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Surviving Sepsis Campaign Guidelines 2021
Citation: Critical Care Medicine: October 4, 2021
International Guidelines for Management of Sepsis and Septic Shock 2021
Updated global adult sepsis guidelines, released in October 2021 by the Surviving Sepsis Campaign (SSC), place an increased emphasis on improving the care of sepsis patients after they are discharged from the intensive care unit (ICU) and represent greater geographic and gender diversity than previous versions.
The new guidelines specifically address the challenges of treating patients experiencing the long-term effects of sepsis. Patients often experience lengthy ICU stays and then face a long, complicated road to recovery. In addition to physical rehabilitation challenges, patients and their families are often uncertain how to coordinate care that promotes recovery and matches their goals of care.
To address these issues, the guidelines recommend involving patients and their families in goals-of-care discussions and hospital discharge plans, which should include early and ongoing follow-up with clinicians to support and manage long-term effects and assessment of physical, cognitive, and emotional issues after discharge.
Guideline Type: Clinical
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We make no recommendation on the use of antiviral agents.
There is insufficient evidence to make a recommendation on the use of restrictive versus liberal fluid strategies in the first 24 hours of resuscitation in patients with sepsis and septic shock who still have signs of hypoperfusion and volume depletion after the initial resuscitation.
There is insufficient evidence to make a recommendation on the use of conservative oxygen targets in adults with sepsis-induced hypoxemic respiratory failure.
There is insufficient evidence to make a recommendation on the use of noninvasive ventilation compared to invasive ventilation for adults with sepsis-induced hypoxemic respiratory failure.
There is insufficient evidence to make a recommendation on the use of other blood purification techniques.
For adults with sepsis or septic shock, there is insufficient evidence to make a recommendation on any specific standardized criterion to trigger a goals-of-care discussion.
For adults with sepsis or septic shock, there is insufficient evidence to make a recommendation on the use of any specific structured handoff tool over usual handoff processes.
For adults with sepsis or septic shock and their families, there is insufficient evidence to make a recommendation on early post-hospital discharge follow-up compared with routine post-hospital discharge follow-up.
For adults with sepsis or septic shock, there is insufficient evidence to make a recommendation for or against early cognitive therapy.
A complete list of the guidelines authors and contributors is available within the published manuscript.
