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Margaret Parker, MD, FCCM, speaks with Victoria L. Pemberton, RN, MS, about her article published in the January Pediatric Critical Care Medicine titled, "Therapeutic Hypothermia After Pediatric Cardiac Arrest Trials: The Vanguard Phase Experience and Implications for Other Trials." The use of an 18-month vanguard phase in the Therapeutic Hypothermia After Cardiac Arrest Trials was beneficial to both investigators and the funding agency, allowing time to refine the protocol for feasibility and safety as well as time to complete administrative activities. Pemberton is a clinical trials specialist at The National Heart, Lung, and Blood Institute in Bethesda, Maryland.
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