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From Critical Care Medicine. In this single center study, the authors found that plasma exchange mitigates cytokine storm, reverses organ failure, and could improve survival in critically ill patients with coronavirus disease 2019 infection.
Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.
From Critical Care Explorations In this study, the authors round that thromboelastography with platelet mapping better characterizes the spectrum of coronavirus disease 2019 coagulation-related abnormalities and may guide more tailored, patient-specific therapies in thostudyse infected with coronavirus disease 2019.
From Critical Care Explorations. In this retrospective study, the authors sought to understand the association of preinfection daily oral anticoagulation use and the short-term mortality of patients hospitalized with coronavirus disease 2019.
From Critical Care Medicine. The authors believe that the findings of this study provide a rationale to consider plasma exchange as a therapeutic option in COVID-19 and to include von Willebrand factor and ADAMTS13 in the diagnostic workup.
From Critical Care Medicine. In a large multicenter cohort study of critically ill patients with coronavirus disease 2019, the authors found higher D-dimer levels were independently associated with a greater risk of death.
From Critical Care Explorations In this study, the authors sought to determine similarities and differences in clinical characteristics between the patients from two waves of severe acute respiratory syndrome coronavirus-2 infection at the time of hospital admission, as well as to identify risk biomarkers of coronavirus disease 2019 severity.
From Critical Care Explorations. The authors’ data, discussed in this article, did not support the use of thromboelastography to risk stratify critically ill adults with coronavirus disease 2019 for the development of venous thromboembolism or to guide decisions about anticoagulation.
From Critical Care Medicine. The authors describe and compare rates of venous thromboembolism and hemorrhage in patients with coronavirus disease 2019 against a historic population of patients with influenza pneumonia who required extracorporeal membrane oxygenation.
From Critical Care Medicine. This Online Letter to the Editor was written in response to an article by Mirsadraee et al. entitled “Prevalence of Thrombotic Complications in ICUTreated Patients With Coronavirus Disease 2019 Detected With Systematic CT Scanning.”
From Critical Care Explorations. In this Narrative Review, the authors conclude that clinicians should be prepared for the early identification of patients with suspicious symptoms and prompt treatment should be initiated to avoid catastrophic deterioration. They note that major societal guidelines provide useful recommendations for the diagnosis and management of patients with vaccine-induced immune thrombotic thrombocytopenia.
From Critical Care Explorations. In this Brief Report the authors examined whether interleukin-6 in critical coronavirus disease 2019 is higher in arterial than in central venous blood, as a sign of predominantly local pulmonal rather than systemic interleukin-6 production.
Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered.
From Critical Care Medicine. The authors sought to determine the frequency of venous thromboembolism in critically ill coronavirus disease 2019 patients and associate a degree of inflammatory marker elevation to venous thromboembolism development. They found that routine chemical venous thromboembolism prophylaxis may be inadequate in preventing venous thromboembolism in severe coronavirus disease 2019.
From Critical Care Medicine. Recent studies have reported a high incidence of thrombotic events in COVID-19. However, the significance of thromboembolic complications has not been widely appreciated. The purpose of this review is to provide current knowledge of this serious problem.
This study describes a simple and safe protocol of anticoagulation with low molecular weight heparin (LMWH) in combination with bedside sustained low efficiency hemodialysis (SLED) in COVID-19 patients.
In this question and answer webcast, attendees had the opportunity to post questions about managing critically ill patients with COVID-19 and other issues. Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were also addressed. Webcast held on June 19, 2020
From Critical Care Medicine. This Letter to the Editor is in response to the article "Coagulopathy of Coronavirus 2019" by Iba et a.