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Category: Pharmacology

Editorial: Do Our Sedation Practices Contribute to Increased Mortality in Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome?

From Critical Care Medicine . In this Editorial, the authors discuss the article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Acute Respiratory Distress Syndr...

   Estimated Time: 10:13 min Coronavirus, COVID-19, Sedation

Tocilizumab for the Treatment of Severe COVID-19 Pneumonia in Critically Ill Patients: Trendy or Tried-and-True?

This resource details an the usage of tocilizumab as a treatment for severe COVID-19. This is SCCM curated COVID-19 microlearning content.

   Estimated Time: 05:20 min Coronavirus, COVID-19, Therapies

Now that patients are being vaccinated, when ruling out COVID-19 in patients who might have pneumonia or pulmonary embolism, how should their vaccination status be taken into account?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021

   Estimated Time: 01:29 min Coinfections, Comorbidities, Coronavirus, COVID-19

When should furosemide be used in COVID-19 patients? Some COVID-19 patients are presenting with diarrhea rather than respiratory symptoms. Is there any evidence-based treatment for this?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021

   Estimated Time: 01:46 min Comorbidities, Coronavirus, COVID-19

Can you discuss the use of anticoagulation for blood clot prevention in COVID-19 patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021

   Estimated Time: 06:38 min Anticoagulation, Coronavirus, COVID-19

Can you discuss sedation strategies for COVID-19 patients who are on mechanical ventilation or ECMO?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021

   Estimated Time: 03:12 min Coronavirus, COVID-19, ECMO, Ventilatory Support

For patients with COVID-19 being treated with intermediate- or full-dose enoxaparin, have anti-Xa levels been checked? If so, have higher-than-expected anti-Xa levels been found?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021

   Estimated Time: 2mins 22secs Coronavirus, COVID-19, Diagnosis and Testing

Should anticoagulation or antiplatelet therapy be used for patients with COVID-19? Should these patients be empirically anticoagulated? How is your institution handling this?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021

   Estimated Time: 3mins 59 secs Anticoagulation, Coronavirus, COVID-19

Does ketamine help resolve agitation or delirium? Are hallucinations a possible side effect of ketamine?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021

   Estimated Time: 2mins 6 secs Coronavirus, COVID-19, Delirium

For patients with severe acute respiratory distress syndrome from COVID-19, how do you prevent delirium when you cannot provide a sedation vacation or spontaneous breathing trial?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021

   Estimated Time: 3mins 2 secs ARDS, Coronavirus, COVID-19, Sedation

When delirium prevention measures are ineffective for ICU patients with delirium, which therapies do you recommend trying next?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021

   Estimated Time: 5 mins 30 secs Coronavirus, COVID-19, Delirium

Which environmental and medical therapies do you believe are most effective in preventing delirium in the ICU?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021

   Estimated Time: 3mins 31 secs ARDS, Coronavirus, COVID-19, Ventilatory Support

In Vitro–Administered Dexamethasone Suppresses T Cell Function With Reversal by Interleukin-7 in Coronavirus Disease 2019

From Critical Care Explorations . The authors evaluated the in vitro effects of dexamethasone phosphate on T cell function in peripheral blood mononuclear cells derived from patients with acute, severe, and moderate coronavirus disease 2019.

   Estimated Time: 09:48 min Coronavirus, Corticosteriods, COVID-19

Online Letter to the Editor: Is “Mega-Dose” IV Vitamin C Required for Septic and Critical Coronavirus Disease 2019 Patients?

From Critical Care Medicine . This online letter to the editor was written in response to “Reversal of the Pathophysiological Responses to Gram-Negative Sepsis by Megadose Vitamin C” by Lankadeva et al

   Estimated Time: 01:07 Coronavirus, COVID-19, Therapies

Online Letter to the Editor: Plasmapheresis Efficiency in Coronavirus Disease 2019: More Related to What You Add and Not What You Take Away?

From Critical Care Medicine . This is an online Letter to the Editor in response to the article by Fernandez et al. “Plasma Exchange: An Effective Rescue Therapy in Critically Ill Patients With Coronavirus Disease 2019 Infection.”

Standard Sedation and Sedation With Isoflurane in Mechanically Ventilated Patients With Coronavirus Disease 2019

From Critical Care Explorations . The authors describe sedative and analgesic drug utilization in a cohort of critically ill patients with coronavirus disease 2019 and compare standard sedation with an alternative approach using inhaled isoflurane.

   Estimated Time: 13:28 Coronavirus, COVID-19, Sedation, Ventilatory Support

What is the role of ivermectin in the treatment of COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021

   Estimated Time: 1:37 Coronavirus, COVID-19, Therapies

Which populations should be anticoagulated? What is the procedure for anticoagulation and how long should it take?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021  

   Estimated Time: 3:06 Anticoagulation, Coronavirus, COVID-19

When are steroids indicated for COVID-19? What is the appropriate dosage and duration?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021

   Estimated Time: 4:03 Coronavirus, Corticosteriods, COVID-19

What is the current role of tocilizumab?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on February 24, 2021

   Estimated Time: 3:50 Coronavirus, COVID-19, Therapies