Evaluation of Hypertriglyceridemia in Critically Ill Patients With Coronavirus Disease 2019 Receiving Propofol

From Critical Care Explorations . In this study, the authors report the prevalence of, and evaluate risk factors for, the development of hypertriglyceridemia (defined as a serum triglyceride level of > 400 mg/dL) in patients with coronavirus disease 2019 who received propofol.

Correlation of Respiratory Physiologic Parameters in Mechanically Ventilated Coronavirus Disease 2019 Patients

From Critical Care Explorations . In this article, the authors report simultaneously measured respiratory parameters (static lung compliance, alveolar dead space ventilation, and shunt fraction) in 14 patients with advanced coronavirus disease 2019-related acute respiratory d...

The Effects of ICU Crisis Reorganization on Outcomes in Patients Not Infected With Coronavirus Disease 2019 During the Initial Surge of the Coronavirus Disease 2019 Pandemic

From Critical Care Explorations . In this study, the authors determined if ICU reorganization due to the coronavirus disease 2019 pandemic affected outcomes in critically ill patients who were not infected with coronavirus disease 2019.

Tocilizumab in Coronavirus Disease 2019-Related Critical Illness: A Propensity Matched Analysis

From Critical Care Explorations .  In this study, the authors evaluate ICU mortality at 28 days in patients with severe hypoxemic respiratory failure due to coronavirus disease 2019 infection who received tocilizumab. 

Severe Acute Respiratory Syndrome Coronavirus-2-Associated Acute Kidney Injury: A Narrative Review Focused Upon Pathophysiology

From Critical Care Medicine . In this article, the authors conclude that a personalized approach to each patient with acute kidney injury based on the timing and severity of disease is necessary in order to provide appropriate treatment.

Prevalence of Thrombotic Complications in ICU-Treated Patients With Coronavirus Disease 2019 Detected With Systematic CT Scanning

From Critical Care Medicine . In this study, the authors looked for the true prevalence of thrombotic complications in critically ill patients with severe coronavirus disease 2019 on the ICU, with or without extracorporeal membrane oxygenation.

Capillary Leukocytes, Microaggregates, and the Response to Hypoxemia in the Microcirculation of Coronavirus Disease 2019 Patients

From Critical Care Medicine . In this study, the authors hypothesized that coronavirus disease 2019 patients exhibit sublingual microcirculatory alterations caused by inflammation, coagulopathy, and hypoxemia.

Safety and Outcomes of Prolonged Usual Care Prone Position Mechanical Ventilation to Treat Acute Coronavirus Disease 2019 Hypoxemic Respiratory Failure

From Critical Care Medicine . In this study, the authors found that prolonged prone position ventilation was feasible and relatively safe with implications for wider adoption in treating critically ill coronavirus disease 2019 patients and acute respiratory distress syndrome ...

Core Outcome Measures for Trials in People With Coronavirus Disease 2019: Respiratory Failure, Multiorgan Failure, Shortness of Breath, and Recovery

From Critical Care Medicine . The authors sought to establish the core outcome measures for respiratory failure, multiple organ failure, shortness of breath, recovery, and mortality for trials in coronavirus disease 2019.

Readiness for and Response to Coronavirus Disease 2019 Among Pediatric Healthcare Providers: The Role of Simulation for Pandemics and Other Disasters

From Pediatric Critical Care Medicine Early preparation for the training and education of healthcare providers, as well as the continuation or modification of routine medical education programs, is of great importance in times of the coronavirus disease 2019 pandemic or o...

Portable Magnetic Resonance Imaging for ICU Patients

From Critical Care Explorations   In this case series of patients, the authors found use of portable MRI to be safe, feasible, and led to changes in clinical management based on imaging results.

Integral Use of Thromboelastography With Platelet Mapping to Guide Appropriate Treatment, Avoid Complications, and Improve Survival of Patients With Coronavirus Disease 2019–Related Coagulopathy

From Critical Care Explorations In this study, the authors round that thromboelastography with platelet mapping better characterizes the spectrum of coronavirus disease 2019 coagulation-related abnormalities and may guide more tailored, patient-specific therapies in thost...

Racial Differences in a Detroit, MI, ICU Population of Coronavirus Disease 2019 Patients

From Critical Care Medicine   Contrary to previously held beliefs surrounding the coronavirus 19 pandemic, this study found that, in critically ill patients infected with coronavirus disease 2019, people of color had a lower 28-day mortality than Whites with no difference ...

Coronavirus Disease 2019 Calls for Predictive Analytics Monitoring—A New Kind of Illness Scoring System

From Critical Care Explorations The authors believe that current illness severity scoring systems, which usually update only when clinicians measure vital signs or laboratory values, are poorly suited for early detection of this kind of rapid clinical deterioration, and t...

Thromboembolism, Hypercoagulopathy, and Antiphospholipid Antibodies in Critically Ill Coronavirus Disease 2019 Patients: A Before and After Study of Enhanced Anticoagulation

From Critical Care Explorations In this study, the authors sought to determine the prevalence of thrombotic events, functional coagulation tests, inflammatory biomarkers, and antiphospholipid antibodies before and after enhanced anticoagulation in critically ill coronaviru...

Effects of Inhaled Epoprostenol and Prone Positioning in Intubated Coronavirus Disease 2019 Patients With Refractory Hypoxemia

From Critical Care Explorations In this study, the authors found that, in critically ill, mechanically ventilated patients with coronavirus disease 2019 who had refractory hypoxemia, oxygenation improved to a greater extent with combined use of inhaled epoprostenol and pr...

Propofol-Associated Hypertriglyceridemia in Coronavirus Disease 2019 Versus Noncoronavirus Disease 2019 Acute Respiratory Distress Syndrome

From Critical Care Explorations In this study, the authors found that patients with coronavirus disease 2019 acute respiratory distress syndrome experienced a higher rate of propofol-associated hypertriglyceridemia than noncoronavirus disease 2019 acute respiratory distre...

An Algorithm for Classifying Patients Most Likely to Develop Severe Coronavirus Disease 2019 Illness

From Critical Care Explorations The authors developed an algorithm to assess whether someone is at high risk of admission to the ICU or dying from coronavirus disease 2019, should he or she test positive for coronavirus disease 2019.

Clinical Outcomes With the Use of Prophylactic Versus Therapeutic Anticoagulation in Coronavirus Disease 2019

From Critical Care Explorations In this study, the authors found an increase in inhospital mortality was observed among patients on preemptive therapeutic anticoagulation.

Letter to the Editor: Breaking Silos: The Team-Based Approach to Coronavirus Disease 2019 Pandemic Staffing

From Critical Care Explorations The authors describe experiences and lessons learned at NewYork-Presbyterian (NYP), one of the largest healthcare delivery systems in the United States, in creating an intercampus leadership teams to combat COVID-19.