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Category: Pharmacology

Propofol-Associated Hypertriglyceridemia in Coronavirus Disease 2019 Versus Noncoronavirus Disease 2019 Acute Respiratory Distress Syndrome

From Critical Care Explorations In this study, the authors found that patients with coronavirus disease 2019 acute respiratory distress syndrome experienced a higher rate of propofol-associated hypertriglyceridemia than noncoronavirus disease 2019 acute respiratory distre...

   Estimated Time: 23:03 min ARDS, Coronavirus, COVID-19, Therapies

Clinical Outcomes With the Use of Prophylactic Versus Therapeutic Anticoagulation in Coronavirus Disease 2019

From Critical Care Explorations In this study, the authors found an increase in inhospital mortality was observed among patients on preemptive therapeutic anticoagulation.

   Estimated Time: 21:54 min Anticoagulation, Coronavirus, COVID-19

A Propensity-Matched Cohort Study of Tocilizumab in Patients With Coronavirus Disease 2019

From Critical Care Explorations The authors assessed the impact of tocilizumab therapy and found that it was associated with significantly improved survival in coronavirus disease 2019 patients.

   Estimated Time: 23:31 Coronavirus, COVID-19, Therapies

Editorial: Coronavirus Disease 2019 Acute Respiratory Failure: Almitrine Drug Resuscitation or Resuscitating Patients by Almitrine?

From Critical Care Medicine In this editorial, the author discusses the seeming benefits of using almitrine for severe hypoxia in patients with coronavirus disease 19 induced acute respiratory distress syndrome.

   Estimated Time: 07:02 ARDS, Cardiovascular, Coronavirus, COVID-19

Delirium Incidence, Duration, and Severity in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations The authors found that mechanical ventilation was significantly associated with odds of delirium even after adjustment for sedatives.

   Estimated Time: 27:15 Coronavirus, COVID-19, Therapies, Ventilatory Support

Clinical Pharmacists: An Invaluable Part of the Coronavirus Disease 2019 Frontline Response

From Critical Care Explorations The authors describe how clinical pharmacists fulfilled an essential service during the coronavirus pandemic by working to ensure the best possible outcomes for the patients they served on the frontline.

   Estimated Time: 13:50 Coronavirus, COVID-19

Resolution of Coronavirus Disease 2019 Infection and Pulmonary Pathology With Nebulized DAS181: A Pilot Study

From Critical Care Explorations The authors investigated the safety and effects of nebulized DAS181 on hypoxic coronavirus disease 2019 patients.

   Estimated Time: 15:50 Coronavirus, COVID-19, Therapies

Volatile Isoflurane in Critically Ill Coronavirus Disease 2019 Patients—A Case Series and Systematic Review

From Critical Care Explorations The authors evalute the use of isoflurane in patients with coronavirus disease 2019–induced acute respiratory distress syndrome.

   Estimated Time: 22:23 min ARDS, Coronavirus, COVID-19, Therapies, Ventilatory Support

Almitrine Infusion in Severe Acute Respiratory Syndrome Coronavirus 2-Induced Acute Respiratory Distress Syndrome: A Single-Center Observational Study

From Critical Care Medicine The authors assessed the effect of almitrine, a selective pulmonary vasoconstrictor, on arterial oxygenation in severe acute respiratory syndrome coronavirus 2-induced acute respiratory distress syndrome.

   Estimated Time: 20:07 min ARDS, Coronavirus, COVID-19, Therapies

If a patient reports shortness of breath but has an oxygen saturation of 95%, is this patient a candidate for dexamethasone?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.

   Estimated Time: 01:50 min Coronavirus, Corticosteriods, COVID-19, Supportive Care

Have steroids been used after discharge?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.

   Estimated Time: 00:59 min Coronavirus, Corticosteriods, COVID-19

After a patient has tested positive for COVID-19, when is the most appropriate time to administer remdesivir to maximize its effectiveness?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.

   Estimated Time: 01:01 min Coronavirus, Corticosteriods, COVID-19

What is your experience with COVID-19 patients and ECMO?

Despite remdesivir, dexamethasone, and twice-daily anticoagulation, a patient’s condition continues to deteriorate. The patient is intubated, and every possible ventilation mode has been tried. The P/F ratio is decreasing, and pressure ventilation is not working. What is your ...

Which medications are used for a hemodynamically unstable intubated patient who is progressing toward or has developed acute respiratory distress syndrome? Are remdesivir or steroids used? What about anticoagulation, given the high risk of thrombosis?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.

For a stable patient on the ward who needs 2 to 4 liters of oxygen, is hemodynamically stable, and does not seem to be deteriorating, would you start a medication such as remdesivir or steroids or would you wait until the patient’s condition starts to det

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.

   Estimated Time: 02:20 min Antivirals, Coronavirus, COVID-19, Hemodynamic Support

Do you recommend calling pharmacy or infectious diseases for patients admitted to the ward with a positive COVID-19 test and some COVID-19 symptoms?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.

   Estimated Time: 02:10 min Coronavirus, COVID-19, Diagnosis and Testing

Are pharmacists well versed in which COVID-19 drugs to use?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.

   Estimated Time: 01:24 min Coronavirus, COVID-19

Would you use remdesivir or steroids as early as admittance to the emergency department? Do you advocate their use?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.

   Estimated Time: 00:39 min Antivirals, Coronavirus, Corticosteriods, COVID-19, Therapies

What is double anticoagulation prophylaxis?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.

   Estimated Time: 01:12 min Anticoagulation, Coronavirus, COVID-19

Are you using typical DVT prophylaxis or something more, such as therapeutic anticoagulation?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.

   Estimated Time: 02:08 min Anticoagulation, Coronavirus, COVID-19