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Category: Pharmacology

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What is the role of ivermectin in the treatment of COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


Online Letter to the Editor: Plasmapheresis Efficiency in Coronavirus Disease 2019: More Related to What You Add and Not What You Take Away?

From Critical Care Medicine. This is an online Letter to the Editor in response to the article by Fernandez et al. “Plasma Exchange: An Effective Rescue Therapy in Critically Ill Patients With Coronavirus Disease 2019 Infection.”


Online Letter to the Editor: Is “Mega-Dose” IV Vitamin C Required for Septic and Critical Coronavirus Disease 2019 Patients?

From Critical Care Medicine. This online letter to the editor was written in response to “Reversal of the Pathophysiological Responses to Gram-Negative Sepsis by Megadose Vitamin C” by Lankadeva et al


For patients with COVID-19 being treated with intermediate- or full-dose enoxaparin, have anti-Xa levels been checked? If so, have higher-than-expected anti-Xa levels been found?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


When should furosemide be used in COVID-19 patients? Some COVID-19 patients are presenting with diarrhea rather than respiratory symptoms. Is there any evidence-based treatment for this?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


Now that patients are being vaccinated, when ruling out COVID-19 in patients who might have pneumonia or pulmonary embolism, how should their vaccination status be taken into account?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


Editorial: Do Our Sedation Practices Contribute to Increased Mortality in Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome?

From Critical Care Medicine. In this Editorial, the authors discuss the article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome” and suggest that reemploying the use of evidence-based strategies developed over the past 20 years through rigorous controlled trials is one of the best mechanisms by which to help critically ill adults with COVID-19 liberate from the ICU and transition toward recovery and survivorship.


What is your opinion of the benefits of vitamin D?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


What is your opinion of the benefits of zinc?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


Editorial: Do Our Sedation Practices Contribute to Increased Mortality in Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome?

From Critical Care Medicine. In this Editorial, the authors discuss the article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome” and suggest that reemploying the use of evidence-based strategies developed over the past 20 years through rigorous controlled trials is one of the best mechanisms by which to help critically ill adults with COVID-19 liberate from the ICU and transition toward recovery and survivorship. 


Using Nonheparin Anticoagulant to Treat a Near-Fatal Case With Multiple Venous Thrombotic Lesions During ChAdOx1 nCoV-19 Vaccination-Related Vaccine-Induced Immune Thrombotic Thrombocytopenia

From Critical Care Medicine. The authors describe the successful recovery from multiple and life-threatening venous thrombosis after ChAdOx1 nCoV-19 vaccination.


What doses of dexamethasone, antivirals, and immunomodulators do you recommend?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021


How would you address the recent literature about prolactin as an immunomodulator for COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021


Have any studies been done with immunoglobulin instead of prolactin?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021


Review of Approved Monoclonal Antibody Treatments for COVID-19

This resource details monoclonal antibody treatments that can be used to treat COVID-19.
This is SCCM curated COVID-19 microlearning content.


Sedation Practices

Focus on ABC elements of the ICU Liberation Bundle, specifically, 1) depth of sedation, 2) choosing the right agent, 3) daily interruption of sedation. This is SCCM curated COVID-19 microlearning content.

Curriculum Topic: ICU Liberation Bundle Implementation & Challenges


Treatments of Moderate and Severe COVID-19 Pneumonia

Antiviral and Immunomodulatory Therapies for COVID-19. This is SCCM curated COVID-19 microlearning content.

Curriculum Topic: Infectious Complications & Management of COVID-19 Infection / Nosocomial


Plasma Exchange in Patients With Severe Coronavirus Disease 2019: A Single-Center Experience

From Critical Care Explorations. The data in this study provide further evidence for plasma exchange as a novel therapeutic strategy in a subset of critically ill coronavirus disease 2019 patients by potentially reversing the complex coronavirus disease 2019 immunopathology.


What are the current recommended treatments for critically ill patients with COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 8, 2021


Can you comment on any current literature on the use of IV vitamin C, as well as ivermectin?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 8, 2021