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Category: Sepsis

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How have sepsis protocols or bundles been used in COVID-19 patients and what is the best way to navigate these bundles, especially regarding fluids?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021

Altered Heart Rate Variability Early in ICU Admission Differentiates Critically Ill Coronavirus Disease 2019 and All-Cause Sepsis Patients

From Critical Care Explorations  In this descriptive statistical study, heart rate variability measures were found to be statistically different across critically ill patients infected with severe acute respiratory syndrome coronavirus 2 and distinct from bacterial sepsis.

Immunothrombosis Biomarkers for Distinguishing Coronavirus Disease 2019 Patients From Noncoronavirus Disease Septic Patients With Pneumonia and for Predicting ICU Mortality

From Critical Care Explorations  This hypothesis-generating study suggests that the pathophysiology of immunothrombosis differs between coronavirus disease 2019 patients and noncoronavirus disease septic patients.

Evaluation of Albumin Kinetics in Critically Ill Patients With Coronavirus Disease 2019 Compared to Those With Sepsis-Induced Acute Respiratory Distress Syndrome

From Critical Care Explorations  In this paper, the authors aimed to characterize the kinetics of serum albumin in critically ill patients with coronavirus disease 2019 compared with critically ill patients with sepsis-induced acute respiratory distress syndrome.

Diagnosis and Management of CIRCI in Critically Ill Patients (Part I)

This guideline, published by the ​Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM), is an update of the 2008 consensus statements for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in adult and pediatric patients. Crit Care Med 2017; 45(12):2078-2088

Early Identification of Sepsis: The Journey Since the Sepsis on the Wards Collaborative

This article was first published in the August 2019 issue of Critical Connections. AdventHealth Shawnee Mission in Shawnee Mission, Kansas, USA, had a unique opportunity to impact the care provided to patients with sepsis in partnership with the Surviving Sepsis Campaign’s (SSC) Sepsis on the Wards Collaborative. Three years later, building on this foundation, processes are still being streamlined to improve the care of this challenging population.

Sepsis Standard Work: Improving Compliance with Early Recognition and Management of Perinatal Sepsis

Leading sepsis experts discuss the Centers for Disease Control and Prevention's (CDC) recent sepsis Vital Signs and protocols for early recognition of maternal sepsis. This webinar was hosted by the CDC in partnership with the Society of Critical Care Medicine, the American Nurses Association, and the Association of Women's Health, Obstetric & Neonatal Nurses.

Empowering Nurses for Early Sepsis Recognition

Leading sepsis experts discuss the Centers for Disease Control and Prevention's (CDC) recent sepsis Vital Signs and protocols for early recognition of maternal sepsis. This webinar features an overview of CDC's sepsis Vital Signs report, a discussion on expanding sepsis early recognition, an overview of a pilot of sepsis early recognition, and lessons learned from implementing sepsis screening on hospital wards.

Advances in Sepsis: Protecting Patients Throughout the Lifespan

Leading sepsis experts discuss the Centers for Disease Control and Prevention's (CDC) recent sepsis Vital Signs and protocols for early recognition of maternal sepsis. This webinar discusses sepsis in acute care settings, septic shock guidelines for pediatrics, as well as sepsis in post-acute and long-term care settings.

SCCM Pod-406 Surviving Sepsis Campaign Children's Guidelines

Margaret M. Parker, MD, MCCM, and Scott L. Weiss, MD, FCCM, discuss the release of "Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children," published in the February 2020 issue of Pediatric Critical Care Medicine (Weiss S, et al. Pediatr Crit Care Med. 2020;21(2);e52-e106).

SCCM Pod-427 Severe COVID-19 and Sepsis

Severe COVID-19 infection can be a form of viral sepsis with occasionally concomitant bacterial infection. Explore the definition of sepsis and overlap with case descriptions of patients with severe COVID-19, treatment, and more. 

SCCM Pod-439 The Association Between Antibiotic Delay and Hospital Mortality

Explore the correlation between antibiotic delay and hospital mortality in patients with sepsis in this podcast.

SCCM Pod-441 Connections Between COVID-19, Sepsis, and Fluid Management

Learn about the importance of utilizing dynamic assessments of fluid responsiveness to guide treatment in patients with viral sepsis, including COVID-19, and understand how they can be used to help improve patient outcomes in sepsis patients. Host Pamela M. Peeke, MD, MPH, FACP, FACSM, is joined by Patrick Troy, MD, to discuss how only 50% of hemodynamically unstable patients are fluid responsive and that the same treatment paradigm in fluid management applies to both viral sepsis and COVID-19 patients.

SCCM Pod-450 Surviving Sepsis Campaign: Long-Term Goals of Care

Patients who survive sepsis may be left with short- and long-term problems that need to be addressed. This podcast discusses the implementation of initiatives for preventing impairments due to sepsis, challenges faced by survivors of sepsis, and difficulties of matching care to patient and family goals of care.

Surviving Sepsis Campaign Releases 2021 Adult Sepsis Guidelines

Updated global adult sepsis guidelines, released by the Surviving Sepsis Campaign (SSC), place an increased emphasis on improving the care of sepsis patients after they are discharged from the intensive care unit (ICU) and represent greater geographic and gender diversity than previous versions. The updated guidelines are especially important today, as many who are seriously ill with COVID-19 are particularly vulnerable to sepsis.

Coronavirus Disease 2019 as Cause of Viral Sepsis: A Systematic Review and Meta-Analysis

From Critical Care Medicine. The authors report that that majority of coronavirus disease 2019 patients hospitalized in the ICU meet Sepsis-3 criteria and present infection-associated organ dysfunction. 

Editorial: Quantifying the Burden of Viral Sepsis During the Coronavirus Disease 2019 Pandemic and Beyond

From Critical Care Medicine. This Editorial accompanies the article “Coronavirus Disease 2019 as a Cause of Viral Sepsis: A Systematic Review and Meta-Analysis” by Karakike et al.