pediatrics

FDA News Release: FDA Expands Authorization of Two Monoclonal Antibodies for Treatment and Post-Exposure Prevention of COVID-19 to Younger Pediatric Patients, Including Newborns

On December 3, 2021, the U.S. Food and Drug Administration revised the emergency use authorization (EUA) of bamlanivimab and etesevimab (previously authorized for pediatric patients 12 years of age and older weighing at least 40 kilograms, or about 88 pounds), to additionally authorize bamlanivimab and etesivimab administered together for the treatment of mild to moderate COVID-19 in all younger pediatric patients, including newborns, who have a positive COVID-19 test and are at high risk for progression to severe COVID-19, including hospitalization or death. This revision also authorizes bamlanivimab and etesevimab, to be administered together, for post-exposure prophylaxis for prevention of COVID-19 in all pediatric patients, including newborns, at high risk of progression to severe COVID-19, including hospitalization or death. 

Preparing Adult Clinicians to Treat Pediatric Patients: Part 2

As pediatric cases of COVID-19 increase, it is vital to prepare for surges that may overwhelm capacity in pediatric intensive care units (ICUs). Pediatric critical care experts will address questions related caring for critically ill pediatric patients and steps to prepare for the next pediatric surge. We know children are not little adults. Whether you are practicing in an adult ICU environment or are a non-ICU clinician who may benefit from critical care training, this webcast will prepare you to treat critically ill pediatric patients. This webinar was held on October 15, 2021.

Preparing Adult Clinicians to Treat Pediatric Patients

As pediatric cases of COVID-19 increase, it is vital to prepare for surges that may overwhelm capacity in pediatric intensive care units (ICUs). During this FREE webcast, pediatric critical care experts will address questions related caring for critically ill pediatric patients and steps to prepare for the next pediatric surge. We know children are not little adults. Whether you are practicing in an adult ICU environment or are a non-ICU clinician who may benefit from critical care training, this webcast will prepare you to treat critically ill pediatric patients. Webcast Recorded on Wednesday, September 22, 2021

IDSA Resources: Pediatrics

SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Infectious Diseases Society of America (IDSA) COVID-19 Real-Time Learning Network. These resources are categorized as Pediatrics

Prepare for a Surge of Pediatric Patients with COVID-19

Learn about ways critical care clinicians can prepare for children returning to school and the upcoming flu season.

Characterization and Outcomes of Hospitalized Children With Coronavirus Disease 2019: A Report From a Multicenter, Viral Infection and Respiratory Illness Universal Study (Coronavirus Disease 2019) Registry

From Critical Care Medicine. In this observational, multicenter registry of children with coronavirus disease 2019, the authors found that ICU admission was common. Older age, fever, multisystem inflammatory syndrome in children, and seizure disorder were independently associated with ICU admission, and mortality was lower among children than mortality reported in adults.

Multisystem Inflammatory Syndrome in Children

Update on research and evidence in multisystem inflammatory syndrome in children. This is SCCM curated COVID-19 microlearning content.

Curriculum Topic: Cardiovascular Complications: Venous Thromboembolism, Myocarditis, and Shock

Endothelial Dysfunction as a Component of Severe Acute Respiratory Syndrome Coronavirus 2–Related Multisystem Inflammatory Syndrome in Children With Shock

From Critical Care Medicine. In this article, the authors found that endothelial dysfunction is associated with severe acute respiratory syndrome coronavirus 2–related multisystem inflammatory syndrome in children with shock and may constitute one of the underlying mechanisms.

Coronavirus Disease 2019–Associated PICU Admissions: A Report From the Society of Critical Care Medicine Discovery Network Viral Infection and Respiratory Illness Universal Study Registry

From Pediatric Critical Care Medicine. This study delineates significant clinically relevant differences in presentation, explanatory factors, and outcomes among children admitted to PICU with severe acute respiratory syndrome coronavirus 2–related illness stratified by multisystem inflammatory syndrome in children.

Update on Multisystem Inflammatory Syndrome in Children (MIS-C)

This resource details an update on MIS-C during the COVID-19 pandemic. This is SCCM curated COVID-19 microlearning content.

Update on COVID Vaccinations for Pediatric Patients

This resource details vaccinations for pediatric patients during the COVID-19 pandemic. This is SCCM curated COVID-19 microlearning content.

Characteristics of Severe Acute Respiratory Syndrome Coronavirus-2 Infection and Comparison With Influenza in Children Admitted to U.K. PICUs

From Critical Care Explorations. The authors describe the nationwide U.K. PICU experience of severe acute respiratory syndrome coronavirus-2 infection during the first wave of the pandemic and compare this with the critical care course of the 2019 influenza cohort.

Association Between Treatments and Short-Term Biochemical Improvements and Clinical Outcomes in Postsevere Acute Respiratory Syndrome Coronavirus-2 Inflammatory Syndrome

From Pediatric Critical Care Medicine. The authors analyzed the short-term biochemical improvements and clinical outcomes following treatment of children with postsevere acute respiratory syndrome coronavirus-2 inflammatory syndrome (multisystem inflammatory syndrome in children/pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus-2) admitted to U.K. PICUs and collated current treatment guidance from U.K. PICUs.

Virtual Communication Embedded Bedside ICU Rounds: A Hybrid Rounds Practice Adapted to the Coronavirus Pandemic

From Pediatric Critical Care Medicine. In this article, the authors found that hybrid rounds employed during pandemic facilitated social distancing while retaining patient-centered multidisciplinary ICU rounds but compromised teaching during rounds.

Live Tweeting the Discovery of a New Coronavirus Disease 2019–Related Syndrome in Children

From Pediatric Critical Care Medicine. The authors of this Editorial sought to assess the evolving discussion surrounding the naming of a novel pediatric hyperinflammatory syndrome – a condition that showed overlapping features of Kawasaki disease and toxic shock syndrome -- through the analysis of its evolution around the Twitter hashtag #PedsICU.

If a patient was previously positive for either COVID-19, multisystem inflammatory syndrome (MIS) in children (MIS-C), or MIS in adults (MIS-A), and now has high titers, what post-COVID-19 symptoms might that patient have?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021

CDC Resources: Pediatrics

SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Centers for Disease Control and Prevention (CDC). These resources are categorized as Pediatrics

Readiness for and Response to Coronavirus Disease 2019 Among Pediatric Healthcare Providers: The Role of Simulation for Pandemics and Other Disasters

From Pediatric Critical Care Medicine

Early preparation for the training and education of healthcare providers, as well as the continuation or modification of routine medical education programs, is of great importance in times of the coronavirus disease 2019 pandemic or other public health emergencies; this study aimed to characterize these self-reported efforts by the pediatric simulation community.

Would you address some of the latest literature relating to COVID-19 in pediatric and obstetric patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.

A Hybrid Model of Pediatric and Adult Critical Care During the Coronavirus Disease 2019 Surge: The Experience of Two Tertiary Hospitals in London and New York

From Pediatric Critical Care Medicine. In this report, the authors describe the hybrid model implemented at institutions in New York and London and discuss shared experiences, pitfalls, challenges, and adjustments required in caring for both young and older patients.

Caring for Critically Ill Children With Suspected or Proven Coronavirus Disease 2019 Infection: Recommendations by the Scientific Sections’ Collaborative of the European Society of Pediatric and Neonatal Intensive Care

From Pediatric Critical Care Medicine. In this article, the authors review the current clinical knowledge of coronavirus disease 2019 disease in critically ill children and discuss some specific treatment concepts based mainly on expert opinion based on limited experience and the lack completed controlled trials in children at the time of the paper.

Multisystem Inflammatory Syndrome in Children Associated With Coronavirus Disease 2019 in a Children's Hospital in New York City

From Pediatric Critical Care Medicine. In this article, the authors report their experience developing a clinical inpatient protocol for the evaluation, management, and follow-up of patients with multisystem inflammatory syndrome.

Delayed Development of Coronary Artery Dilitation in Suspected Severe Acute Respiratory Syndrome Coronavirus 2 Multisystem Inflammatory Syndrome: More Research Needed

From Critical Care Explorations. In this case report, the authors describe a pediatric patient with coronavirus disease-19-associated multisystem inflammatory syndrome without robust hyperinflammation and a delayed finding of coronary artery dilatation, which they believe highlights the need for further mechanistic understanding of coronavirus disease-19 disease and subsequent multisystem inflammatory syndrome in children or Kawasaki disease development.

Convalescent Plasma Therapy in Four Critically Ill Pediatric Patients With Coronavirus Disease 2019: A Case Series

From Critical Care Explorations. In this case report, the authors report a series of four critically ill pediatric patients with acute respiratory failure who received coronavirus disease 2019 convalescent plasma as a treatment strategy for severe disease.

The Impact of the Novel Coronavirus on Brazilian PICUs

From Pediatric Critical Care Medicine. The authors evaluated the impact of the coronavirus disease 2019 pandemic, considering the physical distancing and schools closing, on the characteristics of admission and epidemiology on Brazilian PICUs.
 

Editorial: Pediatric Sepsis in the Time of Coronavirus Disease 2019

From Pediatric Critical Care Medicine. In this editorial, the author reviews ""Perspectives on Pediatric Sepsis in Patients with COVID-19"" from the Surviving Sepsis Campaign Pediatric Guidelines Taskforce authors.
 

Letter to the Editor: Transforming a PICU Into an Adult ICU During the Coronavirus Disease 2019 Pandemic: Meeting Multiple Needs

From Critical Care Explorations. In this Letter to the Editor, the authors describe the process converting half of their 40-bed PICU into a negative-pressure biocontainment ICU dedicated to adult coronavirus disease 2019 patients within a 1,003-bed academic quaternary hospital.

Editorial: Coronavirus Disease 2019: A Tsunami of Data and a Plethora of Unanswered Questions

From Pediatric Critical Care Medicine. In this editorial, the author discusses issues emerging from the study by Bhumbra et al. (Clinical features of critical coronavirus disease 2019 in children) that are worthy of discussion and further exploration, including the predilection for racial minorities, similarities and differences to sepsis, wide expression of clinical disease, and the conundrum of providing family centered care.

Perspective of the Surviving Sepsis Campaign on the Management of Pediatric Sepsis in the Era of Coronavirus Disease 2019

From Pediatric Critical Care Medicine. In this article, the authors discuss the Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-associated Organ Dysfunction in Children as they relate to COVID-19.

Critical Care for Coronavirus Disease 2019: Perspectives From the PICU to the Medical ICU

From Critical Care Medicine. The authors describe the unique perspective of pediatric intensivists caring for critically ill adults during the coronavirus disease 2019 pandemic.

Letter to the Editor: Coronavirus Disease 2019: Understanding Immunopathogenesis Is the “Holy Grail” to Explain Why Children Have Less Severe Acute Disease

From Pediatric Critical Care Medicine. In this letter to the editor, the authors state that the understanding of the immunopathogenesis of SARS-CoV-2 infection is important not only to understand the epidemiologic and age-related differences in COVID-19, but it is critical for the identification of appropriate treatment, as well as for the development of a highly immunogenic vaccine with low risk of antibody dependent enhancement.

Pediatric Resuscitation Practices During the Coronavirus Disease 2019 Pandemic

From Pediatric Critical Care Medicine. The authors conducted a survey and found that most U.S. pediatric institutions rapidly adapted their resuscitation systems and practices in response to the coronavirus disease 2019 pandemic.

Clinical Features of Critical Coronavirus Disease 2019 in Children

From Pediatric Critical Care Medicine. In this study, the authors observed a greater proportion of hospitalized children requiring mechanical ventilation than has been reported to date; they state that older children, African-American or Hispanic children, and males may be at greater risk for severe illness requiring hospitalization.

The Impact of Coronavirus Disease 2019 Pandemic on U.S. and Canadian PICUs

From Pediatric Critical Care Medicine. This study found that patients with coronavirus disease 2019 have a high frequency of comorbidities, require longer stays, more ventilatory support than usual PICU admissions, suggesting several avenues for further exploration.

Are there any differences in standards of care between adult patients and pediatric or adolescent patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.

SCCM Pod-418 COVID-19 Learning: Conversion of a Children's Hospital to an Adult Hospital

Montefiore Medical Center in the Bronx, New York, USA, quickly converted a children's hospital to an adult COVID-19 hospital. Hear Margaret M. Parker, MD, MCCM, talk with H. Michael Ushay, MD, PhD, FAAP, FCCM, about the process, challenges with staffing and personal protective equipment, and more.

Pediatric Critical Care Medicine in the COVID-19 Pandemic

From Pediatric Critical Care Medicine. A foreword from the editors of PCCM about COVID-19 and the journal.

What is the prevalence of the Kawasaki-like severe multiple inflammatory syndrome in children aged 4 to 6 years old with COVID-19 versus in the general population?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 10th, 2020.

In the first phase of the COVID-19 pandemic, when pediatric ICUs were turned into medical ICUs, how did the pediatric intensive care community manage adult patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 10th, 2020.

COVID-19 Dashboard: North American Pediatric ICUs

This resource details a pediatric ICU dashboard sample for tracking COVID-19. This is a community developed COVID-19 microlearning resource.

Can you discuss pediatric inflammatory conditions?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 13th, 2020.

Editorial: Finding the Right Ethical Framework for PICU Resource Allocation During a Pandemic

From Pediatric Critical Care Medicine. An editorial in response to an article by Killien et al. on resource "Prediction of Pediatric Critical Care Resource Utilization for Disaster Triage," noting that, although uniform use of the version of PELOD-2 proposed by Killien et al. won’t eliminate all variation from resource allocation strategies, finding any common ground in resource triage schemes is an important first step.

Letter to the Editor: The Role of the Pediatric Intensivist in the Coronavirus Disease 2019 Pandemic

From Pediatric Intensive Care Medicine. In this letter to the editor, the authors explore the role of pediatric intensivists, as highly-skilled professionals, in the care of critically ill adults. With adequate guidance by professional societies and adult intensivists, pediatric critical care physicians can provide valuable assistance in the current pandemic and in potential COVID-19 epidemic waves to come.

Letter to the Editor: The Role of Lung Ultrasound in Diagnosis and Follow-Up of Children With Coronavirus Disease 2019

From Pediatric Critical Care Medicine. In this letter to the editor, the authors respond to an article by Ong et al. and recommend lung ultrasound in children with COVID-19 as a means of improving outcomes.

Coronavirus Disease in Children

This presentation covers treating COVID-19 in pediatric patients. This is SCCM curated COVID-19 microlearning content.

COVID Toes and Other Rashes

This presentation cover dermatological conditions seen in COVID-19 patients. This is SCCM curated COVID-19 microlearning content.

Pediatric Multisystem Inflammatory Syndrome

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 13, 2020.

Well-Being During Coronavirus Disease 2019: A PICU Practical Perspective

From Pediatric Critical Care Medicine. The authors outline an approach to practically initiating supportive strategies within the PICU using a well-being approach to improving baseline resilience alongside an acute rescue strategy utilising a peer-support network.

Prediction of Pediatric Critical Care Resource Utilization for Disaster Triage

From Pediatric Critical Care Medicine. The authors sought to determine whether currently available pediatric illness severity scores can predict duration of critical care resource use.

Coronavirus Disease 2019 in Children: An Invisible Threat Which We Cannot Ignore

From Pediatric Critical Care Medicine. Editorial in response to Ong et al. article ("A comprehensive narrative review on the impact and implications of COVID-19 in children"), focusing on the management of those most severely affected, as well as providing some practical suggestions for pediatric intensive care clinicians to prepare should COVID-19 become more virulent in children.

SCCM Pod-412 COVID-19 in Critically Ill Children

Gain valuable insight on the clinical management of COVID-19 and its relevance to the pediatric critical care provider (Ong J, et al. Pediatr Crit Care Med. 2020 Apr 7; Epub ahead of print) with host Elizabeth H. Mack, MD, MS, FCCM, and Jacqueline Ong, MB BChir, MMed (Paeds), MRCPCH.