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Online Letter to the Editor: Postcoronavirus Disease Chronic Fatigue Is Frequent and Not Only Restricted to Hospitalized Patients

From Critical Care Medicine. This Online Letter to the Editor was written in response to a paper by Martillo et al. entitled Postintensive Care Syndrome in Survivors of Critical Illness Related to Coronavirus Disease 2019: Cohort Study From a New York City Critical Care Recovery Clinic,’ in which the authors reported a high-proportion of patients suffering from chronic fatigue 1 month after discharge from hospital for ICU-treated coronavirus disease 2019.


Online Letter to the Editor: Potential Endotype Transition for Coronavirus Disease 2019–Related Sepsis With Longitudinal Transcriptome Profiling

From Critical Care Medicine. This an online Letter to the Editor in response to the article by Sweeney et al. “Validation of Inflammopathic, Adaptive, and Coagulopathic Sepsis Endotypes in Coronavirus disease 2019."


Online Letter to the Editor: Reasons for the Overuse of Sedatives and Deep Sedation for Mechanically Ventilated Coronavirus Disease 2019 Patients

From Critical Care Medicine. This Online Letter to the Editor was written in response to an article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019-Related Acute Respiratory Distress Syndrome: A Retrospective Cohort Study.”


Online Letter to the Editor: Resuscitation and Coronavirus Disease 2019: A Reappraisal

From Critical Care Medicine. This online letter to the editor was written in response to the article “Is Cardiopulmonary Resuscitation Futile in Coronavirus Disease 2019 Patients Experiencing In-Hospital Cardiac Arrest? By Shah et al.


Online Letter to the Editor: The Intriguing, Still Undercovered, Clinical Role of Echocardiography in Critically Ill Coronavirus Disease Patients

From Critical Care Medicine. This Online Letter to the Editor was written in response to an article by  Chotalia et al. entitled “Right ventricular dysfunction and its association with mortality in coronavirus disease 2019 acute respiratory distress syndrome.”


Online Letter to the Editor: The Janus Face of Coronavirus Disease 2019–Associated Coagulopathy

From Critical Care Medicine. This Online Letter to the Editor is in response to an article by Doyle et al. entitled “A comparison of thrombosis and hemorrhage rates in patients with severe respiratory failure due to coronavirus disease 2019 and influenza requiring extracorporeal membrane oxygenation.”


Online Letter to the Editor: The Limitations of Standardized Mortality Ratios for Coronavirus Disease 2019 ICU Patients

From Critical Care Medicine. In this Online Letter to the Editor, the authors discuss the article by Higgins et al. entitled “Coronavirus Disease 2019 ICU Patients Have Higher-Than-Expected Acute Physiology and Chronic Health Evaluation-Adjusted Mortality and Length of Stay Than Viral Pneumonia ICU Patients.”


Online Letter to the Editor: Understanding the Underlying Mechanisms of Hyponatremia in Coronavirus Disease 2019 Is Critical Since Treatment Varies Based on Etiology: Let Us Not Forget Critical Illness-Related Corticosteroid Insufficiency As the Treatment

From Critical Care Medicine. In this Online Letter to the Editor, the authors write in response to an article by Frontera et al. in Critical Care Medicine about etiology of hyponatremia in coronavirus disease 2019 (COVID-19) patients.


Operationalizing Ethical Guidance for Ventilator Allocation in Minnesota: Saving the Most Lives or Exacerbating Health Disparities?

From Critical Care Explorations. In this article, the authors note that the Ventilator Allocation Score can accurately identify patients with high rates of short-term mortality. However, these high mortality patients only represent 27% of all the patients who died, limiting the utility of the score for allocation of scarce resources. The score may unfairly prioritize older patients and inadvertently exacerbate racial health disparities through the inclusion of specific comorbidities such as end stage renal disease. Triage frameworks that include age should be considered. Purposeful efforts, the authors say, must be taken to ensure that triage protocols do not perpetuate or exacerbate prevailing inequities.


Outcome Improvement Between the First Two Waves of the Coronavirus Disease 2019 Pandemic in a Single Tertiary-Care Hospital in Belgium

From Critical Care Explorations.  In this article, the authors note that the main therapeutic changes between the first wave of the coronavirus disease 2019 pandemic and the second wave of the coronavirus disease 2019 pandemic were use of steroids, unrestrictive use of high-flow nasal oxygen for hypoxemic patients, and transfer of patients to other geographic areas in the case of ICU overcrowding. They found that these changes were associated with a decrease in 30-day mortality, ICU admission, and organ support.


Outcomes of Patients With COVID-19 Receiving Organ Support Therapies: The International VIRUS Registry

From Critical Care Medicine. The authors describe the outcomes of hospitalized patients in a multicenter, international coronavirus disease 2019 registry.


Pandemic-Related Submissions: The Challenge of Discerning Signal Amidst Noise

From Critical Care Medicine. The editors of Critical Care Medicine discuss the challenge during current pandemic of discerning data from anecdote, information from observation, and ultimately signal amidst noise.


Patient & Family Communication

This presentation is an overview of communicating strategies for dealing with COVID-19 patients and their families. This is SCCM curated COVID-19 microlearning content.


Paved With Good Intentions: Hospital Visitation Restrictions in the Age of Coronavirus Disease 2019

From Pediatric Critical Care Medicine. Using their experience in a pediatric intensive care unit, the authors surveyed the shortcomings of current visitation restrictions.


Pediatric concerns: Symptoms, diagnosis and mortality

This presentation is an overview of symptoms, diagnosis and mortality concerns seen when treating pediatric patients with COVID-19. This is SCCM curated COVID-19 microlearning content.


Pediatric Critical Care Medicine in the COVID-19 Pandemic

From Pediatric Critical Care Medicine. A foreword from the editors of PCCM about COVID-19 and the journal.


Pediatric Multisystem Inflammatory Syndrome

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 13, 2020.


Pediatric Resuscitation Practices During the Coronavirus Disease 2019 Pandemic

From Pediatric Critical Care Medicine. The authors conducted a survey and found that most U.S. pediatric institutions rapidly adapted their resuscitation systems and practices in response to the coronavirus disease 2019 pandemic.


Percutaneous Dilational Tracheostomy for Coronavirus Disease 2019 Patients Requiring Mechanical Ventilation

From Critical Care Medicine. The authors assess the impact of percutaneous dilational tracheostomy in coronavirus disease 2019 patients requiring mechanical ventilation and the risk for healthcare providers.


Percutaneous Tracheostomy With Apnea During Coronavirus Disease 2019 Era: A Protocol and Brief Report of Cases

From Critical Care Explorations. The authors sought to modify their current procedure for performing percutaneous tracheostomy to minimize aerosolization in hopes that it would help reduce exposure to staff involved. They concluded that percutaneous tracheostomy performed with apnea protocol may help minimize aerosolization, reducing risk of exposure of COVID19 to staff.


Performance Analysis of the National Early Warning Score and Modified Early Warning Score in the Adaptive COVID-19 Treatment Trial Cohort

From Critical Care Explorations.  In this study, the authors sought to validate prognostic scores in coronavirus disease 2019 including National Early Warning Score, Modified Early Warning Score, and age-based modifications, and define their performance characteristics.


Persevering With Prone Ventilation in Coronavirus Disease 2019 Pneumonia

From Critical Care Explorations. In this case study, the authors present a 53-year-old patient with a severe coronavirus disease 2019 pneumonia who has made a remarkable recovery after a difficult period on intensive care.


Perspective of the Surviving Sepsis Campaign on the Management of Pediatric Sepsis in the Era of Coronavirus Disease 2019

From Pediatric Critical Care Medicine. In this article, the authors discuss the Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-associated Organ Dysfunction in Children as they relate to COVID-19.


Pharmacotherapy in Coronavirus Disease 2019 and Risk of Secondary Infections: A Single-Center Case Series and Narrative Review

From Critical Care Explorations. The authors sought to evaluate the impact of pharmacologic approach to coronavirus disease 2019 within the ICU on secondary infections and clinical outcomes.


Physiologic Improvement in Respiratory Acidosis Using Extracorporeal Co2 Removal With Hemolung Respiratory Assist System in the Management of Severe Respiratory Failure From Coronavirus Disease 2019

From Critical Care Explorations. In this retrospective case series of 29 patients, the authors demonstrated efficacy of extracorporeal Co2 removal using the Hemolung Respiratory Assist System to improve respiratory acidosis in patients with severe hypercapnic respiratory failure due to coronavirus disease 2019.


Physiologic Response to Angiotensin II Treatment for Coronavirus Disease 2019–Induced Vasodilatory Shock: A Retrospective Matched Cohort Study

From Critical Care Explorations. In this study, the authors found that angiotensin-II treatment for coronavirus disease 2019–induced distributive shock was associated with rapid improvement in multiple physiologic indices and that angiotensin-II in coronavirus disease 2019–induced shock warrants further study.


Placenta-Derived Cell Therapy to Treat Patients With Respiratory Failure Due to Coronavirus Disease 2019

From Critical Care Explorations. The authors sought to determinewhether placental cell therapy PLacental eXpanded (PLX)-PAD (Pluristem Therapeutics, Haifa, Israel) was beneficial to treating critically ill patients suffering from acute respiratory distress syndrome due to coronavirus disease 2019.
 


Plasma Exchange: An Effective Rescue Therapy in Critically Ill Patients With Coronavirus Disease 2019 Infection

From Critical Care Medicine. In this single center study, the authors found that plasma exchange mitigates cytokine storm, reverses organ failure, and could improve survival in critically ill patients with coronavirus disease 2019 infection.
 


Point-of-Care Lung Ultrasound for Detecting Severe Presentations of Coronavirus Disease 2019 in the Emergency Department: A Retrospective Analysis

From Critical Care Explorations. In this study, lung ultrasound diagnosed severe presentations of coronavirus disease 2019 with similar sensitivity to chest radiograph, CT, and reverse transcriptase-polymerase chain reaction (on first testing) and improved specificity compared to chest radiograph.
 


Point-of-Care Ultrasound for COVID-19 Pneumonia Patients in the ICU

This is an article that details point of care ultrasound for COVID-19 pneumonia. This is a community developed COVID-19 microlearning resource.


Portable Magnetic Resonance Imaging for ICU Patients

From Critical Care Explorations  

In this case series of patients, the authors found use of portable MRI to be safe, feasible, and led to changes in clinical management based on imaging results.


Post-Acute COVID-19 Syndrome

This resource details Post-Acute COVID-19 Syndrome (PASC). This is SCCM curated COVID-19 microlearning content.


Post-Acute Sequelae of COVID-19 (PASC): What Can Be Done in and after the ICU to Lower the Risk of "Long COVID"?

This webinar panel discussed ways to mitigate the risk of post-acute sequelae of COVID-19 (PASC) in hospitalized COVID-19 patients. The panelists and attendees participated in an interactive discussion format with case presentations, polling, and given access to a downloadable infographic to use as a resource tool. The Society of Critical Care Medicine and the American Association of Respiratory Care partnered to produce this webinar on COVID-19. Webcast Recorded on Thursday, April 29, 2021


Post-COVID-19: Considerations From ICU to Discharge (Infographic)

This infographic covers pearls on how to mitigate post-COVID-19: from ICU to discharge. This is SCCM curated COVID-19 microlearning content.


Post-Hospital Treatment of Pain

This resource details the post-hospital treament of pain.

This is SCCM curated COVID-19 microlearning content.


Postintensive Care Syndrome in Survivors of Critical Illness Related to Coronavirus Disease 2019: Cohort Study From a New York City Critical Care Recovery Clinic

From Critical Care Medicine. In this article, authors found that survivors of critical illness related to coronavirus disease 2019 are at high risk of developing postintensive care syndrome.


Potential for Lung Recruitment and Ventilation-Perfusion Mismatch in Patients With the Acute Respiratory Distress Syndrome From Coronavirus Disease 2019

From Critical Care Medicine. Severe cases of coronavirus disease 2019 develop the acute respiratory distress syndrome, requiring admission to the ICU. This study aims to describe specific pathophysiological characteristics of acute respiratory distress syndrome from coronavirus disease 2019.


Prediction of Pediatric Critical Care Resource Utilization for Disaster Triage

From Pediatric Critical Care Medicine. The authors sought to determine whether currently available pediatric illness severity scores can predict duration of critical care resource use. A pediatric disaster triage algorithm that includes both likelihood for survival and for requiring critical care resources could minimize subjectivity in resource allocation decision-making.


Prediction of Pediatric Critical Care Resource Utilization for Disaster Triage

From Pediatric Critical Care Medicine. The authors sought to determine whether currently available pediatric illness severity scores can predict duration of critical care resource use.


Prepare for a Surge of Pediatric Patients with COVID-19

Learn about ways critical care clinicians can prepare for children returning to school and the upcoming flu season.


Preparedness and Reorganization of Care for Coronavirus Disease 2019 Patients in a Swiss ICU: Characteristics and Outcomes of 129 Patients

From Critical Care Explorations. The authors report their experience in Switzerland with regard to ICU organization and anticipation, as well as patient characteristics, treatment, and outcomes.


Presence of Spontaneous Echo Contrast on Point-of-Care Vascular Ultrasound and the Development of Major Clotting Events in Coronavirus Disease 2019 Patients

From Critical Care Explorations. In this study, the authors assessed for the prevalence and consequences of spontaneous echo contrast on point-of-care vascular ultrasound in coronavirus disease 2019.


Pressure Injuries (Infographic)

This resource is an infographic detailing pressure injuries. This is SCCM curated COVID-19 microlearning content.


Pressure Injury Prevention and Management in COVID-19 patients

This resource details pressure injuries seen with COVID-19 patients.


Prevalence and Impact of Hyponatremia in Patients With Coronavirus Disease 2019 in New York City

From Critical Care Medicine. In this study from New York, NY, the authors found that hyponatremia occurred in nearly a third of coronavirus disease 2019 patients, was an independent predictor of in-hospital mortality, and was associated with increased risk of encephalopathy and mechanical ventilation.
 


Prevalence of Thrombotic Complications in ICU-Treated Patients With Coronavirus Disease 2019 Detected With Systematic CT Scanning

From Critical Care Medicine. In this study, the authors looked for the true prevalence of thrombotic complications in critically ill patients with severe coronavirus disease 2019 on the ICU, with or without extracorporeal membrane oxygenation.


Preventing Skin Injuries from Long-Term Prone Positioning

This resource detail how to prevent skin injuries due to long-term proning. This is SCCM curated COVID-19 microlearning content.


Principles Guiding Nonpandemic Critical Care Research During a Pandemic

From Critical Care Medicine. In this article, the authors describe the importance of critical care clinical research that is not pandemic-focused during pandemic times; outline principles to assist in the prioritization of nonpandemic research during pandemic times; and propose a guiding framework for decisions about whether, when and how to continue nonpandemic research while still honoring the moral and scientific imperative to launch research that is pandemic-focused.


Probative Value of the D-Dimer Assay for Diagnosis of Deep Venous Thrombosis in the Coronavirus Disease 2019 Syndrome

From Critical Care Medicine.The authors describe the predictive utility of the D-dimer assay among patients with the coronavirus disease 2019 syndrome for unprovoked lower extremity deep venous thrombosis.


Procalcitonin Exerts a Mediator Role in Septic Shock Through the Calcitonin Gene-Related Peptide Receptor

From Critical Care Medicine

The authors found that procalcitonin exerts a moderate but harmful effect on disease progression in experimental septic shock, and suggests a potential therapeutic application for calcitonin gene-related peptide receptor inhibitors in sepsis.


Procedures for COVID-19 Cohort Units: Building an Operating Room in a COVID-19 Cohort ICU

This presentation provides procedures for building COVID-19 cohort units. This is SCCM curated COVID-19 microlearning content.


Process Adaptations for Airway Management in COVID patients

This is an infographic that details process adaptations for airwary management. This is a community developed COVID-19 microlearning resource.


Prognostic Factors for 30-Day Mortality in Critically Ill Patients With Coronavirus Disease 2019: An Observational Cohort Study

From Critical Care Medicine

The authors identified patient characteristics that predict an increased likelihood of death within 30 days of the start of critical care for patients with coronavirus disease 2019, which included age, ethnicity, deprivation, body mass index, and prior dependency, among other characteristics.


Prolonged Anaphylaxis to Pfizer Coronavirus Disease 2019 Vaccine: A Case Report and Mechanism of Action

From Critical Care Explorations. In this case report, the authors describe a case of protracted anaphylaxis in a recipient of the BNT162b2


Promoting Value in Critical Care by Implementing (Next Five) Choosing Wisely For Critical Care; ICU Liberation Bundle (E = Early Mobility)

Overview of the Next 5 Choosing Wisely Statements and how they intersect with the ICU Liberation Bundle. And, overview of the "E" element of the ICU Liberation Bundle. This is SCCM curated COVID-19 microlearning content.

Curriculum Topic: ICU Liberation Bundle Implementation & Challenges


Prone Positioning and Survival in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Respiratory Failure

From Critical Care Medicine In this study, the authors found that in-hospital mortality was lower in mechanically ventilated hypoxemic patients with coronavirus disease 2019 treated with early proning compared with patients whose treatment did not include early proning.


Prone Positioning of Nonintubated Patients With Coronavirus Disease 2019—A Systematic Review and Meta-Analysis

From Critical Care Medicine. In this systematic review and meta-analysis, the authors found that, despite the significant variability in frequency and duration of prone positioning and respiratory supports applied, prone positioning was associated with improvement in oxygenation variables without any reported serious adverse events.


Proper Transport of Patients With COVID-19 From Hospital to Hospital

This presentation is an overview of proper transport procedures of COVID-19 patients. This is SCCM curated COVID-19 microlearning content.


Proper Transport of Patients With COVID-19 Within the Hospital

This presentation is an overview of proper transport procedures of COVID-19 patients. This is SCCM curated COVID-19 microlearning content.


Propofol-Associated Hypertriglyceridemia in Coronavirus Disease 2019 Versus Noncoronavirus Disease 2019 Acute Respiratory Distress Syndrome

From Critical Care Explorations

In this study, the authors found that patients with coronavirus disease 2019 acute respiratory distress syndrome experienced a higher rate of propofol-associated hypertriglyceridemia than noncoronavirus disease 2019 acute respiratory distress syndrome patients, even after accounting for differences in propofol administration.


Proposal for Coronavirus Disease 2019 Management

From Critical Care Explorations. During a pandemic, with limited resources, we should provide the safest and most effective care, while protecting caregivers.The authors propose ways to do that.


Provider Labor Pool Deployment Workflow and Inpatient Competency and Training Guide

This resource is a quick training guide on labor pool deployment workflow and inpatient competency. This is a community developed COVID-19 microlearning resource.


Psychologic Distress and Quality of Life After ICU Treatment for Coronavirus Disease 2019: A Multicenter, Observational Cohort Study

From Critical Care Explorations. In this study, the authors found that psychologic distress was common in coronavirus disease 2019 ICU survivors and remained similar until 6 months after hospital discharge.


Quantification of Neurological Blood-Based Biomarkers in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations. In this study, the authors sought to provide an objective characterization of acute neurologic injury in critically ill patients with coronavirus disease 2019.


Racial Differences in a Detroit, MI, ICU Population of Coronavirus Disease 2019 Patients

From Critical Care Medicine  

Contrary to previously held beliefs surrounding the coronavirus 19 pandemic, this study found that, in critically ill patients infected with coronavirus disease 2019, people of color had a lower 28-day mortality than Whites with no difference in hospital mortality, ICU length of stay, or rates of intubation. 


Ramifications of COVID-19 Pandemic on Pharmacy Daily Workflow

This presentation describes the ramification on daily workflow when working on the frontines during the pandemic. This is SCCM curated COVID-19 microlearning content.


Rapid Development of a Tool for Prioritizing Patients with Coronavirus Disease 2019 for Intensive Care

From Critical Care Explorations. In this study, the authors share a new approach for rapidly developing a decision-support tool for prioritizing patients with coronavirus 2019 disease for admission to ICUs.


Rapid Implementation of Telecritical Care Support During a Pandemic: Lessons Learned During the Coronavirus Disease 2020 Surge in New York City

From Critical Care Explorations

The authors describe key elements for a New York City health system to rapidly implement telecritical care consultative services to a newly created ICU during the coronavirus disease 2020 patient surge.


Rapid Transition of a PICU Space and Staff to Adult Coronavirus Disease 2019 ICU Care

From Critical Care Medicine

The authors describe how a PICU and a PICU care team were incorporated into a hospital-wide ICU care model during the coronavirus disease 2019 pandemic.


Rationale for Prolonged Corticosteroid Treatment in the Acute Respiratory Distress Syndrome Caused by Coronavirus Disease 2019

From Critical Care Explorations. The authors state that inconclusive clinical evidence should not be a reason for abandoning CST in COVID-19-associated ARDS.


Readiness for and Response to Coronavirus Disease 2019 Among Pediatric Healthcare Providers: The Role of Simulation for Pandemics and Other Disasters

From Pediatric Critical Care Medicine

Early preparation for the training and education of healthcare providers, as well as the continuation or modification of routine medical education programs, is of great importance in times of the coronavirus disease 2019 pandemic or other public health emergencies; this study aimed to characterize these self-reported efforts by the pediatric simulation community.


Regarding anticoagulation strategies, is there a role for tissue plasminogen activator (tPA)? If so, what is the indication for it and who would you use it on?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 14, 2021


Regarding anticoagulation, in NHS trusts in the UK, COVID-19 routine blood screening includes D-dimer. They perform a lot of CT pulmonary angiography, which are negative for central pulmonary embolism. What do comparable U.S. data show?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


Regarding multimodality therapies, specifically steroids, what would you administer to a patient with COVID-19 today? If the patient were on remdesivir, would you continue the remdesivir for the full duration of therapy?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 14, 2021


Regarding respiratory support of COVID-19 patients both in and outside the ICU, can you discuss noninvasive ventilation, BiPAP, CPAP, and high-flow nasal cannula versus intubation? What are the indications for intubation? Intubate early or later?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on August 12, 2020.


Relocating IV Pumps for Critically Ill Isolated Coronavirus Disease 2019 Patients From Bedside to Outside the Patient Room

From Critical Care Explorations. The authors discuss advantages and disadvantages of relocating IV pumps for coronavirus disease 2019 patients from bedside to outside the patient room and characterize reproducible details of an external infusion pump model.


Renal Issues Related to COVID-19

This is presentation covers the renal issues that can attributed to COVID-19 infection. This is SCCM curated COVID-19 microlearning content.


Renal Replacement Therapy for COVID-19 Patients

This resource details an the usage of renal replacement therapy for COVID-19 patients.

This is SCCM curated COVID-19 microlearning content.


Renin-Angiotensin System and COVID-19

This presentation is a review of the renin-angiostensin System and COVID-19. This is SCCM curated COVID-19 microlearning content.


Rescue Treatment With High-Dose Gaseous Nitric Oxide in Spontaneously Breathing Patients With Severe Coronavirus Disease 2019

From Critical Care Explorations

The authors present a case series of patients who received nitric oxide inhalation as a rescue therapy for coronavirus disease 2019.


Resolution of Coronavirus Disease 2019 Infection and Pulmonary Pathology With Nebulized DAS181: A Pilot Study

From Critical Care Explorations

The authors investigated the safety and effects of nebulized DAS181 on hypoxic coronavirus disease 2019 patients.


Respiratory Physiology of Prone Positioning With and Without Inhaled Nitric Oxide Across the Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Severity Spectrum

From Critical Care Explorations. In this observational study, the authors found that prone positioning improves oxygenation across the acute positive respiratory distress syndrome severity spectrum, irrespective of supine respiratory system compliance, end-expiratory pressure, or body mass index. There was a greater relative benefit among patients with more severe disease. Prone positioning confers an additive benefit in oxygenation among patients treated with inhaled nitric oxide.


Return to Work After Coronavirus Disease 2019 Acute Respiratory Distress Syndrome and Intensive Care Admission: Prospective, Case Series at 6 Months From Hospital Discharge

From Critical Care Medicine. In this Online Brief Report, the authors describe rates of return to work versus unemployment following coronavirus disease 2019 acute respiratory distress syndrome requiring intensive care admission.


Reversal of the Pathophysiological Responses to Gram-Negative Sepsis by Megadose Vitamin C

From Critical Care Medicine

The authors invesitated the safety and efficacy of megadose sodium ascorbate in sepsis.


Review of Approved Monoclonal Antibody Treatments for COVID-19

This resource details monoclonal antibody treatments that can be used to treat COVID-19.
This is SCCM curated COVID-19 microlearning content.


Review of Viral Testing (Polymerase Chain Reaction) and Antibody/Serology Testing for Severe Acute Respiratory Syndrome-Coronavirus-2 for the Intensivist

From Critical Care Explorations. As the SARS-CoV-2 pandemic develops, assays to detect the virus and infection caused by it are needed for diagnosis and management. In this article, the authors describe to clinicians how each assay is performed, what each assay detects, and the benefits and limitations of each assay.


Right Ventricular Dysfunction and Its Association With Mortality in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome

From Critical Care Medicine  In this article, the authors assessed whether right ventricular dilation or systolic impairment is associated with mortality and/or disease severity in invasively ventilated patients with coronavirus disease 2019 acute respiratory distress syndrome.


Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry

From Critical Care Explorations. In this study, the authors found that, among hospitalized young adults, obese males with comorbidities are at higher risk of developing critical illness or dying from coronavirus disease 2019.


Risk Factors for Invasive Pulmonary Aspergillosis in Critically Ill Patients With Coronavirus Disease 2019-Induced Acute Respiratory Distress Syndrome

From Critical Care Explorations

The authors retrospectively evaluated cases of coronavirus disease 2019 acute respiratory distress syndrome patients and identified six patients that met the diagnosis of invasive pulmonary aspergillosis according to previously established definitions. 


Role for Anti-Cytokine Therapies in Severe Coronavirus Disease 2019

From Critical Care Explorations. In this narrative review, the authors summarize existing knowledge of the immune response to coronavirus infection and highlight the current and potential future roles of therapeutic strategies to combat the hyperinflammatory response of patients with coronavirus disease 2019.


Routine Venous Thromboembolism Prophylaxis May Be Inadequate in the Hypercoagulable State of Severe Coronavirus Disease 2019

From Critical Care Medicine. The authors sought to determine the frequency of venous thromboembolism in critically ill coronavirus disease 2019 patients and associate a degree of inflammatory marker elevation to venous thromboembolism development. They found that routine chemical venous thromboembolism prophylaxis may be inadequate in preventing venous thromboembolism in severe coronavirus disease 2019.


Safety and Feasibility of an Interdisciplinary Treatment Approach to Optimize Recovery From Critical Coronavirus Disease 2019

From Critical Care Explorations. In this study, the authors examined the safety and feasibility of a multimodal in-person or telehealth treatment program, administered in acute recovery phase for patients surviving critical coronavirus disease 2019. They found that multimodal treatment program combining care from an interdisciplinary team in an ICU Recovery Clinic with physical rehabilitation is safe and feasible in patients surviving the ICU for coronavirus disease 2019 acute respiratory failure.


Scaled Pandemic Preparedness: From Large Medical Center to Community Hospital - What Do You Need To Do?

The webcast covered how to prepare for the COVID-19 pandemic, with lessons learned from hospitals in the Houston area that already established special isolation units.


Scarce Resource Allocation in a Pandemic: A Protocol to Promote Equity, Timeliness, and Transparency

From Critical Care Explorations. Drawing on expertise in critical care medicine, bioethics, and political science, the authors propose a decision-making protocol to ensure fairness in the resolution of conflict, timely decision-making, and accountability to improve system response.


SCCM Pod-409 SSC COVID-19 Guidelines

Explore the Surviving Sepsis Campaign’s Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) (Alhazzani W, et al. Crit Care Med. 2020 Mar 27; Epub ahead of print) with host Kyle B. Enfield, MD, and authors Mitchell M. Levy, MD, MCCM, and Waleed Alhazzani, MD, MSc, FRCPC.


SCCM Pod-410 COVID-19 Neurologic Manifestations

Review neurologic manifestations of COVID-19 and other severe respiratory viral contagions (Robinson C, et al. Crit Care Explor. 2020;2:e0107).


SCCM Pod-412 COVID-19 in Critically Ill Children

Gain valuable insight on the clinical management of COVID-19 and its relevance to the pediatric critical care provider (Ong J, et al. Pediatr Crit Care Med. 2020 Apr 7; Epub ahead of print) with host Elizabeth H. Mack, MD, MS, FCCM, and Jacqueline Ong, MB BChir, MMed (Paeds), MRCPCH.


SCCM Pod-413 COVID-19 Fact Versus Science Fiction

Explore the need for randomized COVID-19 clinical trials and the difficulties and potential consequences of misinformation (Ingraham N, et al. Crit Care Explor. 2020;2:e0108) with host Ashish K. Khanna, MD, FCCP, FCCM, and Nicholas E. Ingraham, MD.


SCCM Pod-414 COVID-19 VIRUS Registry Aims to Identify Effective Treatment Strategies

Discovery, the Critical Care Research Network's Viral Infection and Respiratory Illness Universal Study creates a real-time COVID-19 registry of current ICU and hospital care patterns.


SCCM Pod-415 NIH COVID-19 Treatment Guidelines

The National Institutes of Health has released Coronavirus Disease 2019 (COVID-19) Treatment Guidelines.


SCCM Pod-416 COVID-19 Learning: Multiple Patients on a Single Ventilator

In a situation where ventilators are in short supply, multiple patients on a single ventilator could be a strategy of last resort.


SCCM Pod-417 COVID-19-Associated Acute Respiratory Distress Syndrome

Clinicians are working to understand and formulate an effective treatment for COVID-19-associated acute respiratory distress syndrome (Marini J. Crit Care Med. 2020 May 13; Epub ahead of print).


SCCM Pod-418 COVID-19 Learning: Conversion of a Children's Hospital to an Adult Hospital

Montefiore Medical Center in the Bronx, New York, USA, quickly converted a children's hospital to an adult COVID-19 hospital. Hear Margaret M. Parker, MD, MCCM, talk with H. Michael Ushay, MD, PhD, FAAP, FCCM, about the process, challenges with staffing and personal protective equipment, and more.


SCCM Pod-421 COVID-19 and Renal Replacement Therapy

The increase in acute kidney injury in COVID-19 patients is resulting in more utilization of renal replacement therapy (RRT) and continuous renal replacement therapy (CRRT).


SCCM Pod-422 Procalcitonin in COVID-19 and Influenza-Related Secondary Bacterial Infections

Procalcitonin testing on admission seems to be a valuable piece of information for early risk assessment and ruling out bacterial co-infection in COVID-19 patients.


SCCM Pod-423 Coagulopathy in COVID-19 Patients

COVID-19 is associated with a high prevalence of coagulopathy and venous thromboembolism. Host B. Kyle Enfield, MD, FCCM, talks with Jerrold H. Levy, MD, FAHA, FCCM, about what clinicians need to know about this serious problem and how it impacts care delivery (Iba et al. Crit Care Med. 2020;48:1358-1364).


SCCM Pod-427 Severe COVID-19 and Sepsis

Severe COVID-19 infection can be a form of viral sepsis with occasionally concomitant bacterial infection.


SCCM/AARC: Maximizing the Respiratory Team Dynamic: Effective Patient Care During a Pandemic

This expert panel representatives from Society of Critical Care Medicine (SCCM) and the American Association for Respiratory Care (AARC) teamed up to discuss how ICU respiratory care teams can work together more cohesively when caring for COVID-19 patients. Recorded on: Thursday, May 14, 2020


SCCM/ACEP Presidents' Expert Panel: Unanticipated Consequences of Pandemic Care

This joint webinar was moderated by the Society of Critical Care Medicine (SCCM) and the American College of Emergency Physicians (ACEP) Presidents, along with invited experts from both societies, to address difficult questions regarding managing COVID-19 patients.


SCCM’s 50th Critical Care Congress: COVID-19: Global Voices and Perspectives

From SCCM's 50th Critical Care Congress. Critical care professionals from around the world shared their thoughts and perspectives on COVID-19.


SCCM’s 50th Critical Care Congress: Frontline Nursing: Leadership Lessons From the Battlefield to the COVID-19 Crisis

From SCCM's 50th Critical Care Congress. Elizabeth J. Bridges, CCNS, MSN, PhD, RN, highlights lessons learned in frontline nursing during the COVID-19 pandemic and what they mean for the future of leadership.


SCCM’s 50th Critical Care Congress: Public Health Crises: From Measles to COVID-19

From SCCM's 50th Critical Care Congress. New York State Health Commissioner Howard A. Zucker, MD, JD, FCCM, discuss public health directives and policies that have proven effective at managing dangerous spikes in hospitalizations during New York State’s response to recent measles and COVID-19 outbreaks.


SCCM’s 50th Critical Care Congress: Surviving Sepsis Campaign COVID-19 Guidelines Therapeutics Update

From SCCM's 50th Critical Care Congress. Learn more about the guidelines therapeutics update and the methodology and its application to public health emergencies.


SCCM-ASA Joint Statement to Address the COVID-19 Pandemic

COVID-19 - SCCM Joint Statement. The Society of Critical Care Medicine (SCCM) and the American Society of Anesthesiologists (ASA) announce their plans to collaborate to address the COVID-19 crisis.


Sedation Practices

Focus on ABC elements of the ICU Liberation Bundle, specifically, 1) depth of sedation, 2) choosing the right agent, 3) daily interruption of sedation. This is SCCM curated COVID-19 microlearning content.

Curriculum Topic: ICU Liberation Bundle Implementation & Challenges


Sepsis and Coronavirus Disease 2019: Common Features and Anti-Inflammatory Therapeutic Approaches

From Critical Care Medicine. The authors present some common features shared by severe coronavirus disease 2019 patients and sepsis and describe proposed anti-inflammatory therapies for coronavirus disease 2019 which have been previously evaluated in sepsis.
 


Severe Acute Respiratory Syndrome Coronavirus 2 Convalescent Plasma Versus Standard Plasma in Coronavirus Disease 2019 Infected Hospitalized Patients in New York: A Double-Blind Randomized Trial

From Critical Care Medicine. In this study, the authors found that administration of convalescent plasma to hospitalized patients with coronavirus disease 2019 infection increased antibodies to severe acute respiratory syndrome coronavirus disease 2 but was not associated with improved outcome.


Severe Acute Respiratory Syndrome Coronavirus-2 Infections in Critical Care Staff: Beware the Risks Beyond the Bedside

From Critical Care Medicine. In this study, the authors found that staff who developed coronavirus disease 2019 were less likely to have caught it from their patients in critical care. Other staff, other areas of the hospital, and the wider community are more likely sources of infection.


Severe Acute Respiratory Syndrome Coronavirus-2-Associated Acute Kidney Injury: A Narrative Review Focused Upon Pathophysiology

From Critical Care Medicine. In this article, the authors conclude that a personalized approach to each patient with acute kidney injury based on the timing and severity of disease is necessary in order to provide appropriate treatment.


Severe Acute Respiratory Syndrome–Associated Coronavirus 2 Infection and Organ Dysfunction in the

From Critical Care Explorations. In this review article, the authors summarize the current state of research in coronavirus disease 2019 pathophysiology within the context of potential organ-based disease mechanisms and opportunities for translational research.


Should a patient have a negative COVID-19 test before undergoing a tracheostomy?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered.


Should anticoagulation or antiplatelet therapy be used for patients with COVID-19? Should these patients be empirically anticoagulated? How is your institution handling this?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021


Should BiPAP be used in patients with COVID-19 or should it be avoided? If you decide to intubate a patient, which parameters should be used and what initial ventilatory settings do you recommend?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021


Should dexamethasone or remdesivir be started on a patient who requires oxygen via nasal cannula and is highly suspected of having COVID-19 if test results are still pending?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


Should patients on oxygen therapy be discharged home or to a long-term acute care hospital?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 13th, 2020.


Simulation: Keeping Pace With Pandemics

From Pediatric Critical Care Medicine. The authors discuss the immediate need to become quickly prepared for overwhelming patient care and health system needs, and the usefulness of simulation.


Six-Month Pulmonary Function After Venovenous Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019 Patients

From Critical Care Explorations. In this study, the authors observed preserved long-term volumetric lung function with decreased diffusion capacity of lung carbon monoxide among survivors from severe coronavirus disease 2019 pneumonia treated with venovenous extracorporeal membrane oxygenation.


Society of Critical Care Medicine Crisis Standard of Care Recommendations for Triaging Critical Resources During the COVID-19 Pandemic

The purpose of these recommendations is to provide a transparent, equitable, and consistent approach to allocation of scarce resources during a COVID-19-declared emergency in which crisis standards of care have been implemented.


Soluble Suppression of Tumorigenicity-2 Associates With Ventilator Dependence in Coronavirus Disease 2019 Respiratory Failure

From Critical Care Explorations. In this study, the authors hypothesized that elevated soluble suppression of tumorigenicity-2 concentrations, a marker of pulmonary epithelial injury, reflects ongoing lung injury in acute hypoxemic respiratory failure due to coronavirus disease 2019 and associate with continued ventilator dependence.


Spectrum of Vascular Involvement in Coronavirus Disease 2019 Pneumonia—Findings on CT Perfusion

From Critical Care Explorations

In this article, the authors observed and interpreted CT perfusion patterns of COVID-19 pulmonary features.


Standard Sedation and Sedation With Isoflurane in Mechanically Ventilated Patients With Coronavirus Disease 2019

From Critical Care Explorations. The authors describe sedative and analgesic drug utilization in a cohort of critically ill patients with coronavirus disease 2019 and compare standard sedation with an alternative approach using inhaled isoflurane.


Statewide Real-Time Tracking of Beds and Ventilators During Coronavirus Disease 2019 and Beyond

From Critical Care Explorations. This brief report describes the rapid deployment of a real-time electronic tracking board for all hospitals in the state of Oregon.


STOP-VIRUS Learning Community Session

Quality Improvement Concepts and Practice/Implementation Science This is SCCM curated COVID-19 microlearning content.

Curriculum Topic: Quality Improvement Learning Community Session


Strategies During NeuroMuscular Blocking Agent (NMBA) Shortages

This presentation covers how to manage neuromuscular blocking agent (NMBA) shortages. This is SCCM curated COVID-19 microlearning content.


Strategies for approaching SAT in patients with COVID-19

This presentation provides an overview of the types of strategies for approaching the B Element (Spontaneous Awakening Trials: SATs) of the ICU Liberation Bundle in patients with COVID-19. This is SCCM curated COVID-19 microlearning content.


Strategies for SBTs in patients with COVID-19

This presentation provides an overview of the types of strategies for approaching the B Element (Spontaneous Breathing Trials: STBs) of the ICU Liberation Bundlein patients with COVID-19. This is SCCM curated COVID-19 microlearning content.


Strategies to Approach Drug Shortages of Analgesics and Sedatives During COVID-19

This presentation provides an overview of the types of strategies for approaching the C Element (Choice of Analgesia & Sedation) of the ICU Liberation Bundle in patients with COVID-19. This is SCCM curated COVID-19 microlearning content.


Strategies to Optimize ICU Liberation (A to F) Bundle Performance in Critically Ill Adults With Coronavirus Disease 2019

From Critical Care Explorations. The combination of a novel disease, resource limitations, and risks to medical personnel health have created new barriers to implementing the ABCDEF Bundle, a proven ICU care approach that reduces delirium, shortens mechanical ventilation duration, prevents post-ICU syndrome, and reduces healthcare costs.


Subcutaneous Emphysema, Pneumomediastinum, and Pneumothorax in Critically Ill Patients With Coronavirus Disease 2019: A Retrospective Cohort Study

From Critical Care Explorations. In this observational study, the authors describe patients with barotrauma, which appears to be a common complication of severe coronavirus disease 2019. 


Subcutaneous Enoxaparin Safely Facilitates Bedside Sustained Low-Efficiency Hemodialysis in Hypercoagulopathic Coronavirus Disease 2019 Patients - A Proof-of-Principle Trial

This study describes a simple and safe protocol of anticoagulation with low molecular weight heparin (LMWH) in combination with bedside sustained low efficiency hemodialysis (SLED) in COVID-19 patients.


Surge and Mortality in ICUs in New York City’s Public Healthcare System

From Critical Care Medicine. The authors evaluate the impact of ICU surge on mortality and to explore clinical and sociodemographic predictors of mortality.


Surviving Sepsis Campaign COVID-19 Guidelines (Chinese Translation)

COVID-19 Guideline Resource. SCCM has released its Surviving Sepsis Campaign COVID-19 guidelines to manage critically ill adults with COVID-19 in the intensive care unit (ICU).


Surviving Sepsis Campaign COVID-19 Guidelines: Hemodynamics Recommendations Chart

COVID-19 - - Quick Reference Chart. This chart is to be used as a rapid resource when choosing hemodynamic options for managing COVID-19 patients.


Surviving Sepsis Campaign COVID-19 Guidelines: Infection Control & Testing Recommendations Chart

COVID-19 - - Quick Reference Chart. This chart is to be used as a rapid resource regarding infection control and testing when treating COVID-19 patients.


Surviving Sepsis Campaign COVID-19 Guidelines: Therapy Recommendation Chart

COVID-19 - - Quick Reference Chart. This chart is to be used as a rapid resource when choosing therapeutic options for treating COVID-19 patients.


Surviving Sepsis Campaign COVID-19 Guidelines: Ventilation Recommendations Chart

COVID-19 - - Quick Reference Chart. This chart is to be used as a rapid resource when choosing ventilation options for managing COVID-19 patients.


Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19)

Webcast participants were able to learn more about the recommendations included in the guidelines regarding infection control, laboratory diagnosis and specimens, hemodynamic support, ventilatory support


Surviving Sepsis Campaign: Research Priorities for Coronavirus Disease 2019 in Critical Illness

From Critical Care Medicine.  In this article, the authors identify research priorities that represent a roadmap for investigation in COVID-19. 


Technology and Disasters: The Evolution of the National Emergency Tele-Critical Care Network

From Critical Care Medicine. In this Invited Foreword, the authors describe the origins, development, and proof-of-concept testing of the National Emergency Tele-Critical Care Network (NETCCN), a system intended to deliver expertise anywhere needed, at a moment’s notice.


The Association of Inflammatory Cytokines in the Pulmonary Pathophysiology of Respiratory Failure in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations. The authors investigated  the pathophysiological relationship between proinflammatory cytokines and respiratory failure in severe coronavirus disease 2019.


The Association of Preinfection Daily Oral Anticoagulation Use and All-Cause in Hospital Mortality From Novel Coronavirus 2019 at 21 Days: A Retrospective Cohort Study

From Critical Care Explorations. In this retrospective study, the authors sought to understand the association of preinfection daily oral anticoagulation use and the short-term mortality of patients hospitalized with coronavirus disease 2019.


The Characterization of the Toll of Caring for Coronavirus Disease 2019 on ICU Nursing Staff

From Critical Care Explorations. In this brief report, the authors conclude there are indications that registered nurses providing care for coronavirus disease 2019 in the ICU reported increased thermal discomfort coinciding with elevated energy expenditure and a more pronounced self-perception of effort, stress, and mental demand.


The Clinical Presentation and Immunology of Viral Pneumonia and Implications for Management of Coronavirus Disease 2019

From Critical Care Explorations. This article examines the clinical presentation and important immunology of viral pneumonia with a focus on severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019).


The Combination of Tocilizumab and Methylprednisolone Along With Initial Lung Recruitment Strategy in Coronavirus Disease 2019 Patients Requiring Mechanical Ventilation: A Series of 21 Consecutive Cases

From Critical Care Explorations. This articles describes the outcomes with use of a combination of tocilizumab and 34 methylprednisolone administered around the time of endotracheal intubation in patients with 35 confirmed COVID-19-associated hypoxemic respiratory failure requiring mechanical ventilation.


The Effects of ICU Crisis Reorganization on Outcomes in Patients Not Infected With Coronavirus Disease 2019 During the Initial Surge of the Coronavirus Disease 2019 Pandemic

From Critical Care Explorations. In this study, the authors determined if ICU reorganization due to the coronavirus disease 2019 pandemic affected outcomes in critically ill patients who were not infected with coronavirus disease 2019.


The Impact of the Novel Coronavirus on Brazilian PICUs

From Pediatric Critical Care Medicine. The authors evaluated the impact of the coronavirus disease 2019 pandemic, considering the physical distancing and schools closing, on the characteristics of admission and epidemiology on Brazilian PICUs.
 


The Impact of Coronavirus Disease 2019 Pandemic on U.S. and Canadian PICUs

From Pediatric Critical Care Medicine. This study found that patients with coronavirus disease 2019 have a high frequency of comorbidities, require longer stays, more ventilatory support than usual PICU admissions, suggesting several avenues for further exploration.


The Initial Impact of the Coronavirus Disease 2019 Pandemic on ICU Family Engagement: Lessons Learned From a Collaborative of 27 ICUs

From Critical Care Explorations. While the collaborative model can help promote ICU family engagement initiatives, the authors found that coronavirus disease 2019 has impeded implementation of these initiatives even among motivated units.


The Lived Experience of ICU Clinicians During the Coronavirus Disease 2019 Outbreak: A Qualitative Study

From Critical Care Medicine. In this qualitative study, the authors found that, among ICU clinicians, there was a sense of total professional engagement during the surge. Caring for critically ill coronavirus disease 2019 patients was fraught with challenges, and that the experience generated strong feelings of responsibility, as clinicians felt they had to compensate for the absence of family members.


The Need for Continued Compassion in Healthcare Beyond COVID-19

This resource details how compassion in healthcare has changed with COVID-19. This is a community developed COVID-19 microlearning resource.


The POSITIONED Study: Prone Positioning in Nonventilated Coronavirus Disease 2019 Patients - A Retrospective Analysis

From Critical Care Explorations. In this study, the authors investigated explored whether awake self-proning improved outcomes in coronavirus disease 2019-infected patients treated in a rural medical center with limited resources during a significant local coronavirus disease 2019 outbreak.


The primary cause of gas exchange impairment in COVID-19 is thought to be different from regular acute respiratory distress syndrome (ARDS). There has been controversy regarding inhaled nitric oxide.

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on January 13, 2021


The Rationale for the Use of Prolonged Corticosteroid Treatment for ARDS Caused by COVID-19

Steve Pastores, MD, co-author of the Critical Care Explorations article "Rationale for Prolonged Corticosteroid Treatment in the Acute Respiratory Distress Syndrome Caused by Coronavirus Disease 2019," discusses the use of corticosteriod treatment for ARDS caused by COVID-19. This is SCCM curated COVID-19 microlearning content.


The Role of Aspirin for the Treatment of SARS-CoV-2

This resource details the role of aspirin when treating COVID-19 patients.


The Ties That Bind: A Coronavirus Disease Journey

From Critical Care Explorations

In this article, the authors describe a personal experience of COVID-19 bringing two old friends together and the patient care lessons learned.


The Use of High-Flow Nasal Oxygen in the ICU as a First-Line Therapy for Acute Hypoxemic Respiratory Failure Secondary to Coronavirus Disease 2019

From Critical Care Explorations

The authors characterize outcomes associated with high-flow nasal oxygen use in critically ill adult patients with coronavirus disease 2019-associated acute hypoxemic respiratory failure.


The Viral Infection and Respiratory Illness Universal Study (VIRUS): An International Registry of Coronavirus 2019-Related Critical Illness

From Critical Care Explorations. This article describes the conception and implementation of an intensive care database rapidly developed and designed to meet data analytic needs in response to the coronavirus disease 2019 pandemic - the multicenter, international Society of Critical Care Medicine Discovery Network Viral Infection and Respiratory Illness Universal Study.


Three-Dimensional Printed Ventilators: A Rapid Solution to Coronavirus Disease 2019–Induced Supply-Chain Shortages

From Critical Care Explorations. In this paper, the authors report that three-dimensional printed ventilators, such as "CRISIS," propose a potential solution to increase the available number of vents for the United States and abroad, one that is dynamic and able to absorb the massive influx of hospitalized patients for the foreseeable future.


Thromboelastography Parameters and Platelet Count on Admission to the ICU and the Development of Venous Thromboembolism in Patients With Coronavirus Disease-2019

From Critical Care Explorations. The authors’ data, discussed in this article, did not support the use of thromboelastography to risk stratify critically ill adults with coronavirus disease 2019 for the development of venous thromboembolism or to guide decisions about anticoagulation.


Thromboelastography Profiles of Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Medicine. The authors reviewed thromboelastography studies in critically ill patients with coronavirus disease 2019 to characterize their coagulation states.


Thromboelastography to Detect Hypercoagulability and Reduced Fibrinolysis in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Patients

From Critical Care Explorations. In this study, the authors investigated thromboelastography in patients with coronavirus disease 2019-associated acute respiratory distress syndrome with the goal of characterizing suspected coagulopathy and impaired fibrinolysis.
 


Thromboembolism, Hypercoagulopathy, and Antiphospholipid Antibodies in Critically Ill Coronavirus Disease 2019 Patients: A Before and After Study of Enhanced Anticoagulation

From Critical Care Explorations

In this study, the authors sought to determine the prevalence of thrombotic events, functional coagulation tests, inflammatory biomarkers, and antiphospholipid antibodies before and after enhanced anticoagulation in critically ill coronavirus disease 2019 patients.


Time Course of Evolving Ventilator-Induced Lung Injury: The "Shrinking Baby Lung"

From Critical Care Medicine. This paper introduces and highlights several important and /or novel concepts seldom considered by the practicing intensivist.


Timing of Intubation and In-Hospital Mortality in Patients With Coronavirus Disease 2019

From Critical Care Explorations

The authors examined whether increasing time between admission and intubation was associated with mortality in patients with coronavirus disease 2019 who underwent mechanical ventilation.


Timing of Intubation and Its Implications on Outcomes in Critically Ill Patients With Coronavirus Disease 2019 Infection

From Critical Care Explorations. In this Letter to the Editor, the authors report their findings from an observational study aimed to compare the difference in outcomes of critically ill patients with coronavirus disease 2019 who were intubated early versus later in the disease course.


Timing of Intubation and Mortality Among Critically Ill Coronavirus Disease 2019 Patients: A Single-Center Cohort Study

From Critical Care Medicine. The authors examined the impact of time to intubation and use of high-flow nasal cannula on clinical outcomes in patients with coronavirus disease 2019.


Timing of Intubation in Coronavirus Disease 2019: A Study of Ventilator Mechanics, Imaging, Findings, and Outcomes

From Critical Care Explorations  The authors sought to determine the variation in outcomes and respiratory mechanics between the subjects who are intubated earlier versus later in their coronavirus disease 2019 course.


Timing of Tracheostomy for Prolonged Respiratory Wean in Critically Ill Coronavirus Disease 2019 Patients: A Machine Learning Approach

From Critical Care Explorations

The authors found that the optimal window for consideration of tracheostomy for ventilatory weaning in coronavirus disease 2019 patients is between day 13 and 17.


Timing, Dosing, and Duration Recommendations for the Use of Corticosteroids for COVID-19 Patients

Steve Pastores, MD, co-author of the Critical Care Explorations article "Rationale for Prolonged Corticosteroid Treatment in the Acute Respiratory Distress Syndrome Caused by Coronavirus Disease 2019," discusses the timing, dosing and duration recommendations for the use of corticosteriod treatment for COVID-19. This is SCCM curated COVID-19 microlearning content.


Tocilizumab for Cytokine Storm in COVID-19

This presentation provides an overview of the types of strategies for enhancing sleep in patients with COVID-19. This is SCCM curated COVID-19 microlearning content.


Tocilizumab for the Treatment of Severe COVID-19 Pneumonia in Critically Ill Patients: Trendy or Tried-and-True?

This resource details an the usage of tocilizumab as a treatment for severe COVID-19.
This is SCCM curated COVID-19 microlearning content.


Tokyo and New York: A Study in the Contrasting Effects of Socioeconomic Status on Coronavirus Disease 2019 Outcomes

From Critical Care Explorations. The authors examined the association between socioeconomic status and the rate of coronavirus disease 2019 infections using public data from Tokyo.


Tracheostomy for Coronavirus Disease 2019 Patients on Mechanical Ventilation Should Not Be Arbitrarily Delayed

From Critical Care Medicine. This Editorial accompanies an article by Angel et al. entitled “Tracheostomy for Coronavirus Disease 2019 Patients Requiring Mechanical Ventilation.”


Transmission of Severe Acute Respiratory Syndrome Coronavirus 1 and Severe Acute Respiratory Syndrome Coronavirus 2 During Aerosol-Generating Procedures in Critical Care: A Systematic Review and Meta-Analysis of Observational Studies

From Critical Care Medicine. In this study, the authors found that personal protective equipment reduce the odds of contracting severe acute respiratory syndrome coronavirus 1 and severe acute respiratory syndrome coronavirus 2.


Treatment for Severe Coronavirus Disease 2019 With the Seraph-100 Microbind Affinity Blood Filter

From Critical Care Explorations. The authors sought to determine whether Seraph-100 (Exthera Medical Corporation, Martinez, CA) treatment provides clinical benefit for severe coronavirus disease 2019 cases that require mechanical ventilation and vasopressor support.


Treatments of Moderate and Severe COVID-19 Pneumonia

Antiviral and Immunomodulatory Therapies for COVID-19. This is SCCM curated COVID-19 microlearning content.

Curriculum Topic: Infectious Complications & Management of COVID-19 Infection / Nosocomial


Trends in 28-Day Mortality of Critical Care Patients With Coronavirus Disease 2019 in United Kingdom: A National Cohort Study, March 2020 to January 2021

From Critical Care Medicine. The authors sought to determine whether the previously described trend of improving mortality in people with coronavirus disease 2019 in critical care during the first wave was maintained, plateaued, or reversed during the second wave in United Kingdom, when B117 became the dominant strain.


Trends in ICU Mortality From Coronavirus Disease 2019: A Tale of Three Surges

From Critical Care Medicine. The authors sought to determine the association between time period of hospitalization and hospital mortality among critically ill adults with coronavirus disease 2019.


Triaging Critical Resources During COVID-19

The SCCM Ethics Committee prepared a guide entitled, Standard of Care Recommendations for Triaging Resources During the COVID-19 Pandemic.


Unexpectedly High Frequency of Enterococcal Bloodstream Infections in Coronavirus Disease 2019 Patients Admitted to an Italian ICU: An Observational Study

From Critical Care Medicine

The authors found that coronavirus disease 2019 seemed to increase the frequency of bloodstream infections (particularly Enterococcus-related bloodstream infection) after ICU admission.


Update on COVID Vaccinations for Pediatric Patients

This resource details vaccinations for pediatric patients during the COVID-19 pandemic. This is SCCM curated COVID-19 microlearning content.


Update on Multisystem Inflammatory Syndrome in Children (MIS-C)

This resource details an update on MIS-C during the COVID-19 pandemic. This is SCCM curated COVID-19 microlearning content.


Using Nonheparin Anticoagulant to Treat a Near-Fatal Case With Multiple Venous Thrombotic Lesions During ChAdOx1 nCoV-19 Vaccination-Related Vaccine-Induced Immune Thrombotic Thrombocytopenia

From Critical Care Medicine. The authors describe the successful recovery from multiple and life-threatening venous thrombosis after ChAdOx1 nCoV-19 vaccination.


Using the Surviving Sepsis Coronavirus Disease 2019 Guidelines - Anything New Yet?

From Critical Care Explorations. A letter to the editor of Critical Care Explorations about SSC COVID-19 Guidelines and the need to update these guideines and others regularly to help universally optimize sepsis care due to COVID-19 and help flatten the briskly rising morbidity and mortality curve.


Using Social Media for Rapid Information Dissemination in a Pandemic: #PedsICU and Coronavirus Disease 2019

From Pediatric Critical Care Medicine. In this report, the authors describe the use and impact of a targeted strategy for international collaboration and rapid information dissemination on Twitter among members of the pediatric critical care community during a global pandemic.


Validation of a Crisis Standards of Care Model for Prioritization of Limited Resources During the Coronavirus Disease 2019 Crisis in an Urban, Safety-Net, Academic Medical Center

From Critical Care Medicine. In Massachusetts, triage guidelines were designed based on acute illness and chronic life-limiting conditions. In this study, the authors sought to retrospectively validate this protocol to cohorts of critically ill patients from their hospital.


Validation of Inflammopathic, Adaptive, and Coagulopathic Sepsis Endotypes in Coronavirus Disease 2019

From Critical Care Medicine

The authors tested and found that a previously defined bacterial sepsis endotype classifier recapitulates the same clinical and immunological endotypes in viral sepsis (coronavirus disease 2019).


Variation in Initial U.S. Hospital Responses to the Coronavirus Disease 2019 Pandemic

From Critical Care Medicine. The authors characterize emergency responses across hospitals in the United States over time and in the context of local case rates early in the coronavirus disease 2019 pandemic.


Venous Thromboembolism Events Following Venovenous Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Syndrome Coronavirus 2 Based on CT Scans

From Critical Care Medicine. The authors report a 100% occurrence of venous thromboembolism in critically ill patients supported by venovenous extracorporeal membrane oxygenation for severe acute respiratory syndrome coronavirus 2-related acute respiratory distress syndrome using CT scan imaging despite a high target and close monitoring of anticoagulation.


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