Ludwig Lin, MD, speaks with Lars O. Hoiseth, MD, about the article “Tissue Oxygen Saturation and Finger Perfusion Index in Central Hypovolemia: Influence of Pain,” published in Critical Care Medicine. Dr. Hoiseth is an Anesthesiologist at Oslo University Hospital and Faculty of Medicine at the University of Oslo in Oslo, Norway. In this article, the authors explore the effects of hypovolemia and pain on tissue oxygen saturation and finger photoplethysmographic perfusion index.