SCCM COVID-19 Journal Articles

Shown below are all recently published articles from the Society of Critical Care Medicine’s journals, Critical Care Medicine, Pediatric Critical Care Medicine, and Critical Care Explorations, relating to the COVID-19 pandemic.

As articles are accepted and published, this list will be updated.

Find all of SCCM's COVID-19 Resources

The Latest COVID-19 Articles

Preintubation Sequential Organ Failure Assessment Score for Predicting COVID-19 Mortality: External Validation Using Electronic Health Record From 86 U.S. Healthcare Systems to Appraise Current Ventilator Triage Algorithms
Keller MB, Wang J, Nason M, et al. Critical Care Medicine

Lung-Dependent Areas Collapse, Monitored by Electrical Impedance Tomography, May Predict the Oxygenation Response to Prone Ventilation in COVID-19 Acute Respiratory Distress Syndrome
Cardinale M, Boussen S, Cungi PJ, et al. Critical Care Medicine

Early Clinical and Electrophysiological Brain Dysfunction Is Associated With ICU Outcomes in COVID-19 Critically Ill Patients With Acute Respiratory Distress Syndrome: A Prospective Bicentric Observational Study
Benghanem S, Cariou A, Diehl JL, et al. Critical Care Medicine

Predictive Algorithms for a Crisis
Sotillo CL, Franco I, Arriaga AF. Critical Care Medicine

Can Early Electroencephalography Findings Predict Survival and Functional Outcome in Patients With Severe COVID-19 Infection?
Bermeo-Ovalle A, Naidech AM. Critical Care Medicine

Validation of Respiratory Rate-Oxygenation Index in Patients With COVID-19–Related Respiratory Failure
Myers LC, Mark D, Ley B, et al. Critical Care Medicine

Acquired von Willebrand Syndrome and Desmopressin Resistance During Venovenous Extracorporeal Membrane Oxygenation in Patients With COVID-19: A Prospective Observational Study
Kalbhenn J, Glonnegger H, Büchsel M, et al. Critical Care Medicine

Neurologic Outcomes of Survivors of COVID-19–Associated Acute Respiratory Distress Syndrome Requiring Intubation
Jaquet P, Legouy C, Le Fevre L, et al. Critical Care Medicine

Association of Frailty, Organ Support, and Long-Term Survival in Critically Ill Patients With COVID-19
Taniguchi LU, Avelino-Silva TJ, Dias MB, et al. Critical Care Explorations

Sedation Practices in the PICU: An Unexpected Casualty of COVID-19
Pumphrey K, Bouzaher A, Achuff BJ, et al. Critical Care Explorations

Lung Ultrasound to Assist ICU Admission Decision-Making Process of COVID-19 Patients With Acute Respiratory Failure
Aguersif A, Sarton B, Bouharaoua S, et al. Critical Care Explorations

Comparison of Clinical Profiles and Mortality Outcomes Between Influenza and COVID-19 Patients Invasively Ventilated in the ICU: A Retrospective Study From All Paris Public Hospitals From 2016 to 2021
Marois C, Nedelec T, Pelle J, et al. Critical Care Explorations

Postintensive Care Syndrome-Family Associated With COVID-19 Infection
Shirasaki K, Hifumi T, Isokawa S, et al. Critical Care Explorations

Adoption and Deadoption of Medications to Treat Hospitalized Patients With COVID-19
Barbash IJ, Davis BS, Minturn JS, et al. Critical Care Explorations

Sleep and Circadian Health of Critical COVID-19 Survivors 3 Months After Hospital Discharge
Benítez ID, Moncusí-Moix A, Vaca R, et al. Critical Care Medicine

Patient-Centered Outcomes Following COVID-19: Frailty and Disability Transitions in Critical Care Survivors
Taniguchi LU, Avelino-Silva TJ, Dias MB, et al. Critical Care Medicine

CytoSorb Rescue for COVID-19 Patients With Vasoplegic Shock and Multiple Organ Failure: A Prospective, Open-Label, Randomized Controlled Pilot Study
Stockmkann H, Thelen P, Stroben F, et al. Critical Care Medicine

COVID-19, Critical Illness, and Sleep
Chatterjee AB. Critical Care Medicine

Frailty and Disability: Predictors or Outcomes or Both in Post COVID-19
O’Malley PA. Critical Care Medicine

Is This the Beginning of the End of Cytokine Adsorption?
Kielstein JT, Zarbock A. Critical Care Medicine

Intracranial Hemorrhages on Extracorporeal Membrane Oxygenation: Differences Between COVID-19 and Other Viral Acute Respiratory Distress Syndrome
Seeliger B, Doebler M, Hofmaenner DA, et al. Critical Care Medicine

Does Unprecedented ICU Capacity Strain, As Experienced During the COVID-19 Pandemic, Impact Patient Outcome?
Wilcox EM, Rowan KM, Harrison DA, et al. Critical Care Medicine

Aberrant Fibrin Clot Structure Visualized Ex Vivo in Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Brubaker LS, Saini A, Nguyen TC, et al. Critical Care Medicine

High-Flow Nasal Cannula in COVID-19 Pneumonia: Practical Issues
Laserna A, Barahona-Correa JE, Papadakos P, et al. Critical Care Medicine

The authors reply
Burnim MS, Wang K, Checkley W, et al. Critical Care Medicine

Vasoplegic Shock Represents a Dominant Hemodynamic Profile of Multisystem Inflammatory Syndrome Following COVID-19 in Children and Adolescents
Alali A, O’Neil E, Anders M, et al. Pediatric Critical Care Medicine

Extracorporeal Immunomodulation Treatment and Clinical Outcomes in ICU COVID-19 Patients
Yessayan LT, Neyra JA, Westover AJ, et al. Critical Care Explorations

The PANDORA Study: Prevalence and Outcome of Acute Hypoxemic Respiratory Failure in the Pre-COVID-19 Era
Villar J, Mora-Ordoñez JM, Soler JA, et al. Critical Care Explorations

Nebulized Amphotericin B in Mechanically Ventilated COVID-19 Patients to Prevent Invasive Pulmonary Aspergillosis: A Retrospective Cohort Study
Melchers M, van Zanten ARH, Heusinkveld M, et al. Critical Care Explorations

Post-Intensive Care COVID Survivorship Clinic: A Single-Center Experience
Gilmartin M, Collins J, Mason S, et al. Critical Care Explorations

Tocilizumab Versus Baricitinib in Patients Hospitalized With COVID-19 Pneumonia and Hypoxemia: A Multicenter Retrospective Cohort Study
Roddy J, Wells D, Schenck K, et al. Critical Care Explorations

Comparing Prone Positioning Use in COVID-19 Versus Historic Acute Respiratory Distress Syndrome
Hochberg CH, Psoter KJ, Sahetya SK, et al. Critical Care Explorations

Prevalence, Clinical Characteristics, and Outcomes of Sepsis Caused by Severe Acute Respiratory Syndrome Coronavirus 2 Versus Other Pathogens in Hospitalized Patients With COVID-19
Shappell CN, Klompas M, Kanjilal S, et al. Critical Care Explorations

Critical Influenza and COVID-19—A Comparative Nationwide Case-Control Study
Larsson E, Eriksson J, Eriksson M, et al. Critical Care Explorations

Effects of Prone Position on Lung Recruitment and Ventilation-Perfusion Matching in Patients With COVID-19 Acute Respiratory Distress Syndrome: A Combined CT Scan/Electrical Impedance Tomography Study
Fossali T, Pavlovsky B, Ottolina D, et al. Critical Care Medicine

Coronavirus Disease 2019 and Out-of-Hospital Cardiac Arrest: No Survivors
Baert V, Beuscart JB, Recher M, et al. Critical Care Medicine

A Retrospective Observational Study Exploring 30- and 90-Day Outcomes for Patients With COVID-19 After Percutaneous Tracheostomy and Gastrostomy Placement
Kiser SB, Sciacca K, Jain N, et al. Critical Care Medicine

Ventilator-Associated Lower Respiratory Tract Bacterial Infections in COVID-19 Compared With Non-COVID-19 Patients
Hedberg P, Ternhag A, Giske CG, et al. Critical Care Medicine

Prone Position and COVID-19: Mechanisms and Effects
Gattinoni L, Camporota L, Marini JJ. Critical Care Medicine

Resuscitation in Out-of-Hospital Cardiac Arrest Patients With COVID? Never Tell Me the Odds!
Barnicle RN, Wright BJ. Critical Care Medicine

Do Tracheostomy and Gastrostomy Confer Immortality in COVID-19?
Layba C, Wallace DJ. Critical Care Medicine

The Puzzles of Ventilator-Associated Pneumonia and COVID-19: Absolute Knowns and Relative Unknowns
Ryder JH, Kalil AC. Critical Care Medicine

Impact of the Coronavirus Disease 2019 Pandemic on Moral Distress Among Nurses and Physicians in Spanish ICUs
Rodriguez-Ruiz E, Campelo-Izquierdo M, Boga Veiras P, et al. Critical Care Medicine

Inspiratory Airway Resistance in Respiratory Failure Due to COVID-19
Nezami B, Tran HV, Zamora K, et al. Critical Care Explorations

COVID-19 Patients Require Prolonged Extracorporeal Membrane Oxygenation Support for Survival Compared With Non-COVID-19 Patients
Russ M, Menk M, Graw JA, et al. Critical Care Explorations

A Multicenter Evaluation of the Seraph 100 Microbind Affinity Blood Filter for the Treatment of Severe COVID-19
Chitty SA, Mobbs S, Rifkin BS, et al. Critical Care Explorations

Six-Month Impairment in Cognition, Mental Health, and Physical Function Following COVID-19–Associated Respiratory Failure
Maley JH, Sandsmark Dk, Trainor A, et al. Critical Care Explorations

Outcomes in Temporary ICUs Versus Conventional ICUs: An Observational Cohort of Mechanically Ventilated Patients With COVID-19–Induced Acute Respiratory Distress Syndrome
Jimenez JV, Olivas-Martinez A, Rios-Olais FA, et al. Critical Care Explorations

Role of Early Enteral Nutrition in Mechanically Ventilated COVID-19 Patients
Haines K, Parker V, Ohnuma T, et al. Critical Care Explorations

Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Patients During the First Year of the COVID-19 Pandemic
Cervantes-Arslanian AM, Venkata C, Anand P, et al. Critical Care Explorations

In Situ Pulmonary Thrombolysis and Perfusion Lung Angiography in Severe COVID-19 Respiratory Failure
Pérez-Calatayud AA, Enriquez-García R, Fareli-González C, et al. Critical Care Explorations

Use of Airway Pressure Release Ventilation in Patients With Acute Respiratory Failure Due to COVID-19: Results of a Single-Center Randomized Controlled Trial
Ibarra-Estrada, MA, García-Salas Y, Mireles-Cabodevila E, et al. Critical Care Medicine

Differences and Similarities Among COVID-19 Patients Treated in Seven ICUs in Three Countries Within One Region: An Observational Cohort Study
Mesotten DP, Meijs DAM, van Bussel BCT, et al. Critical Care Medicine

Vascular Thrombosis in Severe COVID-19 Requiring Extracorporeal Membrane Oxygenation: A Multicenter Study
Weir-McCall JR, Galea G, Mun Mak S, et al. Critical Care Medicine

Prone Position in COVID-19 and -COVID-19 Acute Respiratory Distress Syndrome: An International Multicenter Observational Comparative Study
Camporota L, Sanderson B, Chiumello D, et al. Critical Care Medicine

Influence of Geopolitics on Severity and Outcome in COVID-19
Bauer, PR. Critical Care Medicine

Phenotypic Characterization of Right Ventricular Dysfunction and Prognostication in COVID-19–Induced Acute Respiratory Distress Syndrome
Jha AK, Jha N. Critical Care Medicine

The authors reply
Chotalia M, Ali M, Alderman J, et al. Critical Care Medicine

Etiopathogenetic Particularities and Prognostic Impact of Right Ventricular Involvement in COVID-19–Related Acute Respiratory Distress Syndrome
Dandel M. Critical Care Medicine

The authors reply
Chotalia M, Ali M, Alderman J, et al. Critical Care Medicine

Airway Pressure Release Ventilation in Acute Respiratory Failure Due to COVID-19: When One Door Closes
Ghosh AJ, Nieman GF, Habshi NM. Critical Care Medicine

I Cannot Let It Go
Dewan M. Pediatric Critical Care Medicine

The Third Wave: Comparing Seasonal Trends in COVID-19 Patient Data at a Large Hospital System in New York City
Tandon P, Leibner ES, Hackett A, et al. Critical Care Explorations

Albumin Kinetics in Sepsis and COVID-19
Siddiqui SS, Chakraborty N, Muzaffar SN, et al. Critical Care Explorations

Increasing Mortality in Venovenous Extracorporeal Membrane Oxygenation for COVID-19–Associated Acute Respiratory Distress Syndrome
Braaten JA, Bergman ZR, Wothe JK, et al. Critical Care Explorations

Characteristics of Post-ICU and Post-COVID Recovery Clinics in 29 U.S. Health Systems
Danesh V, Boehm LM, Eaton TL, et al. Critical Care Explorations

Mortality Among Noncoronavirus Disease 2019 Critically Ill Patients Attributable to the Pandemic in France
Payet C, Polazzi S, Rimmelé T, et al. Critical Care Medicine

Body Mass Index and Mortality in Coronavirus Disease 2019 and Other Diseases: A Cohort Study in 35,506 ICU Patients
Kooistra EJ, Brinkman S, van der Voort PHJ, et al. Critical Care Medicine

Characterization and Outcomes of Hospitalized Children With Coronavirus Disease 2019: A Report From a Multicenter, Viral Infection and Respiratory Illness Universal Study (Coronavirus Disease 2019) Registry
Bhalala US, Gist KM, Tripathi S, et al. Critical Care Medicine

Thrombocytopenia After Coronavirus Disease 2019 Vaccination: Remember to Put the Blame on Others Too
De Bruyne S, Degandt S, Ghys T, Louagie H. Critical Care Medicine

Coronavirus Disease-Induced Blurred Judgment
Bedeir K. Critical Care Medicine

Coronavirus Disease 2019 Temperature Trajectories Correlate With Hyperinflammatory and Hypercoagulable Subphenotypes
Bhavani SV, Verhoef PA, Maier CL, et al. Critical Care Medicine

Trends in ICU Mortality From Coronavirus Disease 2019: A Tale of Three Surges
Auld SC, Harrington KRV, Adelman MW. Critical Care Medicine

Long-Term Acute Care Hospital Outcomes of Mechanically Ventilated Patients With Coronavirus Disease 2019
Saad M, Laghi FA Jr, Brofman J, et al. Critical Care Medicine

Beneficial Effect of Prone Positioning During Venovenous Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019
Zaaqoq AM, Barnett AG, Griffee MJ, et al. Critical Care Medicine

The Role of the Long-Term Acute Care Hospital Following Critical Illness—Has the Coronavirus Disease 2019 Pandemic Demonstrated Their Usefulness or Emphasized Their Downside?
Morgan P. Critical Care Medicine

Right Ventricular Dysfunction and Its Association With Mortality in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome: Do Not Focus on Not Reliable Markers!
Petit M, Bidar F. Critical Care Medicine

The Intriguing, Still Undercovered, Clinical Role of Echocardiography in Critically Ill Coronavirus Disease Patients
Lazzeri C, Bonizzoli M, Peris A. Critical Care Medicine

Association Between Pandemic Coronavirus Disease 2019 Public Health Measures and Reduction in Critical Care Utilization Across ICUs in Alberta, Canada
Bagshaw SM, Zuege DJ, Stelfox HT, et al. Critical Care Medicine

Prognostic and Predictive Biomarkers in Patients With Coronavirus Disease 2019 Treated With Tocilizumab in a Randomized Controlled Trial
Tom J, Bao M, Tsai L, et al. Critical Care Medicine

The Coronavirus Disease 2019 Pandemic Impacts Burnout Syndrome Differently Among Multiprofessional Critical Care Clinicians—A Longitudinal Survey Study
Moll V, Meissen H, Pappas S, et al. Critical Care Medicine

Increased Incidence of Ventilator-Acquired Pneumonia in Coronavirus Disease 2019 Patients: A Multicentric Cohort Study
Vacheron CH, Lepape A, Savey A, et al. Critical Care Medicine

Barotrauma in Coronavirus Disease 2019 Patients Undergoing Invasive Mechanical Ventilation: A Systematic Literature Review
Belletti A, Todaro G, Valsecchi G, et al. Critical Care Medicine

Is Ventilator-Associated Pneumonia More Frequent in Patients With Coronavirus Disease 2019?
KalilA, Cawcutt KA. Critical Care Medicine

Bursting at the Seams: Barotrauma in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Patients
Hossain S, Pastores S. Critical Care Medicine

The Effectiveness of High-Flow Nasal Cannula in Coronavirus Disease 2019 Pneumonia: A Retrospective Cohort Study
Burnim MS, Wang K, Checkley W, et al. Critical Care Medicine

Coronavirus Disease 2019 Tracheostomy Candidacy, Ceteris Paribus Assumptions, and Tracking Survivorship Data
Brenner MJ, Feller-Kopman DJ, Pelosi P. Critical Care Medicine

Brief Report: Rapid Clinical Recovery From Critical Coronavirus Disease 2019 With Respiratory Failure in a Pregnant Patient Treated With IV Vasoactive Intestinal Peptide
Youssef JG, Bitar MZ, Zahiruddin F, et al. Critical Care Explorations

Serial Thromboelastography and the Development of Venous Thromboembolism in Critically Ill Patients With COVID-19
Marvi TK, Stubblefield WB, Tillman BF, et al. Critical Care Explorations

Functionality of Scarce Healthcare Resource Triage Teams During the COVID-19 Pandemic: A Multi-Institutional Simulation Study
Butler CR, Webster LB, Sakata VL, et al. Critical Care Explorations

Characteristics and Outcomes of Patients With Frailty Admitted to ICU With Coronavirus Disease 2019: An Individual Patient Data Meta-Analysis
Subramaniam A, Anstey C, Curtis JR, et al. Critical Care Explorations

Abnormal Right Ventricular Free Wall Strain Prior to Prone Ventilation May Be Associated With Worse Outcome of Patients With COVID-19–Associated Acute Respiratory Distress Syndrome
Temperikidis P, Koroneos A, Xourgia E, et al. Critical Care Explorations

In COVID-19 Patients Who Suffer In-Hospital Cardiac Arrest, Cardiopulmonary Resuscitation Outcomes May Be Impacted by Arrest Etiology and Local Pandemic Conditions
Murphy CG, Nishikawa MS, Char ST, et al. Critical Care Explorations

Impaired Microvascular Function in Patients With Critical COVID-19
Gille-Johnson P, Kessler I, Tehrani S. Critical Care Explorations

Augmented Renal Clearance: An Under-Recognized Phenomenon Associated With COVID-19
Rhoney DH, Brooks AB, Nelson NR. Critical Care Explorations

Proning in COVID-19 Acute Respiratory Distress Syndrome: Role of Paralytics
Cotton SA, McGuire WC, Hussain A, et al. Critical Care Explorations

Hospital Variation in Management and Outcomes of Acute Respiratory Distress Syndrome Due to COVID-19
Johnson SW, Garcia MA, Sisson EKQ, et al. Critical Care Explorations

Clinical and Histopathologic Features of Myocarditis in Multisystem Inflammatory Syndrome (Adult)–Associated COVID-19
Aldeghaither S, Qutob R, Assanangkornchai N, et al. Critical Care Explorations

One-Year Outcomes of Postintensive Care Syndrome in Critically Ill Coronavirus Disease 2019 Patients: A Single Institutional Study
Banno A, Hifumi T, Takahashi Y, et al.  Critical Care Explorations

Altered Heart Rate Variability Early in ICU Admission Differentiates Critically Ill Coronavirus Disease 2019 and All-Cause Sepsis Patients
Kamaleswaran R, Sadan O, Kandiah P, et al. Critical Care Explorations

Immunothrombosis Biomarkers for Distinguishing Coronavirus Disease 2019 Patients From Noncoronavirus Disease Septic Patients With Pneumonia and for Predicting ICU Mortality
Cani E, Dwivedi D,  Liaw K-L, et al. Critical Care Explorations

Evaluation of Albumin Kinetics in Critically Ill Patients With Coronavirus Disease 2019 Compared to Those With Sepsis-Induced Acute Respiratory Distress Syndrome
Su C, Hoffman KL,  Xu Z, et al. Critical Care Explorations

Caring for Unvaccinated Patients in the ICU: Beyond Frustration, Toward Beneficial Relationships
Bibler TM, Nelson RH, Schuman O, Miller SM. Critical Care Explorations

Identification of Aggravation-Predicting Gene Polymorphisms in Coronavirus Disease 2019 Patients Using a Candidate Gene Approach Associated With Multiple Phase Pathogenesis: A Study in a Japanese City of 1 Million People
Tanimine N, Takei D, Tsukiyama N, et al. Critical Care Explorations

Assessment of 28-Day In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019: An International Cohort Study
Li Bassi G, Suen JY, White N, et al. Critical Care Explorations

Recognizing Vaccine-Induced Immune Thrombotic Thrombocytopenia
Iba T, Levy JH, Warkentin TE. Critical Care Explorations

Plasma Soluble CD14 Subtype Levels Are Associated With Clinical Outcomes in Critically Ill Subjects With Coronavirus Disease 2019
Mabrey FL, Morrell ED, Bhatraju PK, et al. Critical Care Explorations

Mini-Bronchoalveolar Lavage for Diagnosing Coronavirus Disease 2019–Associated Invasive Pulmonary Aspergillosis
Vanbellinghen MC, Atasever B, van der Spoel HJI, et al. Critical Care Explorations

Variation in Use of Repurposed Medications Among Patients With Coronavirus Disease 2019. From The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study: Coronavirus Disease 2019 Registry Investigator Group
Garcia MA, Johnson SW, Bosch NA, et al. Critical Care Explorations

Assessment of 28-Day In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019: An International Cohort Study
Li Bassi G, Suen JY, White N, et al. Critical Care Explorations

Identification of Aggravation-Predicting Gene Polymorphisms in Coronavirus Disease 2019 Patients Using a Candidate Gene Approach Associated With Multiple Phase Pathogenesis: A Study in a Japanese City of 1 Million People
Tanimine N, Takei D, Tsukiyama N, et al. Critical Care Explorations

Multisystem Inflammation and Organ Dysfunction After BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccination
Kahn B, Apostolidis, Sokratis SA, Bhatt V, et al. Critical Care Explorations

Is Ventilator-Associated Pneumonia More Frequent in Patients With Coronavirus Disease 2019?
Kalil AC, Cawcutt KA. Critical Care Medicine

I Cannot Let It Go
Dewan M. Pediatric Critical Care Medicine

Dorsal Push and Abdominal Binding Improve Respiratory Compliance and Driving Pressure in Proned Coronavirus Disease 2019 Acute Respiratory Distress Syndrome
Elmufdi FS, Marini JJ. Critical Care Explorations

Some Patients Are More Equal Than Others: Variation in Ventilator Settings for Coronavirus Disease 2019 Acute Respiratory Distress Syndrome
Dam TA. de Grooth HJ,  Klausch T, et al. Critical Care Explorations

Interhospital Transfer Outcomes for Critically Ill Patients With Coronavirus Disease 2019 Requiring Mechanical Ventilation
Chen E, Longcoy J, McGowan SK, et al. Critical Care Explorations

A Modified Delphi Process to Prioritize Experiences and Guidance Related to ICU Restricted Visitation Policies During the Coronavirus Disease 2019 Pandemic
Fiest KM, Krewulak KD, Makuk K, et al. Critical Care Explorations

The Role of a Statewide Critical Care Coordination Center in the Coronavirus Disease 2019 Pandemic—and Beyond
Galvagno SM, Naumann A, Delbridge TR, et al. Critical Care Explorations

Respiratory Non-Invasive Venous Waveform Analysis for Assessment of Respiratory Distress in Coronavirus Disease 2019 Patients: An Observational Study
Alvis B, Vaughn L, Schmeckpeper J, et al. Critical Care Explorations

Patients With Coronavirus Disease 2019 Requiring Invasive Mechanical Ventilation in Mexico in the First, Second, and Exponential Growth Phase of the Third Wave of the Coronavirus Disease 2019 Pandemic
Ñamendys-Silva SA. Critical Care Explorations

Fewer Intubations but Higher Mortality Among Intubated Coronavirus Disease 2019 Patients During the Second Than the First Wave
Routsi C, Kokkoris S, Siempos I, et al. Critical Care Explorations

ICU Mortality in Patients With Coronavirus Disease 2019 Infection: Highlighting Healthcare Disparities in Rural Appalachia
Sharma S, Badami V, Rojas E, et al. Critical Care Explorations

End-of-Life Care During the Coronavirus Disease 2019 Pandemic: The 3 Wishes Program
Neville TH, Bear DK, Kao Y, et al. Critical Care Explorations

Prognostic and Predictive Biomarkers in Patients With Coronavirus Disease 2019 Treated With Tocilizumab in a Randomized Controlled Trial
Tom J, Bao M, Tsai L, et al. Critical Care Medicine

Differences and Similarities Among Coronavirus Disease 2019 Patients Treated in Seven ICUs in Three Countries Within One Region: An Observational Cohort Study
Mesotten D, Meijs DAM, van Bussel BCT, et al. Critical Care Medicine

Effectiveness of High-Flow Nasal Cannula in Coronavirus Disease 2019 Pneumonia: A Retrospective Cohort Study
Burnim M, Kunbo W, Checkley W, et al. Critical Care Medicine

Characterization and Outcomes of Hospitalized Children With Coronavirus Disease 2019: A Report From a Multicenter, Viral Infection and Respiratory Illness Universal Study (Coronavirus Disease 2019) Registry
Bhalala US, Gist KM, Tripathi S, et al. Critical Care Medicine

Vascular Thrombosis in Severe Coronavirus Disease 2019 Requiring Extracorporeal Membrane Oxygenation: A Multicenter Study
Weir-McCall JR, Galea G, Mun Mak S, et al. Critical Care Medicine

Beneficial Effect of Prone Positioning During Venovenous Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019
Zaaqoq AM, Barnett AG, Griffee MJ, et al. Critical Care Medicine

Prone Position in Coronavirus Disease 2019 and Noncoronavirus Disease 2019 Acute Respiratory Distress Syndrome: An International Multicenter Observational Comparative Study
Camporota L, Sanderson B, Chiumello D, et al. Critical Care Medicine

Increased Incidence of Ventilator-Acquired Pneumonia in Coronavirus Disease 2019 Patients: A Multicentric Cohort Study
Vacheron CH, Lepape A, Savey A, et al. Critical Care Medicine

The Coronavirus Disease 2019 Pandemic Impacts Burnout Syndrome Differently Among Multiprofessional Critical Care Clinicians—A Longitudinal Survey Study
Moll V, Meissen H, Pappas S, et al. Critical Care Medicine

Barotrauma in Coronavirus Disease 2019 Patients Undergoing Invasive Mechanical Ventilation: A Systematic Literature Review
Belletti A, Todaro G, Valsecchi G, et al. Critical Care Medicine

Accelerating Coronavirus Disease 2019 Therapeutic Interventions and Vaccines—Selecting Compounds for Clinical Evaluation in Coronavirus Disease 2019 Clinical Trials
Buchman TG, Draghia-Akli, R, Adam SJ, et al. Critical Care Medicine

Thrombocytopenia After Coronavirus Disease 2019 Vaccination: Remember to Put the Blame on Others Too
De Bruyne S, Degandt S, Ghys T, et al. Critical Care Medicine

Coronavirus Disease 2019 Tracheostomy Candidacy, Ceteris Paribus Assumptions, and Tracking Survivorship Data
Brenner MJ, Feller-Kopman DJ, Pelosi, P. Critical Care Medicine

Interleukin-6 in Critical Coronavirus Disease 2019, a Driver of Lung Inflammation of Systemic Origin?
Araskog NR, Aass HC, Holter JC, et al. Critical Care Explorations

Plasma Exchange in Patients With Severe Coronavirus Disease 2019: A Single-Center Experience
Nusshag C, Morath C, Speer C, et al.   Critical Care Explorations

Bronchoscopy During Coronavirus Disease 2019 Pandemic: A Bronchoscopist’s Perspective
Saha BK, Chaudhary R, Saha S, et al.  Critical Care Explorations

Clinical Characteristics, Management, and Outcomes of Cancer Patients With Coronavirus Disease 2019 Admitted to the ICU
Dang KM, Bhatt I, Dulu AO, et al.  Critical Care Explorations

Comparison of Published Guidelines for the Diagnosis and the Management of Vaccine-Induced Immune Thrombotic Thrombocytopenia
Zazzeron L, Rosovsky RP, Bittner EA, et al.  Critical Care Explorations

Argatroban for Anticoagulation in Patients Requiring Venovenous Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019
Sattler LA, Boster JM, Ivins-O’Keefe KM, et al.  Critical Care Explorations

One-Year Functional, Cognitive, and Psychological Outcomes Following the Use of Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019: A Prospective Study
Rajajee V, Fung CM-C, Seagly KS, et al.  Critical Care Explorations

Online Letter to the Editor: Right Ventricular Dysfunction and Its Association With Mortality in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome: Do Not Focus on Not Reliable Markers!
Petit M, Bidar F.  Critical Care Medicine

Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry
Tripathi S, Sayed IA, Dapul H, et al. Critical Care Explorations

Machine Learning Prediction of Death in Critically Ill Patients With Coronavirus Disease 2019
Churpek MM, Gupta S, Spicer AB, et al. Critical Care Explorations

Safety and Feasibility of an Interdisciplinary Treatment Approach to Optimize Recovery From Critical Coronavirus Disease 2019
Mayer KP, Parry SM, Kalema AG, et al. Critical Care Explorations

Adherence to Lung Protective Ventilation in Patients With Coronavirus Disease 2019
Levy E, Scott S, Tran T, et al. Critical Care Explorations

Psychologic Distress and Quality of Life After ICU Treatment for Coronavirus Disease 2019: A Multicenter, Observational Cohort Study
Vlake JH, Van Bommel J, Hellemons ME, et al. Critical Care Explorations

Online Letter to the Editor: Coronavirus Disease-Induced Blurred Judgment
Bedeir K. Critical Care Medicine

Defining Potential Therapeutic Targets in Coronavirus Disease 2019: A Cross-Sectional Analysis of a Single-Center Cohort
Arulkumaran N, Snow TAC, Kulkarni A, et al. Critical Care Explorations

Editorial: Bursting at the Seams: Barotrauma in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Patients
Hossain S, Pastores SM. Critical Care Medicine

Online Letter to the Editor: The Intriguing, Still Undercovered, Clinical Role of Echocardiography in Critically Ill Coronavirus Disease Patients
Lazzeri C, Bonizzoli M, Peris A. Critical Care Medicine

Characterization and Outcomes of Hospitalized Children With Coronavirus Disease 2019: A Report From a Multicenter, Viral Infection and Respiratory Illness Universal Study (Coronavirus Disease 2019) Registry
Bhalala US, Gist KM, Tripathi S, et al. Critical Care Medicine

Methylprednisolone and 60 Days in Hospital Survival in Coronavirus Disease 2019 Pneumonia
Go RC, Shah R, Nyirenda T, et al. Critical Care Explorations

Cardiopulmonary Exercise Testing in Critically Ill Coronavirus Disease 2019 Survivors: Evidence of a Sustained Exercise Intolerance and Hypermetabolism
Joris M, Minguet P, Colson C, et al. Critical Care Explorations 

Performance Analysis of the National Early Warning Score and Modified Early Warning Score in the Adaptive COVID-19 Treatment Trial Cohort
Colombo CJ, Colombo RE, Maves RC, et al. Critical Care Explorations

Pharmacotherapy in Coronavirus Disease 2019 and Risk of Secondary Infections: A Single-Center Case Series and Narrative Review
Behal M, Barlow B, Mefford B, et al. Critical Care Explorations

Case Report: Interleukin-7 Reverses Lymphopenia and Improves T-Cell Function in Coronavirus Disease 2019 Patient With Inborn Error of Toll-Like Receptor 3
Mazer MB, Turnbull IR, Miles S, et al. Critical Care Explorations

Empirical Assessment of U.S. Coronavirus Disease 2019 Crisis Standards of Care Guidelines
Bharadwaj M, Jezmir JL, Kishore SP, et al. Critical Care Explorations

Awake Venovenous Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019 Acute Respiratory Failure
Assanangkornchai N, Slobod D, Qutob R, et al. Critical Care Explorations

Trends in 28-Day Mortality of Critical Care Patients With Coronavirus Disease 2019 in United Kingdom
Dennis JM, McGovern AP, Thomas NJ, et al. Critical Care Medicine

Coronavirus Disease 2019 as Cause of Viral Sepsis: A Systematic Review and Meta-Analysis
Karakike E, Giamarellos-Bourboulis EJ, Kyprianou M, et al. Critical Care Medicine

Editorial: Quantifying the Burden of Viral Sepsis During the Coronavirus Disease 2019 Pandemic and Beyond
Shappell CN, Klompas M, Rhee C. Critical Care Medicine

Long-Term Acute Care Hospital Outcomes of Mechanically Ventilated Patients With Coronavirus Disease 2019
Saad M, Laghi FA Jr, Brofman J, et al. Critical Care Medicine

Editorial: The Role of the Long-Term Acute Care Hospital Following Critical Illness—Has the Coronavirus Disease 2019 Pandemic Demonstrated Their Usefulness or Emphasized Their Downside?
Morgan P. Critical Care Medicine

Trends in ICU Mortality From Coronavirus Disease 2019: A Tale of Three Surges
Auld SC, Harrington KRV, Adelman MW, et al. Critical Care Medicine

Ischemic and Hemorrhagic Stroke Among Critically Ill Patients With Coronavirus Disease 2019: An International Multicenter Coronavirus Disease 2019 Critical Care Consortium Study
Cho S-M, Premraj L, Fanning J, et al. Critical Care Medicine

Body Mass Index and Mortality in Coronavirus Disease 2019 and Other Diseases: A Cohort Study in 35,506 ICU Patients
Kooistra EJ, Brinkman S, van der Voort PHJ, et al. Critical Care Medicine

Mortality Among Noncoronavirus Disease 2019 Critically Ill Patients Attributable to the Pandemic in France
Payet C, Polazzi S, Rimmelé T, Duclos A. Critical Care Medicine

Online Letter to the Editor: Higher Than Expected Severity-Adjusted Mortality in ICU Patients With Coronavirus Disease 2019: Time to Consider the Contributions of Pandemic-Related Transformations in Structure and Process
Oud L. Critical Care Medicine

Letter to the Editor: Lung Abscess in Critically Ill Coronavirus Disease 2019 Patients With Ventilator-Associated Pneumonia: A French Monocenter Retrospective Study
Beaucoté V, Plantefève G, Tirolien J-A, et al. Critical Care Explorations

Soluble Suppression of Tumorigenicity-2 Associates With Ventilator Dependence in Coronavirus Disease 2019 Respiratory Failure
Alladina JW, Giacona GL, White EB, et al. Critical Care Explorations

Editorial: Prone Positioning in Coronavirus Disease 2019: Just Do It!
Dembinski R. Critical Care Medicine

Tracheostomy for Coronavirus Disease 2019 Patients on Mechanical Ventilation Should Not Be Arbitrarily Delayed
Appavu SK. Critical Care Medicine

Technology and Disasters: The Evolution of the National Emergency Tele-Critical Care Network
Pamplin JC, Scott BK, Quinn MT, et al. Critical Care Medicine

Scarce Resource Allocation in a Pandemic: A Protocol to Promote Equity, Timeliness, and Transparency
Lynch JF, Perera IM, Iwashyna TJ. Critical Care Explorations

Examination of Early CNS Symptoms and Severe Coronavirus Disease 2019: A Multicenter Observational Case Series
Marra DE, Busl KM, Robinson CP, et al. Critical Care Explorations

Epidemiological and Clinical Characterization of Superinfections in Critically Ill Coronavirus Disease 2019 Patients
Signorini L, Moioli G, Calza S, et al. Critical Care Explorations

Operationalizing Ethical Guidance for Ventilator Allocation in Minnesota: Saving the Most Lives or Exacerbating Health Disparities?
Kesler SM, Wu JT, Kalland KR, et al. Critical Care Explorations

Validation of a Crisis Standards of Care Model for Prioritization of Limited Resources During the Coronavirus Disease 2019 Crisis in an Urban, Safety-Net, Academic Medical Center
Nadjarian A, LeClair J, Mahoney TF, et al. Critical Care Medicine

Impact of Nonpharmaceutical Interventions on ICU Admissions During Lockdown for Coronavirus Disease 2019 in New Zealand—A Retrospective Cohort Study
Gonzenbach TP, Mc Guinness SP, Parke RL, et al. Critical Care Medicine

Respiratory Physiology of Prone Positioning With and Without Inhaled Nitric Oxide Across the Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Severity Spectrum
Ziehr DR, Alladina J, Wolf ME, et al. Critical Care Explorations

Early Intubation and Increased Coronavirus Disease 2019 Mortality: A Propensity Score–Matched Retrospective Cohort Study
Parish AJ, West JR, Caputo ND, et al. Critical Care Explorations

Using Nonheparin Anticoagulant to Treat a Near-Fatal Case With Multiple Venous Thrombotic Lesions During ChAdOx1 nCoV-19 Vaccination-Related Vaccine-Induced Immune Thrombotic Thrombocytopenia
Bersinger S, Lagarde K, Marlu R, et al. Critical Care Medicine

Return to Work After Coronavirus Disease 2019 Acute Respiratory Distress Syndrome and Intensive Care Admission: Prospective, Case Series at 6 Months From Hospital Discharge
Carenzo L, Dalla Corte F, Haines RW, et al. Critical Care Medicine

Endothelial Dysfunction as a Component of Severe Acute Respiratory Syndrome Coronavirus 2–Related Multisystem Inflammatory Syndrome in Children With Shock
Borgel D, Chocron R, Grimaud M, et al. Critical Care Medicine

Editorial: Utility of Coronavirus Disease 2019 Immune Profiling for the Clinician at the Bedside
Minkove SJ, Torabi-Parizi P. Critical Care Medicine

Editorial: Coronavirus Disease 2019: There Is a Heart Between the Lungs
Michard F, Gonzalez F. Critical Care Medicine

Editorial: The Long Road to Normalcy Following Survival From COVID-19–Associated Acute Respiratory Distress Syndrome
Suffredini DA. Critical Care Medicine

Editorial Glucocorticoid-Glucocorticoid Receptor Response to Severe Acute Respiratory Syndrome Coronavirus 2
Annane D, Godot V. Critical Care Medicine

Online Letter to Editor: Optimal Patient Selection for the Prophylactic Anticoagulation Therapy in Patients With Coronavirus Disease 2019
Nishioka A. Imamura T. Critical Care Medicine

Online Letter to the Editor: The Janus Face of Coronavirus Disease 2019–Associated Coagulopathy
Stahl K, Seeliger B, Hofmaenner DA, et al. Critical Care Medicine

Online Letter to the Editor: Reasons for the Overuse of Sedatives and Deep Sedation for Mechanically Ventilated Coronavirus Disease 2019 Patients
Xiao Z, Zhao L. Critical Care Medicine

Optimal Management of Thrombotic Complications in Patients With Coronavirus Disease 2019
Imamura T. Critical Care Medicine

Development and Validation of ARC, a Model for Anticipating Acute Respiratory Failure in Coronavirus Disease 2019 Patients
Saria S, Schulam P, Yeh BJ, et al. Critical Care Explorations

Awake Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019 Patients Without Invasive Mechanical Ventilation
Azzam MH, Mufti HN, Bahaudden H, et al. Critical Care Explorations

Online Letter to the Editor: Postcoronavirus Disease Chronic Fatigue Is Frequent and Not Only Restricted to Hospitalized Patients
Reuken PA, Scherag A, Stallmach A. Critical Care Medicine

Editorial: Advancing Telehealth-Based Screening for Postintensive Care Syndrome: A Coronavirus Disease 2019 Paradigm Shift
Scheunemann LP, Girard TD. Critical Care Medicine

Editorial: Do Our Sedation Practices Contribute to Increased Mortality in Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome?
Devlin JW, Pandharipande PP. Critical Care Medicine
 
Increased Glucocorticoid Receptor Alpha Expression and Signaling in Critically Ill Coronavirus Disease 2019 Patients
Vassiliou AG, Athanasiou N, Keskinidou C, et al. Critical Care Medicine
 
Coronavirus Disease 2019: A Pandemic Spawning an Infodemic
Remy KE, Kissoon N. Pediatric Critical Care Medicine

Is Microthrombosis the Main Pathology in Coronavirus Disease 2019 Severity?—A Systematic Review of the Postmortem Pathologic Findings
Fahmy OH, Daas FM, Salunkhe V, et al. Critical Care Explorations

Letter to the Editor: Less Lumping and More Splitting: Why We Should Not Call COVID Sepsis
Oxman DA. Critical Care Medicine

Outcome Improvement Between the First Two Waves of the Coronavirus Disease 2019 Pandemic in a Single Tertiary-Care Hospital in Belgium
Lambermont B, Rousseau A-F, Seidel L, et al. Critical Care Explorations

Comparison of Circulating Immune Cells Profiles and Kinetics Between Coronavirus Disease 2019 and Bacterial Sepsis
de Roquetaillade C, Mansouri S, Brumpt C, et al. Critical Care Medicine

A High Neutrophil-Lymphocyte Ratio Is Associated With Increased Morbidity and Mortality in Patients With Coronavirus Disease 2019
King AH, Mehkri O, Rajendram P, et al. Critical Care Explorations

A Multicenter Evaluation of Survival After In-Hospital Cardiac Arrest in Coronavirus Disease 2019 Patients
Bhardwaj A, Alwakeel M, Saleem T, et al. Critical Care Explorations

Letter to the Editor: Cytokine Blockade in Coronavirus Disease 2019: Keeping an Open Mind
Szakmany T, Duric N, Champanerkar S, et al. Critical Care Explorations

Timing of Intubation in Coronavirus Disease 2019: A Study of Ventilator Mechanics, Imaging, Findings, and Outcomes
Bavishi AA, Mylvaganam RJ, Agarwal R, et al. Critical Care Explorations

Characteristics, Comorbidities, Complications, and Outcomes Among 802 Patients With Severe Acute Respiratory Syndrome Coronavirus 2 in a Community Hospital in Florida
Patel SR, Mukkera SR, Tucker L et al. Critical Care Explorations

Coronavirus Disease 2019–Associated PICU Admissions: A Report From the Society of Critical Care Medicine Discovery Network Viral Infection and Respiratory Illness Universal Study Registry
Tripathi S, Gist KM, Bjornstad EC, et al. Pediatric Critical Care Medicine

Functional Outcomes and Their Association With Physical Performance in Mechanically Ventilated Coronavirus Disease 2019 Survivors at 3 Months Following Hospital Discharge: A Cohort Study
van Gassel RJJ, Bels J, Remij L, et al. Critical Care Medicine

Prone Positioning of Nonintubated Patients With Coronavirus Disease 2019—A Systematic Review and Meta-Analysis
Ponnapa Reddy M, Subramaniam A, Afroz A, et al. Critical Care Medicine

Existing Crisis Standards of Care Triage Protocols May Not Significantly Differentiate Between Patients With Coronavirus Disease 2019 Who Require Intensive Care
Rubin EB, Knipe RS, Israel RA, et al. Critical Care Explorations

Frugal Innovation: Enabling Mechanical Ventilation During Coronavirus Disease 2019 Pandemic in Resource-Limited Settings
Dave C, Cameron P, Basmaji J, et al. Critical Care Explorations

Determining Cause of Death During Coronavirus Disease 2019 Pandemic
Nada KM, Hsu E-s, Seashore J, et al. Critical Care Explorations

Letter to the Editor: Bias Due to Cohort Construction in the Study of Timing of Invasive Ventilation
Yarnell CJ, Munshi L. Critical Care Explorations