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Renal Replacement Therapy for COVID-19 Patients

This resource details an the usage of renal replacement therapy for COVID-19 patients.

This is SCCM curated COVID-19 microlearning content.


Extracorporeal Blood Purification for COVID-19 and Beyond

This resource details an the usage of extracorporeal blood purification for COVID-19.

This is SCCM curated COVID-19 microlearning content.


Awake Proning with High Flow Nasal Cannula in COVID-19 ARDS

This resource details an the usage of awake proning with high flow nasal cannula in COVID ARDS.
This is SCCM curated COVID-19 microlearning content.


Epidemiological and Clinical Characterization of Superinfections in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Explorations. Prevalence of superinfections in coronavirus disease 2019 patients requiring mechanical ventilation was high in this series, and bacterial superinfections were independently associated with ICU or 28-day mortality (whichever comes first).


Examination of Early CNS Symptoms and Severe Coronavirus Disease 2019: A Multicenter Observational Case Series

From Critical Care Explorations. In this observational study, the authors found that early CNS symptoms, and pecifically encephalopathy, are differentially associated with risk of severe coronavirus disease 2019 and may serve as an early marker for differences in clinical disease course.


Scarce Resource Allocation in a Pandemic: A Protocol to Promote Equity, Timeliness, and Transparency

From Critical Care Explorations. Drawing on expertise in critical care medicine, bioethics, and political science, the authors propose a decision-making protocol to ensure fairness in the resolution of conflict, timely decision-making, and accountability to improve system response.


Using Nonheparin Anticoagulant to Treat a Near-Fatal Case With Multiple Venous Thrombotic Lesions During ChAdOx1 nCoV-19 Vaccination-Related Vaccine-Induced Immune Thrombotic Thrombocytopenia

From Critical Care Medicine. The authors describe the successful recovery from multiple and life-threatening venous thrombosis after ChAdOx1 nCoV-19 vaccination.


Endothelial Dysfunction as a Component of Severe Acute Respiratory Syndrome Coronavirus 2–Related Multisystem Inflammatory Syndrome in Children With Shock

From Critical Care Medicine. In this article, the authors found that endothelial dysfunction is associated with severe acute respiratory syndrome coronavirus 2–related multisystem inflammatory syndrome in children with shock and may constitute one of the underlying mechanisms.


Return to Work After Coronavirus Disease 2019 Acute Respiratory Distress Syndrome and Intensive Care Admission: Prospective, Case Series at 6 Months From Hospital Discharge

From Critical Care Medicine. In this Online Brief Report, the authors describe rates of return to work versus unemployment following coronavirus disease 2019 acute respiratory distress syndrome requiring intensive care admission.


Awake Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019 Patients Without Invasive Mechanical Ventilation

From Critical Care Explorations. This is a case report on the use of awake extracorporeal membrane oxygenation as a “treatment” for barotrauma due to severe acute respiratory distress syndrome in a coronavirus disease 2019 patient, without the need for invasive mechanical ventilation.


Development and Validation of ARC, a Model for Anticipating Acute Respiratory Failure in Coronavirus Disease 2019 Patients

From Critical Care Explorations. In this predictive modeling report, the authors sought to evaluate factors predictive of clinical progression among coronavirus disease 2019 patients following admission, and whether continuous, automated assessments of patient status may contribute to optimal monitoring and management.


Online Letter to the Editor: Optimal Management of Thrombotic Complications in Patients With Coronavirus Disease 2019

From Critical Care Medicine. This Online Letter to the Editor was written in response to an article by Mirsadraee et al. entitled “Prevalence of Thrombotic Complications in ICUTreated Patients With Coronavirus Disease 2019 Detected With Systematic CT Scanning.”


Online Letter to the Editor: Reasons for the Overuse of Sedatives and Deep Sedation for Mechanically Ventilated Coronavirus Disease 2019 Patients

From Critical Care Medicine. This Online Letter to the Editor was written in response to an article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019-Related Acute Respiratory Distress Syndrome: A Retrospective Cohort Study.”


Online Letter to the Editor: The Janus Face of Coronavirus Disease 2019–Associated Coagulopathy

From Critical Care Medicine. This Online Letter to the Editor is in response to an article by Doyle et al. entitled “A comparison of thrombosis and hemorrhage rates in patients with severe respiratory failure due to coronavirus disease 2019 and influenza requiring extracorporeal membrane oxygenation.”


Online Letter to Editor: Optimal Patient Selection for the Prophylactic Anticoagulation Therapy in Patients With Coronavirus Disease 2019

From Critical Care Medicine. This Online Letter to the Editor was written in response to an article by Santoro et al. entitled “Anticoagulation Therapy in Patients With Coronavirus Disease 2019: Results From a Multicenter International Prospective Registry (Health Outcome Predictive Evaluation for Corona Virus Disease 2019 [HOPE-COVID19]).”


Editorial: Glucocorticoid-Glucocorticoid Receptor Response to Severe Acute Respiratory Syndrome Coronavirus 2

From Critical Care Medicine. This Editorial accompanies an article by Vassiliou et al. entitled “Increased Glucocorticoid Receptor Alpha Expression and Signaling in Critically Ill Coronavirus Disease 2019 Patients.”


Editorial: The Long Road to Normalcy Following Survival From COVID-19–Associated Acute Respiratory Distress Syndrome

From Critical Care Medicine. This editorial accompanies an article by Carenzo et al. entitled “Return to Work After Coronavirus Disease 2019 Acute Respiratory Distress Syndrome and Intensive Care Admission: Propsective, Case-Series at 6 Months From Hospital Discharge” and calls for future studies to identify evidence for best practice during treatment of acute phase of infection to mitigate some of the long lasting effects as well as factors to help maximize rehabilitation efforts to help survivors to return to their everyday lives.


Editorial: Coronavirus Disease 2019: There Is a Heart Between the Lungs

From Critical Care Medicine. This Editorial was written in response to the article by Chotalia et al. “Right Ventricular Dysfunction and Its Association With Mortality in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome.”


Editorial: Utility of Coronavirus Disease 2019 Immune Profiling for the Clinician at the Bedside

From Critical Care Medicine. This Editorial was written in response to the article by de Roquetaillade et al. entitled “Comparison of Circulating Immune Cells Profiles and Kinetic Between Coronavirus Disease 2019 and Bacterial Sepsis,” which explores the relationship between the immune profile of COVID-19 patients and clinical outcomes.


Coronavirus Disease 2019: A Pandemic Spawning an Infodemic

From Pediatric Critical Care Medicine. In this Special Article, the authors make a call for the field of pediatric critical care to “move forward.” They note that, over a short period, some of the best science and resources have been applied to children with COVID-19 or MIS-C, and that now clinicians and scientists have a different objective: to translate what they learn and know into the highest level of care for patients.


Increased Glucocorticoid Receptor Alpha Expression and Signaling in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Medicine. In this study, the authors found that ICU coronavirus disease 2019 patients showed upregulated glucocorticoid receptor alpha and glucocorticoid-inducible leucine zipper expression, along with cortisol levels, compared with ICU noncoronavirus disease 2019 patients. Thus, they concluded, on ICU admission, critical coronavirus disease 2019 appears to be associated with hypercortisolemia, and increased synthesis of glucocorticoid receptor alpha and induced proteins.


Editorial: Do Our Sedation Practices Contribute to Increased Mortality in Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome?

From Critical Care Medicine. In this Editorial, the authors discuss the article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome” and suggest that reemploying the use of evidence-based strategies developed over the past 20 years through rigorous controlled trials is one of the best mechanisms by which to help critically ill adults with COVID-19 liberate from the ICU and transition toward recovery and survivorship. 


Editorial: Advancing Telehealth-Based Screening for Postintensive Care Syndrome: A Coronavirus Disease 2019 Paradigm Shift

From Critical Care Medicine. In this Editorial, the authors discuss the article by Martillo et al. entitled “Postintensive Care Syndrome in Survivors of Critical Illness Related to Coronavirus Disease 2019: Cohort Study From a New York City Critical Care Recovery Clinic.” 


Online Letter to the Editor: Postcoronavirus Disease Chronic Fatigue Is Frequent and Not Only Restricted to Hospitalized Patients

From Critical Care Medicine. This Online Letter to the Editor was written in response to a paper by Martillo et al. entitled “Postintensive Care Syndrome in Survivors of Critical Illness Related to Coronavirus Disease 2019: Cohort Study From a New York City Critical Care Recovery Clinic,’ in which the authors reported a high-proportion of patients suffering from chronic fatigue 1 month after discharge from hospital for ICU-treated coronavirus disease 2019.


Ethical Considerations for a COVID-19 Vaccine Mandate

Mandate to vaccinate or nudge if there is no budge? COVID-19 vaccines remain a key weapon in the fight against the deadliest modern-day pandemic the world has seen. In this article, we summarize key facts and ethical considerations for healthcare organizations when considering a COVID-19 vaccine mandate for U.S. healthcare workers (HCW).


Concise Critical Appraisal: Cardiac Ultrasound in Pediatric Septic Shock Assessment

How can clinical information gleaned from focused cardiac ultrasound (FCU) be used to augment clinical assessments in children with suspected septic shock? This month’s Concise Critical Appraisal analyzes a study published in Pediatric Critical Care Medicine that sought to show how often a clinician’s hemodynamic characterization of a child with septic shock was altered by FCU and to further validate an expert-developed algorithm for these assessments.


Can you comment on the use of palliative care in patients with COVID-19 in the emergency department or ICU? When should we start reaching out to these colleagues?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


What is your opinion of the benefits of zinc?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


What is your opinion of the benefits of vitamin D?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


If a patient develops hypotension in the emergency department, how should this be addressed?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


What is the best approach to acute COVID-19 management in the emergency department?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


Should BiPAP be used in patients with COVID-19 or should it be avoided? If you decide to intubate a patient, which parameters should be used and what initial ventilatory settings do you recommend?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


Do patients with dementia have increased delirium? What is the best way to address this issue at admission to decrease patient suffering later?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


CDC Resources: Disaster

SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Centers for Disease Control and Prevention (CDC). These resources are categorized as Disaster


CDC Resources: Cardiovascular

SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Centers for Disease Control and Prevention (CDC). These resources are categorized as Cardiovascular


IDSA Resources: Quality and Patient Safety

SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Infectious Diseases Society of America (IDSA) COVID-19 Real-Time Learning Network. These resources are categorized as Quality and Patient Safety


IDSA Resources: Disaster

SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Infectious Diseases Society of America (IDSA) COVID-19 Real-Time Learning Network. These resources are categorized as Disaster


Can you expand on the use of anticoagulation in patients who have been diagnosed with COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


How should delirium be addressed in ICU patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


What processes should be established to update family members on the patient’s progress, especially if the patient is declining?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


What are basic principles of managing patients when they are transferred to the ICU setting?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


What is your opinion on management of patients’ health in the emergency department?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


A Review of Acute Respiratory Distress Syndrome and COVID-19

Is COVID-19 just atypical acute respiratory distress syndrome (ARDS)? Multidisciplinary faculty will discuss the research and varying answers to this question in this SCCM webcast. During this webcast faculty covered evidence-based best practices for airway management now that more is known about COVID-19. The Society of Critical Care Medicine and the American Association of Respiratory Care partnered to produce this webinar on COVID-19. Webcast Recorded on Wednesday, May 26, 2021


Coronavirus Disease 2019: A Pandemic Spawning an Infodemic

From Pediatric Critical Care Medicine. In this Special Article, the authors make a call for the field of pediatric critical care to “move forward.” They note that, over a short period, some of the best science and resources have been applied to children with COVID-19 or MIS-C, and that now clinicians and scientists have a different objective: to translate what they learn and know into the highest level of care for patients.


Editorial: Do Our Sedation Practices Contribute to Increased Mortality in Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome?

From Critical Care Medicine. In this Editorial, the authors discuss the article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome” and suggest that reemploying the use of evidence-based strategies developed over the past 20 years through rigorous controlled trials is one of the best mechanisms by which to help critically ill adults with COVID-19 liberate from the ICU and transition toward recovery and survivorship.


Editorial: Advancing Telehealth-Based Screening for Postintensive Care Syndrome: A Coronavirus Disease 2019 Paradigm Shift

From Critical Care Medicine. In this Editorial, the authors discuss the article by Martillo et al. entitled “Postintensive Care Syndrome in Survivors of Critical Illness Related to Coronavirus Disease 2019: Cohort Study From a New York City Critical Care Recovery Clinic.” The Editorial authors conclude that questions remain about when and how to screen for PICS and whether severe COVID-19 survivors have unique symptoms or trajectories compared with non-COVID-19 critical illness survivors, and they emphasize that the main public health message is clear -- critical illness, in general, and severe COVID-19, specifically, are life changing and the critical care community needs to do all it can to prevent the development of PICS and raise awareness.


Online Letter to the Editor: Postcoronavirus Disease Chronic Fatigue Is Frequent and Not Only Restricted to Hospitalized Patients

From Critical Care Medicine. This Online Letter to the Editor was written in response to a paper by Martillo et al. entitled Postintensive Care Syndrome in Survivors of Critical Illness Related to Coronavirus Disease 2019: Cohort Study From a New York City Critical Care Recovery Clinic,’ in which the authors reported a high-proportion of patients suffering from chronic fatigue 1 month after discharge from hospital for ICU-treated coronavirus disease 2019.


Increased Glucocorticoid Receptor Alpha Expression and Signaling in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Medicine. In this study, the authors found that ICU coronavirus disease 2019 patients showed upregulated glucocorticoid receptor alpha and glucocorticoid-inducible leucine zipper expression, along with cortisol levels, compared with ICU noncoronavirus disease 2019 patients. Thus, they concluded, on ICU admission, critical coronavirus disease 2019 appears to be associated with hypercortisolemia, and increased synthesis of glucocorticoid receptor alpha and induced proteins.


An SCCM Member Responds to a Call for Volunteers

Before the COVID-19 pandemic, Tina R. Shah, MD, MPH, focused her work on two questions: How can technology help improve the United States health system and, more specifically, how can it be used to improve patient and practitioner well-being?


Specialty Section

Join a Specialty Section to connect with SCCM members with similar interests and advance the specialties that matter most to you. 


CDC Resources: Hematology

SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Centers for Disease Control and Prevention (CDC). These resources are categorized as Hematology


Tocilizumab for the Treatment of Severe COVID-19 Pneumonia in Critically Ill Patients: Trendy or Tried-and-True?

This resource details an the usage of tocilizumab as a treatment for severe COVID-19.
This is SCCM curated COVID-19 microlearning content.


Is Microthrombosis the Main Pathology in Coronavirus Disease 2019 Severity?—A Systematic Review of the Postmortem Pathologic Findings

From Critical Care Explorations.  In this systematic review, the authors attempted to retrieve and report the findings of postmortem studies including the histopathologic data of deceased coronavirus disease 2019 patients and to review the manifestations of coronavirus disease 2019–associated thrombotic pathologies reported in the recent literature. Diffuse alveolar damage was the most predominant feature in the lungs of coronavirus disease 2019 patients who underwent postmortem assessment. Widespread pulmonary microthrombosis and extensive pulmonary angiogenesis, in addition to frequent pulmonary and extrapulmonary microthrombotic and thromboembolic findings in patients with coronavirus disease 2019, appear to be consistent with the disease-specific hypercoagulability.


Letter to the Editor: Less Lumping and More Splitting: Why We Should Not Call COVID Sepsis

From Critical Care Medicine. This Letter to the Editor is in response to an editorial by Shappell et al. entitled “Does Severe Acute Respiratory Syndrome Coronavirus 2 Cause Sepsis?”


Comparison of Circulating Immune Cells Profiles and Kinetics Between Coronavirus Disease 2019 and Bacterial Sepsis

From Critical Care Medicine.  In this article the authors present a longitudinal analysis of the immune response in coronavirus disease 2019 patients, its correlation with outcome, and comparison between severe coronavirus disease 2019 patients and septic patients. They conclude that severe coronavirus disease 2019 is associated with a unique immune profile as compared with sepsis. Several immune features are associated with outcome and suggest that immune monitoring of coronavirus disease 2019 might be helpful for patient management.


Outcome Improvement Between the First Two Waves of the Coronavirus Disease 2019 Pandemic in a Single Tertiary-Care Hospital in Belgium

From Critical Care Explorations.  In this article, the authors note that the main therapeutic changes between the first wave of the coronavirus disease 2019 pandemic and the second wave of the coronavirus disease 2019 pandemic were use of steroids, unrestrictive use of high-flow nasal oxygen for hypoxemic patients, and transfer of patients to other geographic areas in the case of ICU overcrowding. They found that these changes were associated with a decrease in 30-day mortality, ICU admission, and organ support.


A High Neutrophil-Lymphocyte Ratio Is Associated With Increased Morbidity and Mortality in Patients With Coronavirus Disease 2019

From Critical Care Explorations.  This study aimed to evaluate the prognostic potential of admission neutrophil-lymphocyte ratio in patients admitted to the medical ICU with coronavirus disease 2019. The authors concluded that the neutrophil-lymphocyte ratio at the time of hospital admission is an independent risk factor for morbidity and mortality. This prognostic indicator may assist clinicians appropriately identify patients at heightened risk for a severe disease course and tailor treatment accordingly.


A Multicenter Evaluation of Survival After In-Hospital Cardiac Arrest in Coronavirus Disease 2019 Patients

From Critical Care Explorations.  In-hospital cardiac arrest survival among coronavirus disease 2019 patients has been reported to range from 0% to 12% -- significantly lower than reported prepandemic in-hospital cardiac arrest survival rates of approximately 20% to 25% in the United States for non–coronavirus disease 2019 patients. In this multi-center study, the authors report a 22% survival to discharge after in-hospital cardiac arrest in coronavirus disease 2019 patients, a survival rate similar with before the coronavirus disease 2019 pandemic.


Letter to the Editor: Cytokine Blockade in Coronavirus Disease 2019: Keeping an Open Mind

From Critical Care Explorations.  This Letter to the Editor was written in response to the article by Rizvi and Gallo De Moraes entitled “New Decade, Old Debate: Blocking the Cytokine Pathways in Infection-Induced Cytokine Cascade.”


Timing of Intubation in Coronavirus Disease 2019: A Study of Ventilator Mechanics, Imaging, Findings, and Outcomes

From Critical Care Explorations  The authors sought to determine the variation in outcomes and respiratory mechanics between the subjects who are intubated earlier versus later in their coronavirus disease 2019 course.


Characteristics, Comorbidities, Complications, and Outcomes Among 802 Patients With Severe Acute Respiratory Syndrome Coronavirus 2 in a Community Hospital in Florida

From Critical Care Explorations.  In this study, the authors reviewed the demographics, characteristics, comorbidities, complications, and outcomes of hospitalized patients with severe acute respiratory syndrome coronavirus 2, and their association with mortality at medical center in Orlando, Florida.


Can you discuss post-COVID-19 care for patients who have had prolonged hospitalization?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


How have sepsis protocols or bundles been used in COVID-19 patients and what is the best way to navigate these bundles, especially regarding fluids?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


Do you suggest encouraging families to delegate a single spokesperson for the family to receive information?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


When should a bacterial superinfection be suspected in COVID-19 patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


What is the most appropriate practice for handling information about COVID-19 patients when talking with patients’ families?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


Now that patients are being vaccinated, when ruling out COVID-19 in patients who might have pneumonia or pulmonary embolism, how should their vaccination status be taken into account?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


Many intubated COVID-19 patients are requiring renal replacement therapy. How is acute renal failure prevented in these patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


When should furosemide be used in COVID-19 patients? Some COVID-19 patients are presenting with diarrhea rather than respiratory symptoms. Is there any evidence-based treatment for this?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


Can you discuss the use of anticoagulation for blood clot prevention in COVID-19 patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


Can you discuss sedation strategies for COVID-19 patients who are on mechanical ventilation or ECMO?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


For COVID-19 patients who are not candidates for mechanical ventilation, which of these patients are candidates for extracorporeal membrane oxygenation (ECMO)?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


Can you discuss ventilator management for the novice clinician and the optimal time for intubation in  COVID-19 patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


How is it determined whether early intubation is a good strategy for a patient?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


Which strategies have you found to be most useful in keeping patients off mechanical ventilation and out of the ICU?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


Post-COVID-19: Considerations From ICU to Discharge (Infographic)

This infographic covers pearls on how to mitigate post-COVID-19: from ICU to discharge. This is SCCM curated COVID-19 microlearning content.


Post-Acute Sequelae of COVID-19 (PASC): What Can Be Done in and after the ICU to Lower the Risk of "Long COVID"?

This webinar panel discussed ways to mitigate the risk of post-acute sequelae of COVID-19 (PASC) in hospitalized COVID-19 patients. The panelists and attendees participated in an interactive discussion format with case presentations, polling, and given access to a downloadable infographic to use as a resource tool. The Society of Critical Care Medicine and the American Association of Respiratory Care partnered to produce this webinar on COVID-19. Webcast Recorded on Thursday, April 29, 2021


Coronavirus Disease 2019–Associated PICU Admissions: A Report From the Society of Critical Care Medicine Discovery Network Viral Infection and Respiratory Illness Universal Study Registry

From Pediatric Critical Care Medicine. This study delineates significant clinically relevant differences in presentation, explanatory factors, and outcomes among children admitted to PICU with severe acute respiratory syndrome coronavirus 2–related illness stratified by multisystem inflammatory syndrome in children.


Functional Outcomes and Their Association With Physical Performance in Mechanically Ventilated Coronavirus Disease 2019 Survivors at 3 Months Following Hospital Discharge: A Cohort Study

From Critical Care Medicine. The authors found that physical disability is common at 3 months in severe coronavirus disease 2019 survivors. Lung diffusing capacity and intermuscular adipose tissue assessed on CT were independently associated with walking distance, suggesting a key role for pulmonary function and muscle quality in functional disability.


Prone Positioning of Nonintubated Patients With Coronavirus Disease 2019—A Systematic Review and Meta-Analysis

From Critical Care Medicine. In this systematic review and meta-analysis, the authors found that, despite the significant variability in frequency and duration of prone positioning and respiratory supports applied, prone positioning was associated with improvement in oxygenation variables without any reported serious adverse events.


Letter to the Editor: Bias Due to Cohort Construction in the Study of Timing of Invasive Ventilation

From Critical Care Explorations. In this Letter to the Editor, the authors respond to an article by Dupuis et al., congratulating the contribution to the problem of identifying which patients with hypoxemic respiratory failure truly benefit from invasive ventilation and suggesting future studies of invasive ventilation consider using the target trial concept in order to minimize bias and maximize the clinical applicability of results.


Determining Cause of Death During Coronavirus Disease 2019 Pandemic

From Critical Care Explorations. In this single-center study, the authors found that the majority of deaths in severe acute respiratory syndrome coronavirus 2–positive hospitalized patients were related to a typical or atypical presentation of coronavirus disease 2019 disease.


Frugal Innovation: Enabling Mechanical Ventilation During Coronavirus Disease 2019 Pandemic in Resource-Limited Settings

From Critical Care Explorations. In this commentary, the authors note that low-quality care has become a greater determinant of mortality than lack of access. To address this, they suggest a systems-wide approach to improving the quality of mechanical ventilation in resource-limited settings, which includes consideration of the interdependent ventilator design constraints such as cost and complexity, hospital infrastructure, availability of medications, and trained personnel.


Existing Crisis Standards of Care Triage Protocols May Not Significantly Differentiate Between Patients With Coronavirus Disease 2019 Who Require Intensive Care

From Critical Care Explorations. The authors sought to determine how several existing crisis standards of care triage protocols would have distinguished between patients with coronavirus disease 2019 requiring intensive care.


Health Care Worker Burnout (Infographic)

This infographic details health care worker burnout. This is SCCM curated COVID-19 microlearning content.


Pressure Injuries (Infographic)

This resource is an infographic detailing pressure injuries. This is SCCM curated COVID-19 microlearning content.


Post-Acute COVID-19 Syndrome

This resource details Post-Acute COVID-19 Syndrome (PASC). This is SCCM curated COVID-19 microlearning content.


Editorial: Convalescent Plasma and Coronavirus Disease 2019: Time for Reassessment

From Critical Care Medicine. In this Editorial, the wonder if the use of convalescent plasma needs to be further whittled to an even smaller subset of patients and ultimately whether there is even a practical role for this therapy in the treatment of COVID-19 particularly in hospitalized patients.


Online Letter to the Editor: Understanding the Underlying Mechanisms of Hyponatremia in Coronavirus Disease 2019 Is Critical Since Treatment Varies Based on Etiology: Let Us Not Forget Critical Illness-Related Corticosteroid Insufficiency As the Treatment

From Critical Care Medicine. In this Online Letter to the Editor, the authors write in response to an article by Frontera et al. in Critical Care Medicine about etiology of hyponatremia in coronavirus disease 2019 (COVID-19) patients.


Acute Cardiac Injury in Coronavirus Disease 2019 and Other Viral Infections—A Systematic Review and Meta-Analysis

From Critical Care Medicine. In this review article, the authors compared the rates of cardiac injury by angiotensin converting enzyme-2–binding viruses from viruses that do not bind to angiotensin-converting enzyme-2.


Severe Acute Respiratory Syndrome Coronavirus 2 Convalescent Plasma Versus Standard Plasma in Coronavirus Disease 2019 Infected Hospitalized Patients in New York: A Double-Blind Randomized Trial

From Critical Care Medicine. In this study, the authors found that administration of convalescent plasma to hospitalized patients with coronavirus disease 2019 infection increased antibodies to severe acute respiratory syndrome coronavirus disease 2 but was not associated with improved outcome.


Letter to the Editor: Outcomes and Safety of Early Percutaneous Tracheostomy in Coronavirus Disease 2019 Patients Admitted to the ICU

From Critical Care Medicine. This letter to the editor was written in response to "Early Percutaneous Tracheostomy in Coronavirus Disease 2019: Association With Hospital Mortality and Factors Associated With Removal of Tracheostomy Tube at ICU Discharge. A Cohort Study on 121 Patients."


Coronavirus Disease 2019 ICU Patients Have Higher-Than-Expected Acute Physiology and Chronic Health Evaluation–Adjusted Mortality and Length of Stay Than Viral Pneumonia ICU Patients

From Critical Care Medicine. The authors compared APACHE-IV–adjusted mortality and length of stay outcomes of adult ICU patients who tested positive for coronavirus disease 2019 with patients admitted to ICU with other viral pneumonias.


Coronavirus Disease 2019 Policy Restricting Family Presence May Have Delayed End-of-Life Decisions for Critically Ill Patients

From Critical Care Medicine. The authors investigate if a restrictive visitor policy inadvertently lengthened the decision making process for dying inpatients without coronavirus disease 2019.


Editorial: Capacity Strain and Response During Coronavirus Disease 2019: One Size Does Not Fit All, and One Size Does Not Fit One

From Critical Care Medicine. In this editorials, the authors discuss hospital preparedness in the article "Variation in Initial U.S. Hospital Responses to the Coronavirus Disease 2019 Pandemic."


Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome: A Retrospective Cohort Study

From Critical Care Medicine. The authors tested the hypothesis that patients with coronavirus disease 2019–associated acute respiratory distress syndrome are at higher risk of in-hospital mortality due to prolonged coma compared with other patients with acute respiratory distress syndrome matched for disease severity.


Surge and Mortality in ICUs in New York City’s Public Healthcare System

From Critical Care Medicine. The authors evaluate the impact of ICU surge on mortality and to explore clinical and sociodemographic predictors of mortality.


Update on Multisystem Inflammatory Syndrome in Children (MIS-C)

This resource details an update on MIS-C during the COVID-19 pandemic. This is SCCM curated COVID-19 microlearning content.


Concise Critical Appraisal: Development of the CCEeXAM

Bedside echocardiography has become increasingly widespread among physicians caring for critically ill patients. The Examination of Special Competence in Critical Care Echocardiography (CCEeXAM) was administered for the first time in 2019 to 524 physicians from multiple specialties. The examination was designed for physicians to demonstrate an objective competence and obtain certification in advanced critical care echocardiography (CCE).


Does your institution provide guidelines as to when a patient with COVID-19 needs intensive care? Do these parameters change based on hospital capacity?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


Which markers or patient features would cause you to choose noninvasive or high-flow nasal cannula over intubation for early management of COVID-19 respiratory failure?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


For patients with COVID-19 being treated with intermediate- or full-dose enoxaparin, have anti-Xa levels been checked? If so, have higher-than-expected anti-Xa levels been found?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


Should anticoagulation or antiplatelet therapy be used for patients with COVID-19? Should these patients be empirically anticoagulated? How is your institution handling this?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


At your institution, have you used procalcitonin as a trending marker to aid in the identification of pulmonary infection?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


For patients who have acute respiratory distress syndrome from COVID-19 and are on a ventilator, how do you identify secondary lung infections?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


Do you favor pressure or volume control ventilation in patients with acute respiratory distress syndrome from COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


Does ketamine help resolve agitation or delirium? Are hallucinations a possible side effect of ketamine?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


For patients with severe acute respiratory distress syndrome from COVID-19, how do you prevent delirium when you cannot provide a sedation vacation or spontaneous breathing trial?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


When delirium prevention measures are ineffective for ICU patients with delirium, which therapies do you recommend trying next?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


Which environmental and medical therapies do you believe are most effective in preventing delirium in the ICU?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


Variation in Initial U.S. Hospital Responses to the Coronavirus Disease 2019 Pandemic

From Critical Care Medicine. The authors characterize emergency responses across hospitals in the United States over time and in the context of local case rates early in the coronavirus disease 2019 pandemic.


Percutaneous Dilational Tracheostomy for Coronavirus Disease 2019 Patients Requiring Mechanical Ventilation

From Critical Care Medicine. The authors assess the impact of percutaneous dilational tracheostomy in coronavirus disease 2019 patients requiring mechanical ventilation and the risk for healthcare providers.


Anticoagulation Therapy in Patients With Coronavirus Disease 2019: Results From a Multicenter International Prospective Registry (Health Outcome Predictive Evaluation for Corona Virus Disease 2019 [HOPE-COVID19])

From Critical Care Medicine. The authors evaluate the efficacy of anticoagulation in coronavirus disease 2019 hospitalized patients and its impact on survival.


A Comparison of Thrombosis and Hemorrhage Rates in Patients With Severe Respiratory Failure Due to Coronavirus Disease 2019 and Influenza Requiring Extracorporeal Membrane Oxygenation

From Critical Care Medicine. The authors describe and compare rates of venous thromboembolism and hemorrhage in patients with coronavirus disease 2019 against a historic population of patients with influenza pneumonia who required extracorporeal membrane oxygenation.


The Characterization of the Toll of Caring for Coronavirus Disease 2019 on ICU Nursing Staff

From Critical Care Explorations. In this brief report, the authors conclude there are indications that registered nurses providing care for coronavirus disease 2019 in the ICU reported increased thermal discomfort coinciding with elevated energy expenditure and a more pronounced self-perception of effort, stress, and mental demand.


The Initial Impact of the Coronavirus Disease 2019 Pandemic on ICU Family Engagement: Lessons Learned From a Collaborative of 27 ICUs

From Critical Care Explorations. While the collaborative model can help promote ICU family engagement initiatives, the authors found that coronavirus disease 2019 has impeded implementation of these initiatives even among motivated units.


In Vitro–Administered Dexamethasone Suppresses T Cell Function With Reversal by Interleukin-7 in Coronavirus Disease 2019

From Critical Care Explorations. The authors evaluated the in vitro effects of dexamethasone phosphate on T cell function in peripheral blood mononuclear cells derived from patients with acute, severe, and moderate coronavirus disease 2019.


Editorial: Be Careful and Protect Yourself, It Is in the Air

From Critical Care Medicine. In this editorial, the authors discuss hospital staff safety in the article "Transmission of Severe Acute Respiratory Syndrome Coronavirus 1 and Severe Acute Respiratory Syndrome Coronavirus 2 During Aerosol-Generating Procedures in Critical Care: A Systematic Review and Meta-Analysis of Observational Studies" by Chan et al.


Letter to the Editor: Unclear Benefit of Early Tracheostomy In Patients With Coronavirus Disease 2019

From Critical Care Medicine. This online letter to the editor was written in response to Early Percutaneous Tracheostomy In Coronavirus Disease 2019: Association With Hospital Mortality and Factors Associated With Removal of Tracheostomy Tube at ICU Discharge. A Cohort Study on 121 Patients" by Rosano et al.


Letter to the Editor: Questioning the Futility of Cardiopulmonary Resuscitation in Patients With Severe Coronavirus Disease 2019

From Critical Care Medicine. This online letter to the editor was written in response to " Is Cardiopulmonary Resuscitation Futile in Coronavirus Disease 2019 Patients Experiencing In-Hospital Cardiac Arrest?" by Shah et al.


Letter to the Editor: Cardiopulmonary Resuscitation in Coronavirus Disease 2019: Far from Futile

From Critical Care Medicine. This online letter to the editor was written in response to " Is Cardiopulmonary Resuscitation Futile in Coronavirus Disease 2019 Patients Experiencing In-Hospital Cardiac Arrest?" by Shah et al.


Early Tocilizumab Dosing Is Associated With Improved Survival in Critically Ill Patients Infected With Severe Acute Respiratory Syndrome Coronavirus-2

From Critical Care Explorations. The authors identify the most efficacious timing for tocilizumab administration in critically ill patients infected with severe acute respiratory syndrome coronavirus-2.


Characteristics of Severe Acute Respiratory Syndrome Coronavirus-2 Infection and Comparison With Influenza in Children Admitted to U.K. PICUs

From Critical Care Explorations. The authors describe the nationwide U.K. PICU experience of severe acute respiratory syndrome coronavirus-2 infection during the first wave of the pandemic and compare this with the critical care course of the 2019 influenza cohort.


Mechanical Ventilation and Coronavirus Disease 2019: A Case-Control Analysis of Clinical Characteristics, Lung Mechanics, and Mortality

From Critical Care Explorations. The authors investigated the differences in clinical course, ventilator mechanics, and outcomes of patients with coronavirus disease 2019 secondary to acute respiratory distress syndrome infection compared with a historical cohort of acute respiratory distress syndrome.


Letter to the Editor: Comparing Seasonal Trends in Coronavirus Disease 2019 Patient Data at a Quaternary Hospital in New York City

From Critical Care Explorations. In this Letter to the Editor, the authors report initial patient characteristics and outcomes from a large quaternary referral center in New York City between Spring, Summer, and Winter, including prevalence of renal failure, respiratory failure, and mortality; stratified across several key populations of interest including all patients, ICU patients, those requiring of noninvasive positive pressure ventilation and high-flow nasal cannula, and those intubated in each time period.


Association Between Treatments and Short-Term Biochemical Improvements and Clinical Outcomes in Postsevere Acute Respiratory Syndrome Coronavirus-2 Inflammatory Syndrome

From Pediatric Critical Care Medicine. The authors analyzed the short-term biochemical improvements and clinical outcomes following treatment of children with postsevere acute respiratory syndrome coronavirus-2 inflammatory syndrome (multisystem inflammatory syndrome in children/pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus-2) admitted to U.K. PICUs and collated current treatment guidance from U.K. PICUs.


Johnson & Johnson’s Janssen COVID-19 Vaccine: What Clinicians Need to Know

In the past few weeks more than 7 million doses of Johnson & Johnson’s Janssen COVID-19 vaccine have been administered to people in the United States. In clinical trials of approximately 40,000 people, the J&J vaccine given as a single shot was 66% effective at preventing the illness due to the SARS-CoV-2 virus known as COVID-19. Because the J&J vaccine is a single shot, it has been preferred in some circumstances.


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Concise Critical Appraisal: Surviving Sepsis Campaign COVID-19 Guidelines Update

The updated Surviving Sepsis Campaign (SSC) COVID-19 guidelines are now available, reflecting the learnings from the latest major studies. This month’s Concise Critical Appraisal dives into the update to outline the changes and new recommendations made by the international panel and discusses limitations of the available data.


ICU Liberation: The Role of Rehabilitation Professionals

The ICU Liberation Bundle (A-F) can help rehabilitation practitioners and respiratory care practitioners (RCPs) assess the broad, long-term goals of patients while zooming in on the immediate steps needed to achieve short-term goals. Physical therapists (PTs), occupational therapists (OTs), speech language pathologists (SLPs), and RCPs all have a role in using the ICU Liberation Bundle when caring for patients in the intensive care unit (ICU).



Maternal Mortality During the COVID-19 Pandemic

This resource details maternal mortality during the COVID-19 pandemic.

This is SCCM curated COVID-19 microlearning content.


COVID-19 and Pregnancy, Management Considerations

This resource details COVID-19 and pregnancy management.

This is SCCM curated COVID-19 microlearning content.


Awake Self-Proning in COVID-19 ARDS

This resource details methods for awake self-proning for COVID-19 patients with ARDS. This is SCCM curated COVID-19 microlearning content.


Infection Control from the ED to the ICU: Triage to Transport

The care of patients with COVID-19 requires careful steps for preventing infection of staff and other patients throughout the continuum care from the emergency department to the ICU. This webinar consisted of an expert panel discussion of questions and case studies that addressed burning questions. Participants also received an infographic with pearls from the panel experts to help in their practice. Webcast Recorded on Friday, March 26, 2021


Infographic: Infection Control from the Emergency Department to the ICU

This infographic resource details best practices to mitigate infection control from the ED to the ICU.

This is SCCM curated COVID-19 microlearning content.


Online Letter to the Editor: Is “Mega-Dose” IV Vitamin C Required for Septic and Critical Coronavirus Disease 2019 Patients?

From Critical Care Medicine. This online letter to the editor was written in response to “Reversal of the Pathophysiological Responses to Gram-Negative Sepsis by Megadose Vitamin C” by Lankadeva et al


Online Letter to the Editor: Resuscitation and Coronavirus Disease 2019: A Reappraisal

From Critical Care Medicine. This online letter to the editor was written in response to the article “Is Cardiopulmonary Resuscitation Futile in Coronavirus Disease 2019 Patients Experiencing In-Hospital Cardiac Arrest? By Shah et al.


Online Letter to the Editor: Judging Futility of Resuscitation Attempts for Coronavirus Disease 2019 Patients Requires Better Time Data

From Critical Care Medicine. This online letter to the editor was written in response to the article “Is Cardiopulmonary Resuscitation Futile in Coronavirus Disease 2019 Patients Experiencing In-Hospital Cardiac Arrest? By Shah et al.


Postintensive Care Syndrome in Survivors of Critical Illness Related to Coronavirus Disease 2019: Cohort Study From a New York City Critical Care Recovery Clinic

From Critical Care Medicine. In this article, authors found that survivors of critical illness related to coronavirus disease 2019 are at high risk of developing postintensive care syndrome.


Online Letter to the Editor: Is Mortality Rate of Ventilated Patients With Coronavirus Disease 2019 So High?

From Critical Care Medicine.  This is an online Letter to the Editor in response to “De Novo Renal Failure and Clinical Outcomes of Patients With Critical Coronavirus Disease 2019” by Forest et al.


Online Letter to the Editor: Potential Endotype Transition for Coronavirus Disease 2019–Related Sepsis With Longitudinal Transcriptome Profiling

From Critical Care Medicine. This an online Letter to the Editor in response to the article by Sweeney et al. “Validation of Inflammopathic, Adaptive, and Coagulopathic Sepsis Endotypes in Coronavirus disease 2019."


Online Letter to the Editor: Plasmapheresis Efficiency in Coronavirus Disease 2019: More Related to What You Add and Not What You Take Away?

From Critical Care Medicine. This is an online Letter to the Editor in response to the article by Fernandez et al. “Plasma Exchange: An Effective Rescue Therapy in Critically Ill Patients With Coronavirus Disease 2019 Infection.”


Thromboelastography Parameters and Platelet Count on Admission to the ICU and the Development of Venous Thromboembolism in Patients With Coronavirus Disease-2019

From Critical Care Explorations. The authors’ data, discussed in this article, did not support the use of thromboelastography to risk stratify critically ill adults with coronavirus disease 2019 for the development of venous thromboembolism or to guide decisions about anticoagulation.


Changes in Stress and Workplace Shortages Reported by U.S. Critical Care Physicians Treating Coronavirus Disease 2019 Patients

From Critical Care Medicine. In this study, the authors found that stress, staffing, and, to a lesser degree, personal protective equipment shortages faced by U.S. critical care physicians remain high, with stress levels higher among women.


A Systematic Review of the Incidence and Outcomes of In-Hospital Cardiac Arrests in Patients With Coronavirus Disease 2019

From Critical Care Medicine. The authors investigated the incidence, characteristics, and outcomes of in-hospital cardiac arrest in patients with coronavirus disease 2019 and describe the characteristics and outcomes for patients with in-hospital cardiac arrest within the ICU, compared with non-ICU patients with in-hospital cardiac arrest.


Severe Acute Respiratory Syndrome–Associated Coronavirus 2 Infection and Organ Dysfunction in the

From Critical Care Explorations. In this review article, the authors summarize the current state of research in coronavirus disease 2019 pathophysiology within the context of potential organ-based disease mechanisms and opportunities for translational research.


Rapid Development of a Tool for Prioritizing Patients with Coronavirus Disease 2019 for Intensive Care

From Critical Care Explorations. In this study, the authors share a new approach for rapidly developing a decision-support tool for prioritizing patients with coronavirus 2019 disease for admission to ICUs.


ICU Bed Utilization During the Coronavirus Disease 2019 Pandemic in a Multistate Analysis—March to June 2020

From Critical Care Explorations. The authors examined ICU census trends in relation to ICU bed capacity during the rapid increase in severe coronavirus disease 2019 cases early during the pandemic, and concluded they concluded tha ttheir findings demonstrate the short-term adaptability of U.S. healthcare institutions in redirecting limited resources to accommodate a public health emergency.


Detection and Profiling of Human Coronavirus Immunoglobulins in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Explorations. The authors performed anticoronavirus immunoglobulin G profiling of critically ill coronavirus disease 2019 patients to better define their underlying humoral response.


ABCDEF Bundle and Supportive ICU Practices for Patients With Coronavirus Disease 2019 Infection: An International Point Prevalence Study

From Critical Care Explorations. This point prevalence study showed low implementation of the ABCDEF bundle for patients with COVID-19.


Physiologic Improvement in Respiratory Acidosis Using Extracorporeal Co2 Removal With Hemolung Respiratory Assist System in the Management of Severe Respiratory Failure From Coronavirus Disease 2019

From Critical Care Explorations. In this retrospective case series of 29 patients, the authors demonstrated efficacy of extracorporeal Co2 removal using the Hemolung Respiratory Assist System to improve respiratory acidosis in patients with severe hypercapnic respiratory failure due to coronavirus disease 2019.


Collaboration Between Tele-ICU Programs Has the Potential to Rapidly Increase the Availability of Critical Care Physicians—Our Experience Was During Coronavirus Disease 2019 Nomenclature

From Critical Care Explorations.  The authors describe implementing a connected network between two tele-ICU programs to support staffing and rounding during the first wave of the coronavirus disease 2019 pandemic in the United States.


Standard Sedation and Sedation With Isoflurane in Mechanically Ventilated Patients With Coronavirus Disease 2019

From Critical Care Explorations. The authors describe sedative and analgesic drug utilization in a cohort of critically ill patients with coronavirus disease 2019 and compare standard sedation with an alternative approach using inhaled isoflurane.


Virtual Communication Embedded Bedside ICU Rounds: A Hybrid Rounds Practice Adapted to the Coronavirus Pandemic

From Pediatric Critical Care Medicine. In this article, the authors found that hybrid rounds employed during pandemic facilitated social distancing while retaining patient-centered multidisciplinary ICU rounds but compromised teaching during rounds.


Online Letter to the Editor: Early Percutaneous Tracheostomy in the Coronavirus Disease 2019 Era: Shining New Light on Old Questions

From Critical Care Medicine. In this Online Letter to the Editor, the authors comment on an article by Rosano et al. in which it was demonstrated that early tracheostomy can be performed with acceptable safety in the midst of a pandemic and note that the study raises important questions related to the downsides of routinely performing tracheostomy, tailoring timing of tracheostomy and optimal protocols for decannulation.


Live Tweeting the Discovery of a New Coronavirus Disease 2019–Related Syndrome in Children

From Pediatric Critical Care Medicine. The authors of this Editorial sought to assess the evolving discussion surrounding the naming of a novel pediatric hyperinflammatory syndrome – a condition that showed overlapping features of Kawasaki disease and toxic shock syndrome -- through the analysis of its evolution around the Twitter hashtag #PedsICU.


First and Second Waves of Coronavirus Disease 2019 in Madrid, Spain: Clinical Characteristics and Hematological Risk Factors Associated With Critical/Fatal Illness

From Critical Care Explorations  In this study, the authors sought to determine similarities and differences in clinical characteristics between the patients from two waves of severe acute respiratory syndrome coronavirus-2 infection at the time of hospital admission, as well as to identify risk biomarkers of coronavirus disease 2019 severity.


Prone Positioning and Survival in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Respiratory Failure

From Critical Care Medicine In this study, the authors found that in-hospital mortality was lower in mechanically ventilated hypoxemic patients with coronavirus disease 2019 treated with early proning compared with patients whose treatment did not include early proning.


Best of SCCM Congress Hosted Program

The Best of SCCM Congress program delivers the most popular sessions from SCCM’s Critical Care Congress.


Choosing Wisely in Critical Care

Ten Things Clinicians and Patients Should Question


Concise Critical Appraisal: Asynchronous and Distance Learning in the Age of COVID-19 and Beyond

The medical community has faced many challenges as a result of the COVID-19 pandemic, including ensuring continued medical education in the face of social distancing guidelines and the increased workloads of faculty and trainees. This Concise Critical Appraisal explores an article published in ATS Scholar that sought to outline distance learning options and develop a practical framework for transitioning content to a virtual platform.



When should extracorporeal membrane oxygenation be initiated?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


What are some resources for non-ICU clinicians who are interested in learning more about critical illness related to COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


What is the most appropriate ventilation mode for patients with COVID-19 and how long should patients be on that ventilation mode?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


What is the role of ivermectin in the treatment of COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


Which populations should be anticoagulated? What is the procedure for anticoagulation and how long should it take?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021
 


What is the most appropriate treatment for patients (both inpatients and outpatients) who have a positive polymerase chain reaction test but no symptoms?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


When are steroids indicated for COVID-19? What is the appropriate dosage and duration?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


What is the current role of tocilizumab?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


Can children be anticoagulated or only adults?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


Can antiplatelets be administered at the same time as anticoagulation in patients with COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


Do you have any comments about patients on  clopidogrel who had COVID-19 and developed ischemic stroke secondary to embolic thrombosis?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


Which patients should be proned and for how long?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


What are the recommendations for protection of healthcare professionals who perform aerosolized procedures?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


In a patient who has COVID-19 respiratory infection and requires intubation, when should the patient be intubated and what is the intubation process?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


How should patients be weaned off mechanical ventilation? When should they be weaned and how long should weaning take?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021


What is your recommendation on use of neuromuscular blockade?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021.


The Role of Aspirin for the Treatment of SARS-CoV-2

This resource details the role of aspirin when treating COVID-19 patients.


Baricitinib- The Second ACTT​

This resource details ultilizing baricitinib when treating COVID-19 patients.


Pressure Injury Prevention and Management in COVID-19 patients

This resource details pressure injuries seen with COVID-19 patients.


Transmission of Severe Acute Respiratory Syndrome Coronavirus 1 and Severe Acute Respiratory Syndrome Coronavirus 2 During Aerosol-Generating Procedures in Critical Care: A Systematic Review and Meta-Analysis of Observational Studies

From Critical Care Medicine. In this study, the authors found that personal protective equipment reduce the odds of contracting severe acute respiratory syndrome coronavirus 1 and severe acute respiratory syndrome coronavirus 2.


Efficacy of Serum Angiotensin II Levels in Prognosis of Patients With Coronavirus Disease 2019

From Critical Care Medicine. In this study, the authors found that serum angiotensin II levels decrease significantly in patients with coronavirus disease 2019, and this decrease is correlated with lung damage.


Cardiovascular Disease and Severe Hypoxemia Are Associated With Higher Rates of Noninvasive Respiratory Support Failure in Coronavirus Disease 2019 Pneumonia

From Critical Care Explorations. The authors describe outcomes with high-flow oxygen delivered through nasal cannula and noninvasive positive pressure ventilation in coronavirus disease 2019 acute hypoxemic respiratory failure and identify individual factors associated with noninvasive respiratory support failure.


Editorial: The Complex Issue of Race and Coronavirus Disease 2019 in the ICU

From Critical Care Medicine. In this editorial, the authors discuss the article Racial Differences in a Detroit, MI, ICU Population of Coronavirus Disease 2019 Patients by Lazar et al. about healthcare inequalities and  disparate outcomes.


The Lived Experience of ICU Clinicians During the Coronavirus Disease 2019 Outbreak: A Qualitative Study

From Critical Care Medicine. In this qualitative study, the authors found that, among ICU clinicians, there was a sense of total professional engagement during the surge. Caring for critically ill coronavirus disease 2019 patients was fraught with challenges, and that the experience generated strong feelings of responsibility, as clinicians felt they had to compensate for the absence of family members.


D-dimer and Death in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Medicine.  In a large multicenter cohort study of critically ill patients with coronavirus disease 2019, the authors found higher D-dimer levels were independently associated with a greater risk of death.


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