PCCM Audio Summary - September 2025

The September 2025 issue of Pediatric Critical Care Medicine (PCCM) features original research articles investigating sepsis-associated acute kidney injury subphenotypes, the impact of airway closure on respiratory mechanics in patients with acute bronchiolitis, risk analytics algorithms to predict extubation failure in children after cardiac surgery, and palliative care in children with heart disease supported with mechanical circulatory support. Clinical investigation articles focus on optimal thromboprophylaxis modalities in critically ill adolescents, issues affecting collaboration and mutuality with families of children in the pediatric intensive care unit who have severe neurologic impairment, clinician versus family perspectives on outcomes in critically ill ventilated patients, and changes in mechanical ventilation settings in neonates after cardiac surgery. The PCCM editorial commentary by Jacques R. Lacroix, MD, discusses precautions to be taken when using a restrictive versus liberal red blood cell transfusion strategy in children with severe acute brain injury.

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