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From Critical Care Explorations. In this paper, the authors report that three-dimensional printed ventilators, such as "CRISIS," propose a potential solution to increase the available number of vents for the United States and abroad, one that is dynamic and able to absorb the massive influx of hospitalized patients for the foreseeable future.
From Critical Care Explorations. In this study, the authors gathered available published resources including physicochemical and pharmacokinetic properties and suggest antiviral drug dosing adaptation for coronavirus disease 2019–infected critically ill patients receiving extracorporeal therapy.
From Critical Care Explorations. In this case report, the authors report a series of four critically ill pediatric patients with acute respiratory failure who received coronavirus disease 2019 convalescent plasma as a treatment strategy for severe disease.
From Critical Care Explorations. In this observational study, the authors concluded that extracorporeal membrane oxygenation retrieval can rescue young, previously healthy patients with severe coronavirus disease 2019 in whom all the conventional respiratory measures have failed and found that thrombotic and hemorrhagic complications are frequent in this cohort.
From Critical Care Explorations. In this study, the authors found that angiotensin-II treatment for coronavirus disease 2019–induced distributive shock was associated with rapid improvement in multiple physiologic indices and that angiotensin-II in coronavirus disease 2019–induced shock warrants further study.
From Critical Care Medicine. The authors measured temporal trends in survival over time in people with severe coronavirus disease 2019 requiring critical care (high dependency unit or ICU) management, and assessed whether temporal variation in mortality was explained by changes in patient demographics and comorbidity burden over time.
From Critical Care Explorations. In this Letter to the Editor, the authors report their findings from an observational study aimed to compare the difference in outcomes of critically ill patients with coronavirus disease 2019 who were intubated early versus later in the disease course.
From Critical Care Explorations. In this case report, the authors note that late extracorporeal membrane oxygenation may be considered in selected patients as a bridge to recovery. Further prospective studies are, however, needed.
From Pediatric Critical Care Medicine. In this report, the authors describe the hybrid model implemented at institutions in New York and London and discuss shared experiences, pitfalls, challenges, and adjustments required in caring for both young and older patients.
From Critical Care Explorations The authors examined whether increasing time between admission and intubation was associated with mortality in patients with coronavirus disease 2019 who underwent mechanical ventilation.
From Critical Care Explorations In this article, the authors observed and interpreted CT perfusion patterns of COVID-19 pulmonary features.
From Critical Care Explorations The authors characterize outcomes associated with high-flow nasal oxygen use in critically ill adult patients with coronavirus disease 2019-associated acute hypoxemic respiratory failure.
From Critical Care Explorations The authors discuss optimizing continuous renal replacement therapy circuit survival in coronavirus disease 2019 patients admitted to the ICU.
From Critical Care Explorations The authors describe how clinical pharmacists fulfilled an essential service during the coronavirus pandemic by working to ensure the best possible outcomes for the patients they served on the frontline.
From Critical Care Explorations In this study, the authors found that the Portsmouth Ventilator was able to perform well across all simulated pathologies and in vivo.
From Critical Care Explorations The authors share data and recommendations from a multidisciplinary team to highlight our institution’s clinical experiences and guidelines for managing cardiovascular complications of coronavirus disease 2019.
From Critical Care Explorations The authors conducted a multicenter cohort study to determine the effect of drug therapies on survival in mechanically ventilated patients with coronavirus disease 2019.
From Critical Care Medicine The authors describe how a PICU and a PICU care team were incorporated into a hospital-wide ICU care model during the coronavirus disease 2019 pandemic.
From Critical Care Medicine The authors invesitated the safety and efficacy of megadose sodium ascorbate in sepsis.
From Critical Care Medicine The authors tested and found that a previously defined bacterial sepsis endotype classifier recapitulates the same clinical and immunological endotypes in viral sepsis (coronavirus disease 2019).