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Content Type: Articles

Physiologic Response to Angiotensin II Treatment for Coronavirus Disease 2019–Induced Vasodilatory Shock: A Retrospective Matched Cohort Study

From Critical Care Explorations. In this study, the authors found that angiotensin-II treatment for coronavirus disease 2019–induced distributive shock was associated with rapid improvement in multiple physiologic indices and that angiotensin-II in coronavirus disease 2019–ind...

   Estimated Time: 25:46 min Coronavirus, COVID-19, Shock, Therapies

Extracorporeal Membrane Oxygenation Retrieval in Coronavirus Disease 2019: A Case-Series of 19 Patients Supported at a High-Volume Extracorporeal Membrane Oxygenation Center

From Critical Care Explorations. In this observational study, the authors concluded that extracorporeal membrane oxygenation retrieval can rescue young, previously healthy patients with severe coronavirus disease 2019 in whom all the conventional respiratory measures have fail...

   Estimated Time: 15:24 min Coronavirus, COVID-19, ECMO, Therapies

Persevering With Prone Ventilation in Coronavirus Disease 2019 Pneumonia

From Critical Care Explorations. In this case study, the authors present a 53-year-old patient with a severe coronavirus disease 2019 pneumonia who has made a remarkable recovery after a difficult period on intensive care.

   Estimated Time: 09:43 min Case Presentation, Coronavirus, COVID-19, Ventilatory Support

Letter to the Editor: Declines in Mortality Over Time for Critically Ill Adults With Coronavirus Disease 2019

From Critical Care Medicine. In this Letter to the Editor, the authors report an update to a previous study, finding a decline in mortality rates in critically ill patients with COVID-19.

   Estimated Time: 06:30 min Coronavirus, COVID-19, Therapies, Ventilatory Support

Caring for Critically Ill Children With Suspected or Proven Coronavirus Disease 2019 Infection: Recommendations by the Scientific Sections’ Collaborative of the European Society of Pediatric and Neonatal Intensive Care

From Pediatric Critical Care Medicine. In this article, the authors review the current clinical knowledge of coronavirus disease 2019 disease in critically ill children and discuss some specific treatment concepts based mainly on expert opinion based on limited experience and ...

Multisystem Inflammatory Syndrome in Children Associated With Coronavirus Disease 2019 in a Children's Hospital in New York City

From Pediatric Critical Care Medicine. In this article, the authors report their experience developing a clinical inpatient protocol for the evaluation, management, and follow-up of patients with multisystem inflammatory syndrome.

Letter to the Editor: Prevalence and Clinical Correlates of Echo-Estimated Right and Left Heart Filling Pressures in Hospitalized Patients With Coronavirus Disease 2019

From Critical Care Explorations In this Letter to the Editor, the authors discuss their study in which they hypothesized that a significant proportion of coronavirus disease 2019 patients has evidence of pulmonary hypertension associated with elevated left heart filling pressu...

   Estimated Time: 09:59 min Cardiovascular, Coronavirus, COVID-19, Diagnosis and Testing

Clinical Outcomes Following Tocilizumab Administration in Mechanically Ventilated Coronavirus Disease 2019 Patients

From Critical Care Explorations. In this study, the authors examined the outcomes of critically ill coronavirus disease 2019 patients treated with tocilizumab and factors associated with clinical improvement.

   Estimated Time: 23:36 min Coronavirus, COVID-19, Therapies, Ventilatory Support

The POSITIONED Study: Prone Positioning in Nonventilated Coronavirus Disease 2019 Patients - A Retrospective Analysis

From Critical Care Explorations. In this study, the authors investigated explored whether awake self-proning improved outcomes in coronavirus disease 2019-infected patients treated in a rural medical center with limited resources during a significant local coronavirus disease ...

   Estimated Time: 18:16 min ARDS, Coronavirus, COVID-19

Delayed Development of Coronary Artery Dilitation in Suspected Severe Acute Respiratory Syndrome Coronavirus 2 Multisystem Inflammatory Syndrome: More Research Needed

From Critical Care Explorations. In this case report, the authors describe a pediatric patient with coronavirus disease-19-associated multisystem inflammatory syndrome without robust hyperinflammation and a delayed finding of coronary artery dilatation, which they believe high...

   Estimated Time: 13:43 min Coronavirus, COVID-19, Pediatrics

Convalescent Plasma Therapy in Four Critically Ill Pediatric Patients With Coronavirus Disease 2019: A Case Series

From Critical Care Explorations. In this case report, the authors report a series of four critically ill pediatric patients with acute respiratory failure who received coronavirus disease 2019 convalescent plasma as a treatment strategy for severe disease.

   Estimated Time: 19:49 min Coronavirus, COVID-19, Pediatrics, Therapies

Antiviral Dosing Modification for Coronavirus Disease 2019–Infected Patients Receiving Extracorporeal Therapy

From Critical Care Explorations. In this study, the authors gathered available published resources including physicochemical and pharmacokinetic properties and suggest antiviral drug dosing adaptation for coronavirus disease 2019–infected critically ill patients receiving extr...

   Estimated Time: 14:12 min Coronavirus, COVID-19, ECMO, Therapies, Virology

Three-Dimensional Printed Ventilators: A Rapid Solution to Coronavirus Disease 2019–Induced Supply-Chain Shortages

From Critical Care Explorations. In this paper, the authors report that three-dimensional printed ventilators, such as "CRISIS," propose a potential solution to increase the available number of vents for the United States and abroad, one that is dynamic and able to absorb the ...

   Estimated Time: 19:34 min Coronavirus, COVID-19, Resource Allocation, Ventilatory Support

Quantification of Neurological Blood-Based Biomarkers in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations. In this study, the authors sought to provide an objective characterization of acute neurologic injury in critically ill patients with coronavirus disease 2019.

   Estimated Time: 23:50 min Clinical presentations, Coronavirus, COVID-19

The Impact of the Novel Coronavirus on Brazilian PICUs

From Pediatric Critical Care Medicine.  The authors evaluated the impact of the coronavirus disease 2019 pandemic, considering the physical distancing and schools closing, on the characteristics of admission and epidemiology on Brazilian PICUs.  

   Estimated Time: 13:08 Coronavirus, COVID-19, pediatrics

Treatment for Severe Coronavirus Disease 2019 With the Seraph-100 Microbind Affinity Blood Filter

From Critical Care Explorations . The authors sought to determine whether Seraph-100 (Exthera Medical Corporation, Martinez, CA) treatment provides clinical benefit for severe coronavirus disease 2019 cases that require mechanical ventilation and vasopressor support.

Point-of-Care Lung Ultrasound for Detecting Severe Presentations of Coronavirus Disease 2019 in the Emergency Department: A Retrospective Analysis

From Critical Care Explorations.  In this study, lung ultrasound diagnosed severe presentations of coronavirus disease 2019 with similar sensitivity to chest radiograph, CT, and reverse transcriptase-polymerase chain reaction (on first testing) and improved specificity compar...

   Estimated Time: 12:23 Coronavirus, COVID-19, Diagnosis and Testing

Letter to the Editor: Weaning by Surgical Tracheostomy and Portable Ventilators Released ICU Ventilators During Coronavirus Disease 2019 Surge in London

From Critical Care Explorations . In this Letter to the Editor from London, the authors share experiences with an integrated model of surgical tracheostomy weaning of respiratory critical care patients by a specialist mobile weaning team, using tracheostomy-licensed ventilato...

   Estimated Time: 7:57 Coronavirus, COVID-19, Ventilatory Support

Clinical Outcomes in Critically Ill Coronavirus Disease 2019 Patients: A Unique New York City Public Hospital Experience

From Critical Care Explorations . The authors explore demographics, comorbidities, transfers, and mortality in critically ill patients with confirmed severe acute respiratory syndrome coronavirus 2 in a New York City hospital.  

   Estimated Time: 25:38

Mortality Rates in a Diverse Cohort of Mechanically Ventilated Patients With Novel Coronavirus in the Urban Midwest

From Critical Care Explorations . In this study, the authors found mortality rates in mechanically ventilated patients with coronavirus disease 2019 to be lower than some previously reported with longer lengths of stay.  

   Estimated Time: 16:17 Coronavirus, COVID-19, Ventilatory Support