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Category: Pharmacology

Sedation and Analgesia: Practical Drug Selection and Pharmacolog

This is a presentation from the 2017 Multiprofessional Critical Care Review Course: Adult (MCCRC) on sedation and analgesia.

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Drug Shortages: Peripheral Vasopressors: Friend or Foe?

This article was first published in the May/June/July 2019 issue of Critical Connections . The Drug Shortages column addresses recent events and issues related to drug shortages. Hemodynamic emergencies are common in the critical care arena. Once fluid resuscitation fails t...

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Drug Shortages: Analgesic Alternatives to Opioid Drug Shortages

This article was first published in the August 2018 issue of Critical Connections. The Drug Shortages Committee is a multiprofessional group charged with providing resources to members to help optimally manage drug shortages affecting critically ill and injured patients. Commi...

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Standard Medication Concentrations: An Opportunity to Reduce Medication Errors

This article was first published in the February 2019 issue of Critical Connections. The Drug Shortages column addresses recent events and issues related to drug shortages.

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Drug Shortages: SCCM Participates in National Summit on Drug Shortages

This article was first published in the February 2018 issue of Critical Connections. The Drug Shortages column addresses recent events and issues related to drug shortages.

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Drug Shortages: A “Basic” Reality: Managing Sodium Bicarbonate and Acetate Shortages

This article was first published in the December 2018 issue of Critical Connections. The Drug Shortages column addresses recent events and issues related to drug shortages.

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Drug Shortages: Communicating With Patients and Families About the Need for Alternative Drug Therapies

This article was first published in the December 2018 issue of Critical Connections. The Drug Shortages column addresses recent events and issues related to drug shortages.

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Drug Shortages: Safety of Antiepileptics During Drug Shortages

This article was first published in the June 2018 issue of Critical Connections. The Drug Shortages column addresses recent events and issues related to drug shortages. 

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Drug Withdrawal Syndromes: Managing Our Drugs or Theirs

This is a complimentary chapter from the textbook: Current Concepts in Adult Critical Care titled, "Drug Withdrawal Syndromes: Managing Our Drugs or Theirs"

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Guidelines for Sustained Neuromuscular Blockade in the Adult Critically Ill Patient

A Statement for Healthcare Professionals from the Neurocritical Care Society and Society of Critical Care Medicine​. 

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Safe Medication Use in the ICU

Clinical Practice Guideline: Safe Medication Use in the ICU  provides ICU clinicians with evidence-based guidance on safe medication use practices for the critically ill. Crit Care Med 2017; 45(9):e877-e915

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Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU

The Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU, known as the PADIS Guidelines, are an update to the 2013 Pain, Agitation, Delirium Guidelines.

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Drug Shortage Alert: General Considerations (December 2012)

This drug shortage alert is designed to assist the multiprofessional team with implementing a consistent and safe approach to managing drug shortages by highlighting key strategic planning considerations.

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Drug Shortage Alert: Fosphenytoin (October 2017)

This summary provides information in the event of a fosphenytoin shortage and its impact on adult and pediatric patients, providing management strategies, pharmacotherapeutic considerations, and safety considerations. The recommendations provided are based on a combination of ...

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Drug Shortage Alert: Alternative Medications for Procedural Sedation (October 2017)

Medications frequently used for procedural sedation are currently being affected by shortages due to manufacturer discontinuation and/or increased demand. These alternative medication recommendations can be considered when a drug shortage arises within a particular class of me...

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SCCM Pod-VCCR3 Activated Charcoal in the Overdose Patient

Sean P. Kane, PharmD, BCPS, speaks with Frank Paloucek, PharmD, DABAT about the use of activated charcoal in the overdose patient.

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SCCM Pod-VCCR4 Common Sedatives and Paralytics for Rapid Sequence Intubation

Sean P. Kane, PharmD, BCPS, speaks with Joseph Muench, PharmD, BCPS about airway pharmacology. In the episode, the most common sedatives and paralytics for rapid sequence intubation are discussed, including concepts regarding dosing, adverse effects, onset and duration of effe...

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SCCM Pod-VCCR5 Rumack-Matthew Nomogram and Acetaminophen Toxicity

Sean P. Kane, PharmD, BCPS, speaks with Nadia Awad, PharmD, BCPS about Rumack-Matthew nomogram and acetaminophen toxicity.

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SCCM Pod-VCCR8 Ketamine for Refractory Status Epilepticus

Sean P. Kane, PharmD, BCPS, speaks with Karen Berger, PharmD, BCPS, BCCCP about refractory status epilepticus.

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Altered Mental Status During Critical Illness: Delirium and Coma

This is a complimentary chapter from Comprehensive Critical Care: Adult, Second Edition (2017), titled "Altered Mental Status During Critical Illness: Delirium and Coma." Comprehensive Critical Care: Adult is the most complete critical care textbook for any learner in adult p...

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