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Healthcare workload has emerged as an important metric associated with poor outcomes. To measure workload, studies have used bed occupancy as a surrogate. However, few studies have examined frontline clinician workload and outcomes. Host Elizabeth Mack, MD, MS, FCCM, is joined by Michael Fundora, MD, FAAP, to discuss if the hypothesized frontline clinician workload, measured by bed occupancy and staffing, is associated with poor outcomes and unnecessary testing (Fundora M.P., et al. Pedtr Crit Care Med. 2021 August; 22:683-691). Michael Fundora is a physician in the Division of Cardiology, Department of Pediatrics, Children’s Healthcare of Atlanta at Emory University School of Medicine in Atlanta, Georgia. This podcast is sponsored by Mölnlycke.
In funding a five-year prospective multicenter study to determine the safest and most effective approach to sepsis intervention, the National Heart, Lung, and Blood Institute (NHLBI) is recognizing the significant accomplishments of the Surviving Sepsis Campaign (SSC) and the Society of Critical Care Medicine (SCCM) to improve outcomes in patients with sepsis.
Determine the safest, most effective approach to sepsis intervention.
SCCM is supporting transformative and informative research, encouraging thought and action through its grants, programs, sections, collaborative audits, and research networks.
From Critical Care Explorations. In this article, the authors share their experience with a patient with severe COVID-19 who was admitted to a clinical trial of an investigational COVID-19 therapeutic using video-telecommunication to obtain informed consent.
From Critical Care Medicine. The author set out to generate a consensus-based, prioritized list of outcomes for coronavirus disease 2019 trials.
From Critical Care Medicine. The authors aimed to establish a core outcomes set for trials in people with suspected or confirmed coronavirus disease 2019.
From Critical Care Medicine. In this article, the authors describe the importance of critical care clinical research that is not pandemic-focused during pandemic times; outline principles to assist in the prioritization of nonpandemic research during pandemic times; and propose a guiding framework for decisions about whether, when and how to continue nonpandemic research while still honoring the moral and scientific imperative to launch research that is pandemic-focused.
From Critical Care Medicine The authors identified patient characteristics that predict an increased likelihood of death within 30 days of the start of critical care for patients with coronavirus disease 2019, which included age, ethnicity, deprivation, body mass index, and prior dependency, among other characteristics.
From Critical Care Medicine In this letter, the authors discuss APACHE II scores being used to predict mortality in coronavirus disease 2019 patients, however it may not be replicable.
From Critical Care Explorations The authors piloted a randomized trial of IV immunoglobulin in coronavirus disease 2019 patients and found significantly improved hypoxia and reduced hospital length of stay.
From Critical Care Medicine The authors aim to provide hands-on statistical guidelines for harmonizing heterogeneous endpoints in coronavirus disease 2019 clinical trials.
From Critical Care Medicine. In this article, the authors identify research priorities that represent a roadmap for investigation in COVID-19.
From Critical Care Explorations. In this Letter to the Editor, the authors respond to an article by Dupuis et al., congratulating the contribution to the problem of identifying which patients with hypoxemic respiratory failure truly benefit from invasive ventilation and suggesting future studies of invasive ventilation consider using the target trial concept in order to minimize bias and maximize the clinical applicability of results.
From Critical Care Medicine. In this Review Article the authors performed a systematic literature review to identify rates of barotrauma, pneumothorax, and pneumomediastinum in coronavirus disease 2019 acute respiratory distress syndrome patients receiving invasive mechanical ventilation.
From Critical Care Explorations While the overall safety profile of the BNT162b2 coronavirus disease 2019 vaccine remains excellent for the general population, rare serious events have been reported. In this case report, the authors describe a case of multisystem inflammation and organ dysfunction of unknown mechanism beginning shortly after administration of the first dose of BNT162b2 coronavirus disease 2019 vaccine in a previously healthy recipient.
From Critical Care Medicine The authors determined the association between temperature trajectories and distinct manifestations of coronavirus disease 2019.
From Critical Care Explorations The authors investigate microvascular function in patients with critical coronavirus disease 2019.
Paul E. Wischmeyer, MD, EDIC, FASPEN, FCCM, has a highly personal understanding of the challenges of recovering from an intensive care unit (ICU) stay. Diagnosed at age 15 with ulcerative colitis, his colon was removed when it perforated and caused septic peritonitis. Throughout his life, he has had 27 major surgeries and multiple ICU stays for bowel resections after bowel obstructions or to address complications from recurrent intestinal obstructions. These experiences have motivated his research to test a personalized, remotely monitored, coached exercise program to help patients recover after ICU discharge.
The power of scientific collaboration has a broad reach. During the COVID-19 pandemic, more than 7000 clinical trials were registered, with more than 100 different countries represented. Samantha Gambles Farr, MSN, NP-C, CCRN, RNFA, was joined by SCCM Lifetime Achievement Award Recipient John C. Marshall, MD, FRCSC, FACS, at the 2023 Critical Care Congress to discuss the importance of research and scientific collaboration. Dr. Marshall has been involved in research programs with researchers around the globe and is a well-known speaker with nearly 600 published manuscripts. This podcast is sponsored by Dompé Pharmaceutical.