PANDEM Guidelines for Infants and Children
As many as three out of five children i...
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Concise Critical Appraisal: Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest
Although several trials have examined in-hospital cardiac arrest (IHCA), only two trials in the past decade have examined the use of vasopressin and g...
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Tocilizumab May Reduce Mortality in Certain COVID-19 Patients
Two recent trials suggest that immune-damping drugs such as tocilizumab may reduce mortality in patients with severe COVID-19.
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Concise Critical Appraisal: Early Use of Tranexamic Acid in the Treatment of Gastrointestinal Bleeds
This Concise Critical Appraisal offers a deep dive into the HALT-IT trial, which investigated whether early use of tranexamic acid to treat acute seve...
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Concise Critical Appraisal: Dexamethasone Use in the Treatment of ARDs
Villar et al (Lancet Respir Med. 2020;8:267-276) attempted to demonstrate the effect...
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Concise Critical Appraisal: Antipsychotic Medications for Delirium in the ICU
Girard et al (N Engl J Med. 2018;379:2506-2516) and Page et al (Lancet Respir Med. 2013;1:515-523) evaluated the treatment of acute delirium with anti...
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