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Category: Pharmacology

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SCCM Pod-334 Vasopressors: Future Research

Margaret Parker, MD, MCCM, speaks with Lakhmir S. Chawla, MD, about future research related to the Congress session “Bench-Pressing in the ICU: Which Vasopressor Agent Should I Choose for My Patient?” which he presented at the 45th Critical Care Congress in Orlando, Florida. Dr. Chawla is an Intensivist and Nephrologist and is Professor of Anesthesiology and Critical Care Medicine at George Washington University in Washington, D.C.


SCCM Pod-332 Dexmedetomidine Use in Critically-Ill Children with Acute Respiratory Failure

Margaret Parker, MD, MCCM, speaks with Mary Jo C. Grant, APRN, PhD, about the article, “Dexmedetomidine Use in Critically-Ill Children with Acute Respiratory Failure,” published in the December 2016 issue of Pediatric Critical Care Medicine. Dr. Grant is a Pediatric Critical Care Nurse Practitioner in the Department of Pediatric Critical Care at Primary Children’s Hospital in Salt Lake City, Utah. In this article, Dr. Grant and coauthors complete a secondary analysis of data from the RESTORE clinical trial to describe dexmedetomidine (DEX) use in children supported on mechanical ventilation for acute respiratory failure. Pediatr Crit Care Med. 2016; 17(12):1131-1141.


SCCM Pod-316 The SPLIT Randomized Clinical Trial

Todd Fraser, MD, speaks with Paul Young, FCICM, about the article, “Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial,” published in The Journal of the American Medical Association. Dr. Young is an intensivist at Wellington Regional Hospital, and Programme Director of Intensive Care at the Medical Research Institute of New Zealand in Wellington, New Zealand. In this article, Dr. Young and coauthors examine the effect of a buffered crystalloid compared with saline on renal complications on patients admitted to the ICU.


SCCM Pod-315 Pharmacological Therapies for Intracranial Hypertension in Children With Severe TBI

Margaret Parker, MD, MCCM, speaks with Steven L. Shein, MD, about the article, “Effectiveness of Pharmacological Therapies for Intracranial Hypertension in Children With Severe Traumatic Brain Injury—Results From an Automated Data Collection System Time-Synched to Drug Administration,” published in the March 2016 issue of Pediatric Critical Care Medicine. Dr. Shein is an Assistant Professor of Pediatric Critical Care Medicine at Rainbow Babies & Children’s Hospital in Cleveland, Ohio. In this article, Dr. Shein and coauthors discuss effects of medications commonly used to treat intracranial hypertension in children with traumatic brain injury.


SCCM Pod-309 Overall Hypothermia Update

Margaret Parker, MD, MCCM, speaks with Benjamin Abella, MD, about his upcoming talk, “Overall Hypothermia Update,“ which he will present at the 45th Critical Care Congress as part of the Society’s Current Concepts in Adult Critical Care Pre-Course. Dr. Abella is Associate Professor of Emergency Medicine and Vice Chair of Research in the Department of Emergency Medicine at the University of Pennsylvania in Philadelphia, Pennsylvania. Dr. Abella discusses current hypothermia guidelines, the use of hypothermia as a treatment following cardiac arrest, and the benefits and challenges of implementing targeted temperature management protocols.


SCCM Pod-281 A Survey on the Sequence of Medications for Treatment of Hyperkalemia in the PICU

Margaret Parker, MD, MCCM, speaks with Nnenna O. Chime, MD, MPH, about the article, “A Survey Demonstrating Lack of Consensus on the Sequence of Medications for Treatment of Hyperkalemia among Pediatric Critical Care Providers,” published in the June 2015 issue of Pediatric Critical Care Medicine. Dr. Chime is a second-year resident in the Department of Pediatrics at the Albert Einstein College of Medicine and Children’s Hospital at Montefiore in New York. In this article, Dr. Chime and coauthors discuss the results of a scenario-based survey and the extent to which opinions diverge among pediatricians on the treatment of hyperkalemia.


SCCM Pod-259 NEJM Study Examines if Simvastatin Improves ARDS Outcomes

Todd Fraser, MD, speaks with Daniel F. McAuley, MD, about his article, “Simvastatin in the Acute Respiratory Distress Syndrome,” published in the October 2014 New England Journal of Medicine. McAuley and the Irish Critical Care Trials Group tested the hypothesis that treatment with simvastatin would improve clinical outcomes in patients with acute respiratory distress syndrome (ARDS). Studies in animals and in vitro and phase 2 studies in humans suggest that statins may be beneficial in the treatment of this condition.


SCCM Pod-197 CCM: Sedative Doses, Mechanical Ventilation and Delirium

Michael Weinstein, MD, FACS, FCCP, speaks with Christopher W. Seymour, MD, MSc, lead author on an article published in the October Critical Care Medicine, “Diurnal Sedative Changes During Intensive Care: Impact on Liberation from Mechanical Ventilation and Delirium.” Seymour is an assistant professor of critical care and emergency medicine at the University of Pittsburgh School of Medicine in Pittsburgh, Pennsylvania. He also is a core faculty member in the Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center in the Department of Critical Care, where he contributes to the Program on Critical Care Health Policy. Additionally, he was the Society’s 2012 Vision Grant recipient.


SCCM Pod-148 Adjunctive Corticosteroid Therapy in Pediatric Sepsis

Jerry J. Zimmerman, MD, PhD, FCCM, discusses his article published in the January Pediatric Critical Care Medicine, titled “Adjunctive Corticosteroid Therapy in Pediatric Severe Sepsis: Observations From the RESOLVE.” Zimmerman is a professor of pediatrics, chief of the Division of Critical Care Medicine and director of Continuous Quality Improvement at Seattle Children’s Hospital in Washington.


SCCM Pod-143 PCCM: The Effects of Heparin in Infants After Catheter-Related Thrombosis

Alan R. Schroeder, MD, discusses his article, “A Continuous Heparin Infusion Does Not Prevent Catheter-Related Thrombosis in Infants After Cardiac Surgery," published in the July Pediatric Critical Care Medicine. Schroeder is the chief of pediatric inpatient services at Santa Clara Valley Medical Center in San Jose, California. 


SCCM Pod-133 CCM: Human Factors to Medication and Patient Safety in the ICU

Matthew C. Scanlon, MD, discuses is article, “Value of Human Factors to Medication and Patient Safety in the Intensive Care Unit,” published as part of a supplement to the June 2010 issue of Critical Care Medicine. He discusses how human factors provide a framework for understanding safety failures in critical care settings. Scanlon is an associate professor for the Medical College of Wisconsin in Milwaukee and a physician at the Children’s Hospital of Wisconsin, specializing in pediatrics and pediatric critical care.


SCCM Pod-131 CCM: Dexmedetomidine vs. Midazolam: A Cost Minimization Analysis

Joseph F. Dasta, MSc, FCCM, discusses his article published in the February 2010 issue of Critical Care Medicine, titled “A Cost Minimization Analysis of Dexmedetomidine Compared with Midazolam for Long-Term Sedation in the Intensive Care Unit.” His study compared the costs and determined factors influencing these costs, finding that continuous sedation with dexmedetomidine results in significantly lower costs, primarily due to decreased length of stay and reduced ventilator days. Dasta is an adjunct professor at the University of Texas College of Pharmacy and professor emeritus at The Ohio State University. He serves as a member of SCCM Council and has been an integral leader within the Clinical Pharmacy and Pharmacology Section. In 2010, he was awarded with the American College of Critical Care Medicine’s Distinguished Investigator Award.


SCCM Pod-69 2007 Congress Special: Epinephrine Versus Norepinephrine for Septic Shock

Djillali Annane, MD, discusses a study on epinephrine versus norepinephrine for septic shock he presented during the 36th Critical Care Congress. Dr. Annane is professor of critical care Raymond Poincare Hospital in Garches, France. 


SCCM Pod-66 2007 Congress Special: Furosemide and Albumin in ARDS

Gregory Martin, MD, discusses some of the topics from his presentation during the 36th Critical Care Congress, "Furosemide and Albumin in ARDS." Dr. Martin is assistant professor of medicine at Emory University in Atlanta, Georgia, and the section head of pulmonary and critical care division at Grady Memorial Hospital where he is also the director of the medical and coronary ICUs. 


SCCM Pod-58 CC: Cardiology Pharmacotherapies

Frederick P. Ognibene, MD, FCCM, discusses his goals as the Society's president for 2007 as well as his decades-long involvement in SCCM and the critical care community. Dr. Ognibene is director of the office of clinical research training and medical education at the National Institutes of Health (NIH) Clinical Center and the director of clinical research training program, OIR. He also is an attending in the medical intensive care unit at the NIH Clinical Center. 


SCCM Pod-57 CCM: Heparin-Induced Thrombocytopenia

Stanley Nasraway, MD, FCCM, discusses an article in the December issue of Critical Care Medicine "Heparin-induced thrombocytopenia in the critical care setting: Diagnosis and management." 


SCCM Pod-40 CCM: Initial Antimicrobial Treatment of MRSA

Marin Kollef, MD, professor of medicine in the department of pulmonary and critical care medicine at the Washington University School of Medicine and director of medical critical care at Barnes-Jewish Hospital, discusses his article in the August issue of Critical Care Medicine, "Methicillin-Resistant Staphylococcus aureus Sterile-Site Infection: The Importance of Appropriate Initial Antimicrobial Treatment."


Dexmedetomidine-Associated Hyperpyrexia in Three Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations. In this study of three patients, the authors state that their findings suggest that high doses of dexmedetomidine infusion are associated with hyperpyrexia in a seemingly dose-dependent fashion in critically ill patients with coronavirus disease 2019.
 


Can antiplatelets be administered at the same time as anticoagulation in patients with COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


Can children be anticoagulated or only adults?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021