Online Letter to the Editor: Analysis of Critical Care Severity of Illness Scoring Systems in Patients With Coronavirus Disease 2019: A Retrospective Analysis of Three U.K. ICUs

From Critical Care Medicine In this letter, the authors discuss APACHE II scores being used to predict mortality in coronavirus disease 2019 patients, however it may not be replicable.

Early Percutaneous Tracheostomy in Coronavirus Disease 2019: Association With Hospital Mortality and Factors Associated With Removal of Tracheostomy Tube at ICU Discharge. A Cohort Study on 121 Patients

From Critical Care Medicine This study shows how early percutaneous tracheostomy was safe and effective in coronavirus disease 2019 patients, giving a good chance of survival and of weaning from tracheostomy cannula at ICU discharge.

Editorial: Coronavirus Disease 2019 Acute Respiratory Failure: Almitrine Drug Resuscitation or Resuscitating Patients by Almitrine?

From Critical Care Medicine In this editorial, the author discusses the seeming benefits of using almitrine for severe hypoxia in patients with coronavirus disease 19 induced acute respiratory distress syndrome.

Editorial: Cardiopulmonary Resuscitation in Coronavirus Disease 2019: Rebalancing Risk, Reward, and Autonomy

From Critical Care Medicine In this editorial, the authors discuss the risks of healthcare professionals performing cardiopulmonary resuscitation on coronavirus disease 2019 patients.

Editorial: Survival From Severe Coronavirus Disease 2019: Is It Changing?

From Critical Care Medicine In this editorial, the authors discuss the factors behind why patients had a higher likelihood of surviving coronavirus disease 2019 in June 2020 compared to March 2020.

Prognostic Factors for 30-Day Mortality in Critically Ill Patients With Coronavirus Disease 2019: An Observational Cohort Study

From Critical Care Medicine The authors identified patient characteristics that predict an increased likelihood of death within 30 days of the start of critical care for patients with coronavirus disease 2019, which included age, ethnicity, deprivation, body mass index, an...

Unexpectedly High Frequency of Enterococcal Bloodstream Infections in Coronavirus Disease 2019 Patients Admitted to an Italian ICU: An Observational Study

From Critical Care Medicine The authors found that coronavirus disease 2019 seemed to increase the frequency of bloodstream infections (particularly Enterococcus-related bloodstream infection) after ICU admission.

Procalcitonin Exerts a Mediator Role in Septic Shock Through the Calcitonin Gene-Related Peptide Receptor

From Critical Care Medicine The authors found that procalcitonin exerts a moderate but harmful effect on disease progression in experimental septic shock, and suggests a potential therapeutic application for calcitonin gene-related peptide receptor inhibitors in sepsis.

De Novo Renal Failure and Clinical Outcomes of Patients With Critical Coronavirus Disease 2019

From Critical Care Medicine  The authors found that respiratory failure conveys significant mortality risk in patients with coronavirus disease 2019 and survival with concomitant renal failure is rare.

Validation of Inflammopathic, Adaptive, and Coagulopathic Sepsis Endotypes in Coronavirus Disease 2019

From Critical Care Medicine The authors tested and found that a previously defined bacterial sepsis endotype classifier recapitulates the same clinical and immunological endotypes in viral sepsis (coronavirus disease 2019).

Reversal of the Pathophysiological Responses to Gram-Negative Sepsis by Megadose Vitamin C

From Critical Care Medicine The authors invesitated the safety and efficacy of megadose sodium ascorbate in sepsis.

Rapid Transition of a PICU Space and Staff to Adult Coronavirus Disease 2019 ICU Care

From Critical Care Medicine The authors describe how a PICU and a PICU care team were incorporated into a hospital-wide ICU care model during the coronavirus disease 2019 pandemic.

Letter to the Editor: Predictors of Mortality and Effect of Drug Therapies in Mechanically Ventilated Patients With Coronavirus Disease 2019: A Multicenter Cohort St

From Critical Care Explorations The authors conducted a multicenter cohort study to determine the effect of drug therapies on survival in mechanically ventilated patients with coronavirus disease 2019.

Delirium Incidence, Duration, and Severity in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations The authors found that mechanical ventilation was significantly associated with odds of delirium even after adjustment for sedatives.

Brain Death Evaluation in Children With Suspected or Confirmed Coronavirus Disease 2019

From Pediatric Critical Care Medicine The authors discuss the challenges of conducting a death by neurologic criteria or brain death evaluation in the coronavirus disease 2019 era and provide guidance to mitigate viral transmission risk and maintain patient safety during ...

Feasibility and Safety of Prone Position Transport for Severe Hypoxemic Respiratory Failure Due to Coronavirus Disease 2019

From Critical Care Explorations The authors found that critical care transport of severe hypoxemic respiratory failure patients with coronavirus disease 2019 in the prone position is safe when performed by a dedicated team of critical care nurse and paramedics with an est...

Experience With Cardiology-Oriented Outcomes in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations The authors share data and recommendations from a multidisciplinary team to highlight our institution’s clinical experiences and guidelines for managing cardiovascular complications of coronavirus disease 2019.

A Novel Low-Cost Ventilator for Use in a Worldwide Pandemic: The Portsmouth Ventilator

From Critical Care Explorations In this study, the authors found that the Portsmouth Ventilator was able to perform well across all simulated pathologies and in vivo.

Clinical Pharmacists: An Invaluable Part of the Coronavirus Disease 2019 Frontline Response

From Critical Care Explorations The authors describe how clinical pharmacists fulfilled an essential service during the coronavirus pandemic by working to ensure the best possible outcomes for the patients they served on the frontline.

A Method to Improve Continuous Renal Replacement Therapy Circuit Survival Time in Critically Ill Coronavirus Disease 2019 Patients With Acute Kidney Injury

From Critical Care Explorations The authors discuss optimizing continuous renal replacement therapy circuit survival in coronavirus disease 2019 patients admitted to the ICU.