Jeffrey Guy, MD, MSc, MMHC, speaks with Juliana Barr, MD, FCCM, lead author on the Society of Critical Care Medicine's American College of Critical Care Medicine, “Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit,” published in the January Critical Care Medicine. The guidelines provide a roadmap for developing integrated, evidence-based, and patient-centered protocols for preventing and treating pain, agitation and delirium (PAD) in critically ill patients. Bundles included in the guideline link management strategies with other intensive care unit (ICU) interventions, such as spontaneous awakening trials and early mobility protocols. Barr is an Associate ICU Medical Director at the Veterans Affairs Palo Alto Health Care System in Palo Alto, California, and Associate Professor in Anesthesia at Stanford University.