CDC Resources: Epidemiology-Outcomes
SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Centers for Disease Control and Prevention (CDC). These resources are categorized as Epidemiology-Outcomes
Plasma Soluble CD14 Subtype Levels Are Associated With Clinical Outcomes in Critically Ill Subjects With Coronavirus Disease 2019
Critical Care Explorations In this study, the authors concluded that soluble CD14 subtype levels may have prognostic utility in coronavirus disease 2019.
Identification of Aggravation-Predicting Gene Polymorphisms in Coronavirus Disease 2019 Patients Using a Candidate Gene Approach Associated With Multiple Phase Pathogenesis: A Study in a Japanese City of 1 Million People
From Critical Care Explorations In this observational study, the authors successfully identified significant genetic factors in OAS1 and IL1B genes using a candidate gene approach study as valuable information for further mechanistic investigation and predictive model building.
AHA Resource: How a Bold, New Strategy Took on Health Care Inequities During the Pandemic (Blog)
AHA published a new blog post from an LLN member hospital titled, The Pandemic. “How a Bold, New Strategy Took on Health Care Inequities During the Pandemic,” authored by Luminis Health Chief Diversity Officer Tamiko Stanley.
Trends in 28-Day Mortality of Critical Care Patients With Coronavirus Disease 2019 in United Kingdom: A National Cohort Study, March 2020 to January 2021
From Critical Care Medicine. The authors sought to determine whether the previously described trend of improving mortality in people with coronavirus disease 2019 in critical care during the first wave was maintained, plateaued, or reversed during the second wave in United Kingdom, when B117 became the dominant strain.
Surge and Mortality in ICUs in New York City’s Public Healthcare System
From Critical Care Medicine. The authors evaluate the impact of ICU surge on mortality and to explore clinical and sociodemographic predictors of mortality.
CDC Resources: Pediatrics
SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Centers for Disease Control and Prevention (CDC). These resources are categorized as Pediatrics
CDC Resources: Research
SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Centers for Disease Control and Prevention (CDC). These resources are categorized as Research
Coronavirus Disease 2019 Calls for Predictive Analytics Monitoring—A New Kind of Illness Scoring System
From Critical Care Explorations
The authors believe that current illness severity scoring systems, which usually update only when clinicians measure vital signs or laboratory values, are poorly suited for early detection of this kind of rapid clinical deterioration, and therefore propose that continuous predictive analytics monitoring, a new approach to bedside management, is more useful.
Harmonizing Heterogeneous Endpoints in Coronavirus Disease 2019 Trials Without Loss of Information
From Critical Care Medicine
The authors aim to provide hands-on statistical guidelines for harmonizing heterogeneous endpoints in coronavirus disease 2019 clinical trials.
Editorial: Survival From Severe Coronavirus Disease 2019: Is It Changing?
From Critical Care Medicine
In this editorial, the authors discuss the factors behind why patients had a higher likelihood of surviving coronavirus disease 2019 in June 2020 compared to March 2020.
Prognostic Factors for 30-Day Mortality in Critically Ill Patients With Coronavirus Disease 2019: An Observational Cohort Study
From Critical Care Medicine
The authors identified patient characteristics that predict an increased likelihood of death within 30 days of the start of critical care for patients with coronavirus disease 2019, which included age, ethnicity, deprivation, body mass index, and prior dependency, among other characteristics.
Tokyo and New York: A Study in the Contrasting Effects of Socioeconomic Status on Coronavirus Disease 2019 Outcomes
From Critical Care Explorations. The authors examined the association between socioeconomic status and the rate of coronavirus disease 2019 infections using public data from Tokyo.
Guiding Principles for the Conduct of Observational Critical Care Research for Coronavirus Disease 2019 Pandemics and Beyond: The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study Registry
From Critical Care Medicine. In this article, the authors describe how the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study coronavirus disease 2019 registry sought to develop and implement prespecified best practices combined with grassroots efforts from clinical sites worldwide in order to develop clinically useful knowledge in response to a pandemic.
Nationwide Incidence and Outcomes of Patients With Coronavirus Disease 2019 Requiring Intensive Care in Iceland
From Critical Care Medicine. In this study from Iceland, which had early adoption of widespread testing, the authors report a lower overall ratio of ICU admissions for coronavirus disease 2019 among severe acute respiratory syndrome coronavirus 2 positive patients and a lower hospital mortality for patients treated in the ICU for coronavirus disease 2019 compared with initial reports from Italy and China.
Letter to the Editor: Coronavirus Disease 2019: Understanding Immunopathogenesis Is the “Holy Grail” to Explain Why Children Have Less Severe Acute Disease
From Pediatric Critical Care Medicine. In this letter to the editor, the authors state that the understanding of the immunopathogenesis of SARS-CoV-2 infection is important not only to understand the epidemiologic and age-related differences in COVID-19, but it is critical for the identification of appropriate treatment, as well as for the development of a highly immunogenic vaccine with low risk of antibody dependent enhancement.
Gender Difference Is Associated With Severity of Coronavirus Disease 2019 Infection: An Insight From a Meta-Analysis
From Critical Care Explorations. This review article investigates how gender difference can affect the disease severity of COVID-19 infection.
Prediction of Pediatric Critical Care Resource Utilization for Disaster Triage
From Pediatric Critical Care Medicine. The authors sought to determine whether currently available pediatric illness severity scores can predict duration of critical care resource use.
COVID-19 Mortality Factors
This presentation discusses the mortality factors regarding COVID-19. This is SCCM curated COVID-19 microlearning content.
Pediatric concerns: Symptoms, diagnosis and mortality
This presentation is an overview of symptoms, diagnosis and mortality concerns seen when treating pediatric patients with COVID-19. This is SCCM curated COVID-19 microlearning content.
Age Distribution and Critical Illness Severity of COVID-19
This presentation is an overview of age distribution as it relates to severity in COVID-19 patients.