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Category: Pharmacology

Regarding multimodality therapies, specifically steroids, what would you administer to a patient with COVID-19 today? If the patient were on remdesivir, would you continue the remdesivir for the full duration of therapy?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 14, 2021

   Estimated Time: 00:30 min Antivirals, Coronavirus, COVID-19

What is the most recent evidence on anticoagulation dosing for patients with COVID-19, specifically prophylactic versus treatment and duration of therapy?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 14, 2021

   Estimated Time: 04:12 min Anticoagulation, Coronavirus, COVID-19

When should steroids or a multimodality therapy be started in patients with COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 14, 2021

   Estimated Time: 08:35 min Coronavirus, Corticosteriods, COVID-19

What is the recommended Richmond Agitation-Sedation score goal for patients who had “happy hypoxia” and who then decompensate and require intubation?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 14, 2021

   Estimated Time: 00:38 min Coronavirus, COVID-19, Sedation

What is your approach to treatment and management now that more people have been vaccinated?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 14, 2021

   Estimated Time: 02:02 min Coronavirus, COVID-19

When is the most appropriate time to administer antibiotics versus targeted therapy, (e.g., a gastrointestinal source) for a patient with cyclical fevers? What is your approach to antibiotics for a patient with COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 14, 2021

   Estimated Time: 04:08 min Coronavirus, COVID-19, Therapies

Methylprednisolone and 60 Days in Hospital Survival in Coronavirus Disease 2019 Pneumonia

From Critical Care Explorations . In this study, the authors found that low-dose methylprednisolone was associated with reduced mortality if given greater than 7 days from onset of symptoms, and no additional benefit greater than 14 days; high dose was associated with higher ...

   Estimated Time: 27:10 min Coronavirus, COVID-19, Therapies

Treatments of Moderate and Severe COVID-19 Pneumonia

Antiviral and Immunomodulatory Therapies for COVID-19. This is SCCM curated COVID-19 microlearning content. Curriculum Topic:  Infectious Complications & Management of COVID-19 Infection / Nosocomial

   Estimated Time: 56:31 min Antivirals, Coronavirus, COVID-19, STOP VIRUS

Sedation Practices

Focus on ABC elements of the ICU Liberation Bundle, specifically, 1) depth of sedation, 2) choosing the right agent, 3) daily interruption of sedation. This is SCCM curated COVID-19 microlearning content. Curriculum Topic:  ICU Liberation Bundle Implementation & Challenges

   Estimated Time: 41:02 min Coronavirus, COVID-19, Sedation, STOP VIRUS

Review of Approved Monoclonal Antibody Treatments for COVID-19

This resource details monoclonal antibody treatments that can be used to treat COVID-19. This is SCCM curated COVID-19 microlearning content.

   Estimated Time: 10:07 min Coronavirus, COVID-19, Therapies

Pharmacotherapy in Coronavirus Disease 2019 and Risk of Secondary Infections: A Single-Center Case Series and Narrative Review

From Critical Care Explorations . The authors sought to evaluate the impact of pharmacologic approach to coronavirus disease 2019 within the ICU on secondary infections and clinical outcomes.

   Estimated Time: 30:18 min Coronavirus, COVID-19

Can you address some of the issues regarding the AstraZeneca and Johnson & Johnson vaccines being prothrombotic in pregnancy?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

   Estimated Time: 02:13 min Coronavirus, COVID-19, OB/GYN, Vaccines

Have any studies been done with immunoglobulin instead of prolactin?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

   Estimated Time: 01:43 min Coronavirus, COVID-19, Therapies

How would you address the recent literature about prolactin as an immunomodulator for COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

   Estimated Time: 0:58 min Coronavirus, COVID-19, Therapies

What doses of dexamethasone, antivirals, and immunomodulators do you recommend?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

   Estimated Time: 02:03 min Coronavirus, COVID-19, Therapies

Using Nonheparin Anticoagulant to Treat a Near-Fatal Case With Multiple Venous Thrombotic Lesions During ChAdOx1 nCoV-19 Vaccination-Related Vaccine-Induced Immune Thrombotic Thrombocytopenia

From Critical Care Medicine . The authors describe the successful recovery from multiple and life-threatening venous thrombosis after ChAdOx1 nCoV-19 vaccination.

   Estimated Time: 09:06 min Anticoagulation, Coronavirus, COVID-19, Vaccines

Online Letter to the Editor: Reasons for the Overuse of Sedatives and Deep Sedation for Mechanically Ventilated Coronavirus Disease 2019 Patients

From Critical Care Medicine . This Online Letter to the Editor was written in response to an article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019-Related Acute Respir...

   Estimated Time: 02:40 min Coronavirus, COVID-19, Sedation, Ventilatory Support

Online Letter to the Editor: The Janus Face of Coronavirus Disease 2019–Associated Coagulopathy

From Critical Care Medicine . This Online Letter to the Editor is in response to an article by Doyle et al. entitled “A comparison of thrombosis and hemorrhage rates in patients with severe respiratory failure due to coronavirus disease 2019 and influenza requiring extracorpo...

   Estimated Time: 03:39 min Anticoagulation, ARDS, Coronavirus, COVID-19, ECMO

Online Letter to Editor: Optimal Patient Selection for the Prophylactic Anticoagulation Therapy in Patients With Coronavirus Disease 2019

From Critical Care Medicine . This Online Letter to the Editor was written in response to an article by Santoro et al. entitled “Anticoagulation Therapy in Patients With Coronavirus Disease 2019: Results From a Multicenter International Prospective Registry (Health Outcome Pr...

   Estimated Time: 01:42 min Coronavirus, COVID-19, Therapies

Editorial: Do Our Sedation Practices Contribute to Increased Mortality in Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome?

From Critical Care Medicine . In this Editorial, the authors discuss the article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Acute Respiratory Distress Syndr...

   Estimated Time: 10:13 min Coronavirus, COVID-19, Sedation