Todd Fraser, MD, speaks with Allan Garland, MD, about the article, “Interaction Between Fluids and Vasoactive Agents on Mortality in Septic Shock: A Multicenter, Observational Study,” published in Critical Care Medicine. Dr. Garland is the co-head of the Section of Critical Care Medicine at the University of Manitoba in Winnipeg, Canada. In this article, Dr. Garland and coauthors examine best practices in administering fluids and vasoactive agents, both common treatments of septic shock, and how these treatments interact.