alone or in combination with fludrocortisone? This Concise Critical Appraisal explores a retrospective co...

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Concise Critical Appraisal: Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest

Although several trials have examined in-hospital cardiac arrest (IHCA), only two trials in the past decade have examined the use of vasopressin and g...

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Tocilizumab May Reduce Mortality in Certain COVID-19 Patients

Two recent trials suggest that immune-damping drugs such as tocilizumab may reduce mortality in patients with severe COVID-19.

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Concise Critical Appraisal: Early Use of Tranexamic Acid in the Treatment of Gastrointestinal Bleeds

This Concise Critical Appraisal offers a deep dive into the HALT-IT trial, which investigated whether early use of tranexamic acid to treat acute seve...

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Sharing Data is the Key to Unlocking Remdesivir Challenges

Critical care teams should consider using remdesivir to treat patients with severe acute SARS-CoV-2 infection, but supply of the drug is limited and b...

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Concise Critical Appraisal: Early Sedation Using Dexmedetomidine in Critically Ill Patients

Shehabi et al (N Engl J Med. 2019;380:2506-2517) set out to examine the effects of using dexmedetomidine as the primary agent for early sedation among...

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Concise Critical Appraisal: Antipsychotic Medications for Delirium in the ICU

Girard et al (N Engl J Med. 2018;379:2506-2516) and Page et al (Lancet Respir Med. 2013;1:515-523) evaluated the treatment of acute delirium with anti...

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SCCM Pod-503: Current Concepts: Toxidromes and Illicit Drug Abuse In the ICU

This is the third episode of SCCM’s Current Concepts Series, in which authors unveil exclusive insights into the 2024 Current Concepts Course. D...

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SCCM Pod-494: Mastering CRRT: Optimal Anticoagulation and Citrate Selection

Pamela M. Peeke MD, MPH, FACP, FACSM, is joined by Rajesh Speer, PharmD, MSHA, MS, to delve into continuous renal replacement therapy (CRRT) and antic...

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SCCM Pod-468: When Should Antibiotics Be Used to Treat Respiratory Infections?

Although only a small number of patients hospitalized with COVID-19 present with a secondary bacterial pneumonia, a large percentage are unnecessarily...


SCCM Pod-463 CCM: Clazakizumab for COVID-19: Friend or Foe?

Clazakizumab is a monoclonal antibody against human interleukin-6 that may benefit patients hospitalized with severe or critical COVID-19 accompanied ...

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SCCM Pod-31 CC: Prophylactic Antimicrobial Use in the ICU

Phil Barie, MD, MBA, FCCM, discusses his article from the April 2006 issue of Critical Connections on antibiotic prophylaxis.

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SCCM Pod-34 CCM: Lorazepam vs. Propofol

Shannon S. Carson, MD, as well as John P. Kress, MD, discuss their article from the May 2006 Critical Care Medicine, "A Randomized Trial of Inter...

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SCCM Pod-40 CCM: Initial Antimicrobial Treatment of MRSA

Marin Kollef, MD, discusses his article in the August issue of Critical Care Medicine, "Methicillin-Resistant Staphylococcus aureus Sterile-Site ...

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SCCM Pod-57 CCM: Heparin-Induced Thrombocytopenia

Stanley Nasraway, MD, FCCM, discusses an article in the December issue of Critical Care Medicine "Heparin-induced thrombocytopenia in the critica...


SCCM Pod-58 CC: Cardiology Pharmacotherapies

Frederick P. Ognibene, MD, FCCM, discusses his goals as the Society's president for 2007 as well as his decades-long involvement in SCCM and the c...


SCCM Pod-66 2007 Congress Special: Furosemide and Albumin in ARDS

Gregory Martin, MD, discusses some of the topics from his presentation during the 36th Critical Care Congress, "Furosemide and Albumin in ARDS.&q...


SCCM Pod-69 2007 Congress Special: Epinephrine Versus Norepinephrine for Septic Shock

Djillali Annane, MD, discusses a study on epinephrine versus norepinephrine for septic shock he presented during the 36th Critical Care Congress.

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SCCM Pod-93 ACCM Recommendations for Corticosteroid Insufficiency

Paul Marik, MD, FCCM, discusses the June Critical Care Medicine article, "Recommendations for the Diagnosis and Management of Corticosteroid Insu...

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SCCM Pod-131 CCM: Dexmedetomidine vs. Midazolam: A Cost Minimization Analysis

Joseph F. Dasta, MSc, FCCM, discusses his article published in the February 2010 issue of Critical Care Medicine, titled “A Cost Minimization An...


SCCM Pod-133 CCM: Human Factors to Medication and Patient Safety in the ICU

Matthew C. Scanlon, MD, discuses is article, “Value of Human Factors to Medication and Patient Safety in the Intensive Care Unit,” publish...


SCCM Pod-143 PCCM: The Effects of Heparin in Infants After Catheter-Related Thrombosis

Alan R. Schroeder, MD, discusses his article, “A Continuous Heparin Infusion Does Not Prevent Catheter-Related Thrombosis in Infants After Cardi...


SCCM Pod-148 Adjunctive Corticosteroid Therapy in Pediatric Sepsis

Jerry J. Zimmerman, MD, PhD, FCCM, discusses his article published in the January Pediatric Critical Care Medicine, titled “Adjunctive Corticost...


SCCM Pod-157 Sedation Strategies in the ICU

Troy E. Batterton, PharmD, and Dean Sandifer, MD, discuss sedation strategies in critical care, including designing, building and maintaining protocol...

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SCCM Pod-197 CCM: Sedative Doses, Mechanical Ventilation and Delirium

Michael Weinstein, MD, FACS, FCCP, speaks with Christopher W. Seymour, MD, MSc, lead author on an article published in the October Critical Care Medic...


SCCM Pod-205 CCM: New Pain, Agitation and Delirium Guidelines

Jeffrey Guy, MD, MSc, MMHC, speaks with Juliana Barr, MD, FCCM, lead author on the Society of Critical Care Medicine's American College of Critica...


SCCM Pod-237 Evaluation of a Pharmacist-Managed Methadone Taper in the PICU

Margaret Parker, MD, MCCM, speaks with Katherine J. Steineck, PharmD, pediatric clinical pharmacist at the University of Minnesota Amplatz Children&rs...

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SCCM Pod-259 NEJM Study Examines if Simvastatin Improves ARDS Outcomes

Todd Fraser, MD, speaks with Daniel F. McAuley, MD, about his article, “Simvastatin in the Acute Respiratory Distress Syndrome,” published...


SCCM Pod-281 A Survey on the Sequence of Medications for Treatment of Hyperkalemia in the PICU

Margaret Parker, MD, MCCM, speaks with Nnenna O. Chime, MD, MPH, about the article, “A Survey Demonstrating Lack of Consensus on the Sequence of...


SCCM Pod-308 Four-Factor Prothrombin Complex Concentrate Versus Plasma For Rapid Vitamin K Antagonis

Margaret Parker, MD, MCCM, speaks with Joshua N. Goldstein, MD, PhD, FACEP, FAHA, about the article, “Four-factor prothrombin complex concentrat...


SCCM Pod-309 Overall Hypothermia Update

Margaret Parker, MD, MCCM, speaks with Benjamin Abella, MD, about his upcoming talk, “Overall Hypothermia Update,“ which he will present a...


SCCM Pod-313 Idarucizumab for Dabigatran Reversal

Margaret Parker, MD, MCCM, speaks with SCCM President Todd Dorman, MD, FCCM. Dr. Dorman is Senior Associate Dean for Education Coordination, Associate...

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SCCM Pod-315 Pharmacological Therapies for Intracranial Hypertension in Children With Severe TBI

Margaret Parker, MD, MCCM, speaks with Steven L. Shein, MD, about the article, “Effectiveness of Pharmacological Therapies for Intracranial Hype...


SCCM Pod-316 The SPLIT Randomized Clinical Trial

Todd Fraser, MD, speaks with Paul Young, FCICM, about the article, “Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury A...


SCCM Pod-317 Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients

Todd Fraser, MD, speaks with Nick Daneman, MD, about the article, “Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill...

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SCCM Pod-318 A Multicenter Evaluation of Prolonged Empiric Antibiotic Therapy in Adult ICUs in the U

Michael S. Weinstein, MD, FACS, FCCM, speaks with Zachariah Thomas, PharmD, about the article, “A Multicenter Evaluation of Prolonged Empiric An...

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SCCM Pod-320 Impact of Sepsis Classification and Multidrug-Resistance Status on Outcome Among Patien

Margaret Parker, MD, MCCM, speaks with Marin H. Kollef, MD, about the article, “Impact of Sepsis Classification and Multidrug-Resistance Status ...


SCCM Pod-331 Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approa

Todd Fraser, MD, speaks with Scott Kaatz, DO, FACP, SFHM, about his talk given at the 45th Critical Care Congress on, “Bleeding Management and R...


SCCM Pod-332 Dexmedetomidine Use in Critically-Ill Children with Acute Respiratory Failure

Margaret Parker, MD, MCCM, speaks with Mary Jo C. Grant, APRN, PhD, about the article, “Dexmedetomidine Use in Critically-Ill Children with Acut...


SCCM Pod-334 Vasopressors: Future Research

Margaret Parker, MD, MCCM, speaks with Lakhmir S. Chawla, MD, about future research related to the Congress session “Bench-Pressing in the ICU: ...


SCCM Pod-337 Clinical Practice Guidelines for Sustained Neuromuscular Blockade in the Adult Critical

Todd Fraser, MD, speaks with Michael J. Murray, MD, PhD, FCCM, FCCP, about the article, “Clinical Practice Guidelines for Sustained Neuromuscula...


SCCM Pod-346 Delays in Antibiotic Administration for Sepsis

Todd Fraser, MD, speaks with Christopher W. Seymour, MD, MSc, about the article, “Delays From First Medical Contact to Antibiotic Administration...

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SCCM Pod-358 Liberal Glycemic Control in Critically Ill Patients With Type 2 Diabetes

Ludwig Lin, MD, speaks with Palash Kar, MBBS, about the article, “Liberal Glycemic Control in Critically Ill Patients With Type 2 Diabetes: An E...

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SCCM Pod-361 Antibiotic Therapy in Comatose Mechanically Ventilated Patients Following Aspiration

Dr. Fraser, MD, speaks with Jean Baptiste Lascarrou, MD, about the article, "Antibiotic Therapy in Comatose Mechanically Ventilated Patients Foll...

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SCCM Pod-367 Variability in Antibiotic Use Across PICUs

Margaret Parker, MD, MCCM, speaks with Thomas V. Brogan, MD, about the article “Variability in Antibiotic Use Across PICUs,” published in ...


SCCM Pod-368 Achieving Fluid Balance

Kyle Enfield, MD, speaks with Colin K. Grissom, MD, FCCM, and Matthew W. Semler, MD, about fluid management in the critically ill. Dr. Grissom present...

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SCCM Pod-374 Angiotensin II Treatment in Patients with Vasodilatory Shock and Renal Replacement Ther

Todd Fraser, MD, speaks with Rinaldo Bellomo, MD, MBBS, FRACP, FCICM, FAAHMS, about the article "Outcomes in Patients with Vasodilatory Shock and...

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SCCM Pod-376 2018 PADIS Guidelines

Kyle B. Enfield, MD, speaks with John W. Devlin, PharmD, FCCM, about the article "Clinical Practice Guidelines for the Prevention and Management ...


SCCM Pod-378 Procalcitonin Guidance during Antibiotics Management

Ranjit Deshpande, MD, and Simon W. Lam, PharmD, MS, BCPS, BCCCP, FCCM, discuss procalcitonin guidance during different phases of antibiotics managemen...

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SCCM Pod-383 Anticoagulant Reversal

Ranjit Deshpande, MD, and Mark D. Cipolle, MD, PhD, FCCM, discuss Dr. Cipolle's talk from the 48th Critical Care Congress on what's new in ant...


SCCM Pod-429 Drug Dosing Considerations in AKI and RRT

Continuous renal replacement therapy (CRRT) is complex, and dosing varies among institutions. Review dosing regimens, utilization in COVID-19 patients...

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SCCM Pod-439 The Association Between Antibiotic Delay and Hospital Mortality

Explore the correlation between antibiotic delay and hospital mortality in patients with sepsis in this podcast.


SCCM Pod-440 Optimal Sedation in Patients Who Receive Neuromuscular Blocking Agent Infusions for Tre

Two previously published trials presented equivocal evidence on the effect of neuromuscular blocking agent infusions in patients with acute respirator...

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REDISCOVER-ICU: Utilizing Data to Study Drug Repurposing Beyond COVID-19

The COVID-19 pandemic exposed significant gaps in the healthcare system, such as healthcare inequities and the need for more treatment options for int...

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World-Renowned Experts at the 2024 Critical Care Congress

SCCM is thrilled to bring world-renowned thought leaders to the 2024 Critical Care Congress to discuss innovative developments and hot topics in criti...


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