SCCM is updating its SCCM Connect Community. Access to SCCM Connect may be limited until April 23.

On Thursday, October 28, 2021, SCCM will be performing maintenance on our websites. Users may experience intermittent issues when trying to access some functionality of

Discovery VIRUS COVID-19 Registry

A global COVID-19 registry that tracks ICU and hospital care patterns in near real time

visual bubble
visual bubble
visual bubble
visual bubble

Viral Infection and Respiratory Illness Universal Study (VIRUS) is a prospective, cross-sectional, observational study and registry of all eligible adult and pediatric patients who are admitted to a hospital. There is no intervention or patient interaction. Only de-identified data is used for analysis. Identifier: NCT04323787

VIRUS COVID-19 Registry Dashboard



Join the SCCM Connect Discovery Group

Approved sites with IRB approval can join the SCCM Connect Discovery Group. Access includes a discussion board and the ability to connect with other Discovery participants.

This is best way to get regular updates about VIRUS!

Request to join the Discovery SCCM Connect Group


VIRUS COVID-19 Registry Enrollment

Please check whether your site is already enrolled as a VIRUS participating site before enrolling. Then complete the intake form and download the frequently asked questions.

Check the VIRUS Participation List
Complete the Intake Form to Participate
Download VIRUS FAQs

Inclusion Criteria

  • COVID-19 PCR (or other SARS-CoV-2) test positive within 21 days
  • COVID-19 PCR pending
  • COVID-19 high clinical suspicion

Primary Aims

  • Create a real-time COVID-19 registry of current intensive care unit and hospital care patterns to allow evaluation of safety and observational effectiveness of COVID-19 practices
  • Determine practice variations across hospitals


The registry will be essential for near-real-time observational comparative effectiveness studies to determine effective treatment strategies and/or provide meaningful hypotheses for clinical trials.

Institutional Review Board: Waiver of Consent

A waiver of informed consent for data collection is being requested for this study from participating sites. No patients will be contacted, but clinicians participating in the study will be surveyed for feedback and satisfaction. For any questions, contact Vishakha Kumar.

STOP-VIRUS ICU Learning Collaborative

ICUs participating in the VIRUS Registry may also be among the 20 sites participating in the STOP-VIRUS collaborative. For more information about this network of ICUs, its leaders and participants, and the learning material being developed, click here.

visual bubble
visual bubble
visual bubble
visual bubble
visual bubble

VIRUS Investigators 

Discovery, the Critical Care Research Network, is leading the efforts for this global COVID-19 registry. 
Rahul Kashyap, MBA, MD
VIRUS Principal Investigator
Rahul Kashyap, MBA, MD

HCA Healthcare
Nashville, Tennessee, USA
Mayo Clinic
Rochester, Minnesota, USA

Allan J. Walkey, MD, MSc
VIRUS Co-Principal Investigator
Allan J. Walkey, MD, MSc

Boston University
Boston, Massachusettes, USA

Juan Pablo Domecq Garces, MD
VIRUS Co-Principal Investigator
Juan Pablo Domecq Garces, MD

Mayo Clinic Foundation
Rochester, Minnesota, USA

Vishakha Kumar, MD, MBA
VIRUS Co-Principal Investigator
Vishakha Kumar, MD, MBA

Discovery, the Critical Care Research Network
Society of Critical Care Medicine

VIRUS Ancillary Studies

Ancillary study proposals may be submitted for a subset of de-identified data for research purposes by investigators of participating sites in the VIRUS study. 

The proposal submission period is now closed.

Information for Investigators

  • Any conflict of interest with the ancillary study proposal will be disclosed by the reviewers and the investigators.
  • The ancillary study proposals have been kept blinded from the VIRUS core investigator group. The first batch of ancillary proposals will be published once the review period closes and notifications are sent to the investigators.
  • SCCM, including the VIRUS core investigators group, has the first right upon publication of the dataset for the research hypothesis outlined for the VIRUS Study.
  • Study participants can serve on the writing group with the VIRUS core investigators team, if their ancillary study ideas overlap or align with the VIRUS overall project aims.
  • Collaboration (national and international) on ancillary proposal submissions is encouraged.
  • Ancillary proposal approval and data sharing will also depend on data quality and completion of the investigator’s own site data for the VIRUS study.

Ancillary Study Approval Process

Manuscript Approval Process