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This community developed resource is a quick reference guide for utlization of various COVID-19 pharmacotherapies.
From Critical Care Medicine. In this study, the authors explored candidate prognostic and predictive biomarkers identified in retrospective observational studies (interleukin-6, C-reactive protein, lactate dehydrogenase, ferritin, lymphocytes, monocytes, neutrophils, D-dimer, and platelets) in patients with coronavirus disease 2019 pneumonia after treatment with tocilizumab, an anti–interleukin-6 receptor antibody, using data from the COVACTA trial in patients hospitalized with severe coronavirus disease 2019 pneumonia.
Stay up to date on the mass vaccination efforts in the United States with this SCCM webcast. Thought leaders will address current COVID-19 variants and vaccine efficacy and review pediatric vaccination considerations. This webcast is the second in a series of updates that SCCM is producing to better educate clinicians as vaccination efforts continue. The webinar was held on December 8, 2021.
From Critical Care Explorations. In this study the authors found that hospital variation in the use of repurposed medications varied widely across hospitals early in the pandemic and later converged with the emergence of randomized clinical trials.
Although several trials have examined in-hospital cardiac arrest (IHCA), only two trials in the past decade have examined the use of vasopressin and glucocorticoids for IHCA. Both trials found improved survival and favorable neurologic outcome with a vasopressin-epinephrine-methylprednisolone combination. Because of a lack of additional supporting evidence, neither the American nor European international guidelines have recommended this combination for IHCA. This Concise Critical Appraisal examines an article by Andersen et al that attempted to validate the results of these trials.
Is hydrocortisone for septic shock best used alone or in combination with fludrocortisone? This Concise Critical Appraisal explores a retrospective cohort study that found that treatment with hydrocortisone plus fludrocortisone led to lower rates of mortality or discharge to hospice, hospital deaths, and fewer days on vasopressors than treatment with hydrocortisone alone.
Two recent trials suggest that immune-damping drugs such as tocilizumab may reduce mortality in patients with severe COVID-19.
Although only a small number of patients hospitalized with COVID-19 present with a secondary bacterial pneumonia, a large percentage are unnecessarily treated with antibiotics. Pamela M. Peeke, MD, MPH, FACP, FACSM, is joined by George Sakoulas, MD, to discuss how physicians and hospitalists can identify when antibiotics are unnecessary for hospitalized patients with moderate to severe respiratory infections. Dr. Sakoulas is chief of infectious disease at Sharp Rees-Stealy Medical Group in San Diego, California, and an adjunct professor in the Division of Host-Microbe Systems and Therapeutics Center for Immunity, Infection, and Inflammation at the University of California San Diego School of Medicine in La Jolla, California. This podcast is sponsored by bioMĂ©rieux.
Crit Care Med 2017; 45(9):e877-e915
Are push-dose vasopressors (PDPs) safe and effective for patients with hypotension outside the operating room? This Concise Critical Appraisal covers a recent study that sought to determine whether phenylephrine and epinephrine are effective for acute hypotensive periods when PDP protocols are in place.
Crit Care Med. 2016;44(11):2079-2103
COVID-19 - - Quick Reference Chart. This chart is to be used as a rapid resource when choosing therapeutic options for treating COVID-19 patients.
Webcast participants were able to learn more about the recommendations included in the guidelines regarding infection control, laboratory diagnosis and specimens, hemodynamic support, ventilatory support
COVID-19 Guideline Resource.
Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered.
COVID-19 Guideline Resource. SCCM has released its Surviving Sepsis Campaign COVID-19 guidelines to manage critically ill adults with COVID-19 in the intensive care unit (ICU).
Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Question and Answer Webcast Series - Webcast 2 held on April 10, 2020.
This webinar discusses COVID-19 cases from the front-line at the University of Nebraska Medical Center Recorded on: April 17, 2020
Point of Care (PoC) Refresher Training. While current recommendations for respiratory support in COVID-19 support the use of the high-flow nasal cannula for hypoxia, oxygen supplementation strategies vary by institution. Make sure to follow your institution's protocols.