Michael S. Weinstein, MD, FACS, FCCM, speaks with Zachariah Thomas, PharmD, about the article, “A Multicenter Evaluation of Prolonged Empiric Antibiotic Therapy in Adult ICUs in the United States*,” published in Critical Care Medicine. Dr. Thomas works as Director of Global Health Science at The Medicines Company in Parsippany, New Jersey. In this article, Dr. Thomas and coauthors seek to determine the rate of prolonged empiric antibiotic therapy in adult ICUs in the United States.