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Use of Procalcitonin (PCT) for the diagnosis of infection has been studied extensively with conflicting results, in part because of the many different populations and clinical syndromes studied. This variability prompted Steven Reynolds, MD, FRCPC, and colleagues to report PCT values relative to baseline patient characteristics, ICU length of stay, infectious status and infecting organism. Jeffrey Guy, MD, delves into the conclusions of this article, “Longitudinal changes in procalcitonin in a heterogeneous group of critically ill patients,” with specific focus on why PCT is important when managing patients with suspected sepsis. Reynolds is a clinical assistant professor in the Department of Medicine at the University of British Columbia in Vancouver, British Columbia, Canada. Published: Crit Care Med. 2012 Oct;40(10):2781-7
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